| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Shien, Tadahiko| Nakamoto, Shogo| Fujiwara, Yuki| Kosaka, Maya| Narahara, Yuki| Fujii, Kento| Maeda, Reina| Kato, Shutaro| Mimata, Asuka| Yoshioka, Ryo| Kuwahara, Chihiro| Tsukioki, Takahiro| Takahashi, Yuko| Iwatani, Tsuguo| Tanioka, Maki| |
| キーワード | oligo-recurrence breast cancer local therapy |
| 発行日 | 2025-07-21 |
| 出版物タイトル | Cancers |
| 巻 | 17巻 |
| 号 | 14号 |
| 出版者 | MDPI AG |
| 開始ページ | 2406 |
| ISSN | 2072-6694 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2025 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 40723288 |
| DOI | 10.3390/cancers17142406 |
| Web of Science KeyUT | 001539738700001 |
| 関連URL | isVersionOf https://doi.org/10.3390/cancers17142406 |
| フルテキストURL | fulltext.pdf suppl.docx |
|---|---|
| 著者 | Shien, Tadahiko| Hara, Fumikata| Aogi, Kenjiro| Yanagida, Yasuhiro| Tsuneizumi, Michiko| Yamamoto, Naohito| Matsumoto, Hiroshi| Suto, Akihiko| Watanabe, Kenichi| Harao, Michiko| Kanbayashi, Chizuko| Itoh, Mitsuya| Kadoya, Takayuki| Anan, Keisei| Maeda, Shigeto| Sasaki, Keita| Ogawa, Gakuto| Saji, Shigehira| Fukuda, Haruhiko| Iwata, Hiroji| |
| 発行日 | 2025-07-04 |
| 出版物タイトル | British Journal of Cancer |
| 出版者 | Springer Science and Business Media LLC |
| ISSN | 0007-0920 |
| NCID | AA00574355 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2025 |
| 論文のバージョン | publisher |
| PubMed ID | 40615712 |
| DOI | 10.1038/s41416-025-03097-z |
| Web of Science KeyUT | 001523009900001 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41416-025-03097-z |
| フルテキストURL | fulltext.pdf suppl.docx |
|---|---|
| 著者 | Shien, Tadahiko| Nogi, Hiroko| Ogiya, Akiko| Ishitobi, Makoto| Yamauchi, Chikako| Shimo, Ayaka| Narui, Kazutaka| Nagura, Naomi| Seki, Hirohito| Terata, Kaori| Saiga, Miho| Uchida, Tatsuya| Sasada, Shinsuke| Sakurai, Teruhisa| Niikura, Naoki| Mori, Hiroki| |
| キーワード | Breast cancer Immediate reconstruction surgery Prognosis Complications |
| 備考 | The version of record of this article, first published in Breast Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12282-025-01723-5| |
| 発行日 | 2025-05-26 |
| 出版物タイトル | Breast Cancer |
| 巻 | 32巻 |
| 号 | 4号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 630 |
| 終了ページ | 637 |
| ISSN | 1340-6868 |
| NCID | AA1103354X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2025 |
| 論文のバージョン | publisher |
| PubMed ID | 40418512 |
| DOI | 10.1007/s12282-025-01723-5 |
| Web of Science KeyUT | 001494864200001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s12282-025-01723-5 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tsukioki, Takahiro| Takata, Nozomu| Dennis, Saya R.| Terata, Kaori| Sagara, Yasuaki| Sakai, Takehiko| Takayama, Shin| Kitagawa, Dai| Kikawa, Yuichiro| Takahashi, Yuko| Iwatani, Tsuguo| Hara, Fumikata| Fujisawa, Tomomi| Shien, Tadahiko| |
| キーワード | Breast cancer FACT-B FACT-B+4 QOL |
| 備考 | The version of record of this article, first published in Breast Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12282-025-01701-x| |
| 発行日 | 2025-05-08 |
| 出版物タイトル | Breast Cancer |
| 巻 | 32巻 |
| 号 | 4号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 773 |
| 終了ページ | 782 |
| ISSN | 1340-6868 |
| NCID | AA1103354X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2025 |
| 論文のバージョン | publisher |
| PubMed ID | 40338515 |
| DOI | 10.1007/s12282-025-01701-x |
| Web of Science KeyUT | 001483857300001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s12282-025-01701-x |
| フルテキストURL | fulltext20250507-01.pdf |
|---|---|
| 著者 | Matsuo, Toshihiko| Tanaka, Takehiro| Shien, Tadahiko| Muraoka, Atsushi| Doihara, Hiroyoshi| |
