タイトル(別表記) | A case of immune checkpoint inhibitor-associated colitis treated with infliximab |
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著者 | 岩室 雅也| 平岡 佐規子| 大塚 基之| |
抄録 | A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary. |
キーワード | インフリキシマブ(infliximab) 免疫関連有害事象(immune-related adverse events) 大腸炎(colitis) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 69 |
終了ページ | 73 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.69 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.69 |
タイトル(別表記) | Metformin-induced mitochondrial reactive oxygen species and host defense mechanisms |
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著者 | 鵜殿 平一郎| |
キーワード | CD8T 細胞 活性酸素 Nrf2 解糖系 ミトコンドリア |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 63 |
終了ページ | 68 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.63 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.63 |
タイトル(別表記) | Five-year findings from the home blood pressure management study using IoT technology and future perspectives based on a time-series big data and AI analysis : the Masuda Study |
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著者 | 久松 隆史| 絹田 皆子| 福田 茉莉| 谷口 かおり| 中畑 典子| 神田 秀幸| |
キーワード | 家庭血圧(home blood pressure) IoT AI ビックデータ(big data) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 57 |
終了ページ | 62 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.57 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.57 |
タイトル(別表記) | The 2023 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2023 Sunada Prize) |
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著者 | 松原 慧| |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 54 |
終了ページ | 56 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.54 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.54 |
タイトル(別表記) | The 2023 Incentive Award of the Okayama Medical Association in Neuroscience (2023 Niimi Prize) |
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著者 | 藪野 諭| |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 51 |
終了ページ | 53 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.51 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.51 |
タイトル(別表記) | The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize) |
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著者 | 内藤 宏道| |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 48 |
終了ページ | 50 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.48 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.48 |
タイトル(別表記) | The 2023 Incentive Award of the Okayama Medical Association in Cancer Research (2023 Hayashibara Prize and Yamada Prize) |
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著者 | 石野 貴雅| |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2024-08-01 |
巻 | 136巻 |
号 | 2号 |
開始ページ | 45 |
終了ページ | 47 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.136.45 |
言語 | 日本語 |
著作権者 | Copyright (c) 2024 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.136.45 |
フルテキストURL | fulltext20240822-01.pdf |
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著者 | Kawase, Tomoka| Miura, Fumi| Debnath, Anusuya| Imakura, Kinuyo| Miyoshi, Shin-ichi| |
キーワード | Vibrio vulnificus Protease Propeptide Domain Cell-free translational system |
備考 | © 2018 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| |
発行日 | 2018-09 |
出版物タイトル | Protein Expression and Purification |
巻 | 149巻 |
出版者 | Elsevier BV |
開始ページ | 13 |
終了ページ | 16 |
ISSN | 1046-5928 |
NCID | AA10814149 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2018 Elsevier Inc. |
論文のバージョン | author |
PubMed ID | 29635038 |
DOI | 10.1016/j.pep.2018.04.004 |
Web of Science KeyUT | 000434003700003 |
関連URL | isVersionOf https://doi.org/10.1016/j.pep.2018.04.004 |
フルテキストURL | fulltext.pdf |
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著者 | Sumi, Tomonari| Harada, Kouji| |
キーワード | post-acute sequelae of SARS-CoV-2 infection PASC long Covid persistent viruses vaccine antiviral drug mathematical model immune response |
発行日 | 2024-08-09 |
出版物タイトル | Frontiers in Immunology |
巻 | 15巻 |
出版者 | Frontiers Media |
開始ページ | 1329162 |
ISSN | 1664-3224 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2024 Sumi and Harada. |
論文のバージョン | publisher |
PubMed ID | 39185419 |
DOI | 10.3389/fimmu.2024.1329162 |
Web of Science KeyUT | 001295899400001 |
関連URL | isVersionOf https://doi.org/10.3389/fimmu.2024.1329162 |
フルテキストURL | fulltext.pdf |
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著者 | Fukao, Takashi| Fujiwara, Masaki| Yamada, Yuto| Sakamoto, Shinji| Matsumoto, Yosuke| Takaki, Manabu| |
キーワード | anti-seizure medications attention-deficit/hyperactivity disorder electroencephalography transient epileptic amnesia |
発行日 | 2024-08-22 |
出版物タイトル | Psychiatry and Clinical Neurosciences Reports |
巻 | 3巻 |
号 | 3号 |
出版者 | Wiley |
開始ページ | e70003 |
ISSN | 2769-2558 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2024 The authors. |
論文のバージョン | publisher |
PubMed ID | 39184058 |
DOI | 10.1002/pcn5.70003 |
Web of Science KeyUT | 001295703300001 |
関連URL | isVersionOf https://doi.org/10.1002/pcn5.70003 |
フルテキストURL | fulltext.pdf |
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著者 | Ueda, Masataka| Tetsunaga, Tomoko| Tetsunaga, Tomonori| Nishida, Keiichiro| Takatori, Ryo| Shitozawa, Hisakazu| Uotani, Koji| Shinohara, Kennsuke| Oda, Yoshiaki| Ozaki, Toshifumi| |
