ID | 53064 |
フルテキストURL | |
著者 |
Kondo, Yoshitaka
Okayama Univ, Dept Surg Gastroenterol, Grad Sch Med Dent & Pharmaceut Sci
ORCID
Kaken ID
researchmap
Nagasaka, Takeshi
Okayama Univ, Dept Surg Gastroenterol, Grad Sch Med Dent & Pharmaceut Sci
ORCID
Kaken ID
publons
researchmap
Kobayashi, Satoru
3D Matrix Ltd
Kobayashi, Naoya
Okayama Univ, Dept Surg Gastroenterol, Grad Sch Med Dent & Pharmaceut Sci
Fujiwara, Toshiyoshi
Okayama Univ, Dept Surg Gastroenterol, Grad Sch Med Dent & Pharmaceut Sci
ORCID
Kaken ID
publons
researchmap
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抄録 | Background/Aims: PuraMatrix is a synthetic material consisting of 16-amino acid peptides that self-assemble into nanofibers, previously used as a scaffold for functional cell cultures. We conducted a clinical study to determine the safety and sealing properties of PuraMatrix in post-operative lymphorrhea following pelvic surgery in humans. Methodology: A total of 20 patients who underwent rectal cancer resection were analyzed. The study group (n = 10) consisted of patients who received PuraMatrix, matched with a control group (n = 10) of patients operated on conventionally. Results: During the 2 to 3 month follow-up period, there were no abnormal findings or adverse events in any the patients who received PuraMatrix. We found that the patients who received PuraMatrix had significantly reduced post-operative drainage volumes compared with the patients in the control group. Conclusions: PuraMatrix is a safe and effective bio-compatible sealing material for the management of post-operative peritoneal effusion following pelvic surgery.
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キーワード | Peritoneal effusion
Nanofiber polypeptide
Lymphorrhea
Pelvic surgery
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発行日 | 2014-03
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出版物タイトル |
Hepato-Gastroenterology
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巻 | 61巻
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号 | 130号
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開始ページ | 349
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終了ページ | 353
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ISSN | 0172-6390
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資料タイプ |
学術雑誌論文
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関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/51449
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言語 |
英語
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論文のバージョン | author
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査読 |
有り
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Web of Science KeyUT |