| キーワード | breast cancer chemotherapy choroidal metastasis estrogen receptor her2 immunostaining invasive ductal carcinoma ki-67 progesterone receptor radiation |
| 発行日 | 2025-05-04 |
| 出版物タイトル | Cureus |
| 巻 | 17巻 |
| 号 | 5号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | e83484 |
| ISSN | 2168-8184 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Copyright 2025 Matsuo et al. |
| 論文のバージョン | publisher |
| PubMed ID | 40470417 |
| DOI | 10.7759/cureus.83484 |
| 関連URL | isVersionOf https://doi.org/10.7759/cureus.83484 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Mamori, Tomoka| Tanioka, Maki| Takada, Kenji| Hamano, Hirofumi| Tsukioki, Takahiro| Takahashi, Yuko| Iwatani, Tsuguo| Shien, Tadahiko| Toyooka, Shinichi| |
| 備考 | The version of record of this article, first published in BioDrugs, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40259-024-00686-x| |
| 発行日 | 2024-10-16 |
| 出版物タイトル | BioDrugs |
| 巻 | 39巻 |
| 号 | 1号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 131 |
| 終了ページ | 142 |
| ISSN | 1173-8804 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 39412713 |
| DOI | 10.1007/s40259-024-00686-x |
| Web of Science KeyUT | 001333384600001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s40259-024-00686-x |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Shien, Tadahiko| Tsuda, Hitoshi| Sasaki, Keita| Mizusawa, Junki| Akiyama, Futoshi| Kurosumi, Masafumi| Sawaki, Masataka| Tamura, Nobuko| Tanaka, Kiyo| Kogawa, Takahiro| Takahashi, Mina| Hayashi, Naoki| Mukai, Hirofumi| Masuda, Norikazu| Hara, Fumikata| Iwata, Hiroji| |
| キーワード | Breast cancer Neoadjuvant chemoradiotherapy Pathological therapeutic effect Specimen sampling method |
| 備考 | The version of record of this article, first published in Breast Cancer Research and Treatment, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10549-024-07408-5| |
| 発行日 | 2024-06-27 |
| 出版物タイトル | Breast Cancer Research and Treatment |
| 巻 | 208巻 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 145- |
| 終了ページ | 154 |
| ISSN | 0167-6806 |
| NCID | AA10623184 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38935214 |
| DOI | 10.1007/s10549-024-07408-5 |
| Web of Science KeyUT | 001256954600001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s10549-024-07408-5 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nakamoto, Shogo| Shien, Tadahiko| Iwamoto, Takayuki| Kubo, Shinichiro| Yamamoto, Mari| Yamashita, Tetsumasa| Kuwahara, Chihiro| Ikeda, Masahiko| |
| 発行日 | 2024-04-30 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 9869 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38684839 |
| DOI | 10.1038/s41598-024-60101-x |
| Web of Science KeyUT | 001211286800006 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-024-60101-x |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Swe, Hnin‐Wint‐Wint| Fujisawa, Masayoshi| Ohara, Toshiaki| Komatsubara, Yu| Yoshimura, Teizo| Shien, Tadahiko| Matsukawa, Akihiro| |
| キーワード | angiogenesis blood vessels breast cancer CD31 antigen immunohistochemistry microvessel density survival analysis |
| 発行日 | 2024-05-31 |
| 出版物タイトル | Pathology International |
| 巻 | 74巻 |
| 号 | 7号 |
| 出版者 | Wiley |
| 開始ページ | 394 |
| 終了ページ | 407 |
| ISSN | 1320-5463 |
| NCID | AA10984364 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 38818885 |
| DOI | 10.1111/pin.13442 |
| Web of Science KeyUT | 001235649700001 |
| 関連URL | isVersionOf https://doi.org/10.1111/pin.13442 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Otani, Yusuke| Katayama, Haruyoshi| Zhu, Yidan| Huang, Rongsheng| Shigehira, Takafumi| Shien, Kazuhiko| Suzawa, Ken| Yamamoto, Hiromasa| Shien, Tadahiko| Toyooka, Shinichi| Fujimura, Atsushi| |
