ID | 31331 |
JaLCDOI | |
フルテキストURL | |
著者 |
Kawakami, Yasuhiro
Okayama University
Suemaru, Katsuya
Okayama University
Araki, Hiroaki
Okayama Univeristy
Gomita, Yutaka
Okayama University
Tanizaki, Yoshiro
Okayama University
|
抄録 | The cross-sensitization to stereotyped behavior between mazindol (MZD) and methamphetamine (MAP) was investigated in rats. MZD (5 and 10 mg/kg/day, p.o.), MAP (5 and 10 mg/kg/day, p.o.) and saline (1 ml/kg, p.o.) were administered once daily for a week. Challenge with MZD (10 mg/kg, p.o.) on the 8th day caused markedly stereotyped behavior in MAP-pretreated group compared with the saline-pretreated control group. MAP (10 mg/kg, p.o.)-induced stereotyped behavior on the 8th day was also greater in MZD-pretreated group rather than the saline-pretreated control group. These results suggest that repeated MZD and MAP administration cross-sensitizes to their stereotype-producing effects. |
キーワード | mazindoi
methamphetamine
cross-sensitization
stereotyped behavior
|
Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1998-06
|
巻 | 52巻
|
号 | 3号
|
出版者 | Okayama University Medical School
|
開始ページ | 169
|
終了ページ | 171
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
|
PubMed ID | |
Web of Science KeyUT |