| キーワード | adrenaline cancer-associated Schwann cells doublecortin microenvironment YAP/TAZ |
| 発行日 | 2024-04-27 |
| 出版物タイトル | Cancer Science |
| 巻 | 115巻 |
| 号 | 7号 |
| 出版者 | Wiley |
| 開始ページ | 2333 |
| 終了ページ | 2345 |
| ISSN | 1347-9032 |
| NCID | AA11808050 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38676373 |
| DOI | 10.1111/cas.16164 |
| Web of Science KeyUT | 001208622800001 |
| 関連URL | isVersionOf https://doi.org/10.1111/cas.16164 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Sasada, Shinsuke| Kondo, Naoto| Hashimoto, Hiroya| Takahashi, Yuko| Terata, Kaori| Kida, Kumiko| Sagara, Yasuaki| Ueno, Takayuki| Anan, Keisei| Suto, Akihiko| Kanbayashi, Chizuko| Takahashi, Mina| Nakamura, Rikiya| Ishiba, Toshiyuki| Tsuneizumi, Michiko| Nishimura, Seiichiro| Naito, Yoichi| Hara, Fumikata| Shien, Tadahiko| Iwata, Hiroji| |
| キーワード | Breast cancer T1a/b Endocrine therapy Estrogen receptor Prognosis |
| 備考 | The version of record of this article, first published in Breast Cancer Research and Treatment, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10549-023-07097-6| |
| 発行日 | 2023-09-09 |
| 出版物タイトル | Breast Cancer Research and Treatment |
| 巻 | 202巻 |
| 号 | 3号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 473 |
| 終了ページ | 483 |
| ISSN | 0167-6806 |
| NCID | AA10623184 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 37688665 |
| DOI | 10.1007/s10549-023-07097-6 |
| Web of Science KeyUT | 001065105700004 |
| 関連URL | isVersionOf https://doi.org/10.1007/s10549-023-07097-6 |
| JaLCDOI | 10.18926/AMO/66676 |
|---|---|
| フルテキストURL | 78_1_089.pdf |
| 著者 | Toshima, Kei| Shien, Tadahiko| Nishimura, Midori Filiz| Suzuki, Yoko| Nakamoto, Shogo| Uno, Maya| Yoshioka, Ryo| Tsukioki, Takahiro| Takahashi, Yuko| Iwamoto, Takayuki| Iwatani, Tsuguo| Yanai, Hiroyuki| |
| 抄録 | We report our experience with the diagnosis and treatment of an ectopic breast cancer arising within an axillary lymph node. The patient was a 65-year-old woman diagnosed breast cancer and axillary lymph node metastasis. We performed a partial mastectomy and axillary lymph node dissection. Postoperative pathology revealed no malignant lesions in the breast; however, a nodule in one of axillary lymph nodes had mixed benign and malignant components, leading to a diagnosis of invasive ductal carcinoma derived from ectopic mammary tissue. This case represents a very rare form of breast cancer, and the malignancy was difficult to distinguish from metastasis. |
| キーワード | breast cancer ectopic breast cancer axillary lymph node |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 89 |
| 終了ページ | 93 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419320 |
| Web of Science KeyUT | 001204421300001 |
| JaLCDOI | 10.18926/AMO/66666 |
|---|---|
| フルテキストURL | 78_1_015.pdf |
| 著者 | Maeda, Reina| Shien, Tadahiko| Takahashi, Mina| Kawada, Kengo| Kajiwara, Yukiko| Kubo, Shinichiro| Takabatake, Daisuke| Ohtani, Shoichiro| Matsuoka, Kinya| Hikino, Hajime| Ogasawara, Yutaka| Taira, Naruto| Osumi, Shozo| Ikeda, Masahiko| Doihara, Hiroyoshi| |
| 抄録 | While local treatment of metastases is considered to be unrelated to prognosis, previous studies have suggested that local treatment of isolated lung metastases may have positive prognostic impact. We designed this prospective cohort study to investigate the clinical situation and its outcomes. We enrolled patients with fewer than 3 lung nodules suspected of being oligometastases after curative breast cancer surgery. Treatments, including local and systemic therapy, were selected by the physician and patient in consultation. The primary outcome was overall survival (OS); secondary outcomes were the efficacy and the safety of the surgery for lung oligometastases. Between May 2015 and May 2019, 14 patients were enrolled. Resection of lung nodules (metastasectomy) was performed in 11 (78.6%) of 14 patients, and one of these cases was diagnosed as primary lung cancer. Metastasectomies were all performed employing video-assisted thoracic surgery (VATS) without perioperative complications. Systemic therapies were administered to all patients except one. The respective 3-year and 5-year OS rates of patients with lung oligometastases were 91.6% and 81.5%, respectively. Progression occurred in 6 patients: 3 of the 10 with metastasectomy and all 3 without this surgical procedure. Lung metastasectomy was worthwhile as a diagnostic evaluation and may provide long-term benefit in some patients. |
| キーワード | oligometastasis breast cancer lung metastasectomy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 15 |
| 終了ページ | 20 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419310 |
| Web of Science KeyUT | 001203658200008 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tsukioki, Takahiro| Khan, Seema A.| Shien, Tadahiko| |
| キーワード | Breast cancer Prevention Risk reduction mastectomy Chemoprevention Methylation |
| 備考 | The version of record of this article, first published in Genes and Environment, is available online at Publisher’s website: http://dx.doi.org/10.1186/s41021-023-00287-0| |
| 発行日 | 2023-12-12 |
| 出版物タイトル | Genes and Environment |
| 巻 | 45巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 35 |
| ISSN | 1880-7046 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 38082340 |
| DOI | 10.1186/s41021-023-00287-0 |
| Web of Science KeyUT | 001121724100001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s41021-023-00287-0 |
| JaLCDOI | 10.18926/AMO/64356 |
|---|---|
| フルテキストURL | 77_1_11.pdf |
| 著者 | Watanabe, Satoko| Saiga, Miho| Motoki, Takayuki| Shien, Tadahiko| Taira, Naruto| Doihara, Hiroyoshi| Kimata, Yoshihiro| |
| 抄録 | The importance of a well-fitted, comfortable brassiere to overall quality of life after breast reconstruction has not been evaluated. Our aim was to determine the impact of a semi-customized brassiere on patients’ health-related quality of life after breast reconstruction. The subjects were prospective patients with mastectomy who were to undergo immediate or delayed breast reconstruction at our hospital. After surgery, a professional bra fitter sized each patient for a semi-customized brassiere and provided follow-up consultations. A self-reported questionnaire on breast aesthetics, postoperative pain, and satisfaction was used to assess the primary outcomes. Data were prospectively collected at baseline (before surgery) and at 1, 3, 6, and 12 months after surgery and analyzed. Forty-six patients (50 breasts) were included in the analysis. Consistent wearing of the brassiere reduced pain (p<0.05), with good overall satisfaction (p<0.001). Aesthetic scores on breast shape and size were higher with than without the custom brassiere at 3 months (p=0.02) and 6 months (p=0.03) after surgery. Wearing the brassiere reduced anxiety at all time points of measurement. A well-fitting brassiere ensured safety and provided a high degree of satisfaction without anxiety for patients after breast reconstruction. |
| キーワード | breast reconstruction mastectomy brassiere professional bra fitter |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-02 |
| 巻 | 77巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 11 |
| 終了ページ | 19 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36849141 |
| Web of Science KeyUT | 000953663800002 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Ochi, Kosuke| Suzawa, Ken| Thu, Yin Min| Takatsu, Fumiaki| Tsudaka, Shimpei| Zhu, Yidan| Nakata, Kentaro| Takeda, Tatsuaki| Shien, Kazuhiko| Yamamoto, Hiromasa| Okazaki, Mikio| Sugimoto, Seiichiro| Shien, Tadahiko| Okamoto, Yoshiharu| Tomida, Shuta| Toyooka, Shinichi| |
| キーワード | cancer-associated fibroblast drug resistance tranilast |
| 発行日 | 2022-07-24 |
| 出版物タイトル | Cancer Science |
| 巻 | 2022巻 |
| 出版者 | Wiley |
| ISSN | 1347-9032 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35871750 |
| DOI | 10.1111/cas.15502 |
| Web of Science KeyUT | 000840374000001 |
| 関連URL | isVersionOf https://doi.org/10.1111/cas.15502 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Fujihara, Miwa| Shien, Tadahiko| Shien, Kazuhiko| Suzawa, Ken| Takeda, Tatsuaki| Zhu, Yidan| Mamori, Tomoka| Otani, Yusuke| Yoshioka, Ryo| Uno, Maya| Suzuki, Yoko| Abe, Yuko| Hatono, Minami| Tsukioki, Takahiro| Takahashi, Yuko| Kochi, Mariko| Iwamoto, Takayuki| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi| |
| キーワード | breast cancer YES1 T-DM1 dasatinib drug resistance |
| 発行日 | 2021-11-26 |
| 出版物タイトル | International Journal Of Molecular Sciences |
| 巻 | 22巻 |
| 号 | 23号 |
| 出版者 | MDPI |
| 開始ページ | 12809 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 34884609 |
| DOI | 10.3390/ijms222312809 |
| Web of Science KeyUT | 000735641400001 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms222312809 |
| JaLCDOI | 10.18926/AMO/60799 |
|---|---|
| フルテキストURL | 74_5_401.pdf |
| 著者 | Tsukioki, Takahiro| Shien, Tadahiko| Ohtani, Yusuke| Fujihara, Miwa| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| |
| 抄録 | Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC. |
| キーワード | differentiated thyroid carcinoma juvenile children |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-10 |
| 巻 | 74巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 401 |
| 終了ページ | 406 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33106695 |
| Web of Science KeyUT | 000581970100004 |
| NAID | 120006892925 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tsukioki, Takahiro| Shien, Tadahiko| Doihara, Hiroyoshi| |
| キーワード | Breast cancer metastatic stage IV local therapy locoregional therapy surgery survival |
| 発行日 | 2020-08 |
| 出版物タイトル | Translational Cancer Research |
| 巻 | 9巻 |
| 号 | 8号 |
| 出版者 | AME Publishing Co. |
| 開始ページ | 5102 |
| 終了ページ | 5107 |
| ISSN | 2218-676X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Translational Cancer Research. All rights reserved. |
| 論文のバージョン | publisher |
| DOI | 10.21037/tcr.2020.01.60 |
| Web of Science KeyUT | 000562138400067 |
| 関連URL | isVersionOf https://doi.org/10.21037/tcr.2020.01.60 |
| フルテキストURL | fulltext.pdf figure1.tif figure2.tif figure3.tif spfigure1.tif spfigure2.tif SupTable1.xlsx |
|---|---|
| 著者 | Ochi, Kosuke| Suzawa, Ken| Tomida, Shuta| Shien, Kazuhiko| Takano, Jui| Miyauchi, Shunsaku| Takeda, Tatsuaki| Miura, Akihiro| Araki, Kota| Nakata, Kentaro| Yamamoto, Hiromasa| Okazaki, Mikio| Sugimoto, Seiichiro| Shien, Tadahiko| Yamane, Masaomi| Azuma, Kazuo| Okamoto, Yoshiharu| Toyooka, Shinichi| |
| キーワード | Monensin Epithelial-mesenchymal transition Non-small cell lung cancer Drug repositioning Drug resistance |
| 備考 | This fulltext is available in Jul. 2021.| |
| 発行日 | 2020-08-27 |
| 出版物タイトル | Biochemical and Biophysical Research Communications |
| 巻 | 529巻 |
| 号 | 3号 |
| 出版者 | Academic Press |
| 開始ページ | 760 |
| 終了ページ | 765 |
| ISSN | 0006-291X |
| NCID | AA00564395 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 32736704 |
| DOI | 10.1016/j.bbrc.2020.06.077 |
| Web of Science KeyUT | 000555780500037 |
| 関連URL | iaVersionOf https://doi.org/10.1016/j.bbrc.2020.06.077 |