キーワード | AIS cognitive-behavioral therapy EQ5D HADS insomnia pain-liaison outpatient clinic sleep disorders |
発行日 | 2024-08-09 |
出版物タイトル | Medicine |
巻 | 103巻 |
号 | 32号 |
出版者 | Lippincott, Williams & Wilkins |
開始ページ | e39113 |
ISSN | 0025-7974 |
NCID | AA00728867 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2024 the Author(s). |
論文のバージョン | publisher |
PubMed ID | 39121265 |
DOI | 10.1097/MD.0000000000039113 |
Web of Science KeyUT | 001287977800045 |
関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000039113 |
フルテキストURL | fulltext.pdf |
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著者 | Fujimoto, Takuya| Yamasaki, Osamu| Kanehira, Noriyuki| Matsushita, Hirokazu| Sakurai, Yoshinori| Kenmotsu, Naoya| Mizuta, Ryo| Kondo, Natsuko| Takata, Takushi| Kitamatsu, Mizuki| Igawa, Kazuyo| Fujimura, Atsushi| Otani, Yoshihiro| Shirakawa, Makoto| Shigeyasu, Kunitoshi| Teraishi, Fuminori| Togashi, Yosuke| Suzuki, Minoru| Fujiwara, Toshiyoshi| Michiue, Hiroyuki| |
キーワード | abscopal effect advanced melanoma boron neutron capture therapy boron-neutron immunotherapy immune combination therapy |
発行日 | 2024-08-09 |
出版物タイトル | Cancer Science |
出版者 | Wiley |
ISSN | 1347-9032 |
NCID | AA11808050 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2024 The Author(s). |
論文のバージョン | publisher |
PubMed ID | 39119813 |
DOI | 10.1111/cas.16298 |
Web of Science KeyUT | 001287521700001 |
関連URL | isVersionOf https://doi.org/10.1111/cas.16298 |
JaLCDOI | 10.18926/AMO/67554 |
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フルテキストURL | 78_4_349.pdf |
著者 | Tominaga, Yuichiro| Sugaya, Akiko| Kariya, Shin| Shimizu, Aiko| Kataoka, Yuko| Ando, Mizuo| |
抄録 | Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment. |
キーワード | middle-ear salivary gland choristoma middle-ear morphological abnormalities newborn hearing screening unilateral hearing loss surgical resection |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2024-08 |
巻 | 78巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 349 |
終了ページ | 355 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
JaLCDOI | 10.18926/AMO/67553 |
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フルテキストURL | 78_4_345.pdf |
著者 | Kato, Gentaro| Narumiya, Yuto| Okuyama, Michihiro| Shimizu, Shuji| Sangawa, Kenji| Yamamoto, Shu| |
抄録 | The presence of an intraperitoneal source of infection, e.g., a liver abscess, can be an obstacle to performing an abdominal aortic surgery with a midline laparotomy because graft infection is one of the most critical complications of aortic surgery. We report the successful Y-grafting of a pararenal abdominal aortic aneurysm through a retroperitoneal approach in a 67-year-old male undergoing liver abscess drainage. The retroperitoneal approach to the abdominal aorta may be useful for abdominal aortic surgery in patients with a localized intraperitoneal infection. |
キーワード | blunt liver trauma liver abscess abdominal aortic aneurysm Y-grafting retroperitoneal approach |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2024-08 |
巻 | 78巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 345 |
終了ページ | 347 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
著者 | Matsumoto, Naomi| Sasaki, Ayako| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Takao, Soshi| Yorifuji, Takashi| |
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キーワード | SARS-CoV-2 Vaccine Antibody Mixed-effects model Omicron |
備考 | © 2024 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Aug. 2025.| |
発行日 | 2024-08 |
出版物タイトル | Vaccine |
巻 | 42巻 |
号 | 21号 |
出版者 | Elsevier BV |
開始ページ | 126156 |
ISSN | 0264-410X |
NCID | AA10491877 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2024 Elsevier Ltd. |
論文のバージョン | author |
PubMed ID | 39088986 |
DOI | 10.1016/j.vaccine.2024.126156 |
Web of Science KeyUT | 001285745600001 |
関連URL | isVersionOf https://doi.org/10.1016/j.vaccine.2024.126156 |
フルテキストURL | fulltext.pdf |
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著者 | Ooba, Hikaru| Maki, Jota| Masuyama, Hisashi| |
キーワード | Labor duration Trial of labor after cesarean section Vaginal birth Cesarean section Propensity scores IPTW |
発行日 | 2024-08-15 |
出版物タイトル | BMC Pregnancy and Childbirth |
巻 | 24巻 |
号 | 1号 |
出版者 | BMC |
開始ページ | 542 |
ISSN | 1471-2393 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2024. |
論文のバージョン | publisher |
PubMed ID | 39148014 |
DOI | 10.1186/s12884-024-06744-0 |
Web of Science KeyUT | 001291316100002 |
関連URL | isVersionOf https://doi.org/10.1186/s12884-024-06744-0 |
JaLCDOI | 10.18926/AMO/67550 |
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フルテキストURL | 78_4_337.pdf |
著者 | Makihara, Seiichiro| Otani, Yoshihiro| Uraguchi, Kensuke| Ono, Sawako| Shimizu, Aiko| Ikemachi, Ryosuke| Okazaki, Yosuke| Ota, Tomoyuki| Matsumoto, Hiroshi| Miyamoto, Shotaro| Tsumura, Munechika| Hayashi, Seiya| Umakoshi, Michiari| Hirashita, Koji| Ando, Mizuo| |
抄録 | Here, we describe the unique case of a pneumocephalus originating from an inverted papilloma (IP) in the frontoethmoidal sinus. A 71-year-old man with diabetes presented with headaches and altered consciousness. Imaging revealed the pneumocephalus together with bone destruction in the left frontal sinus. He underwent simultaneous endoscopic endonasal and transcranial surgery using an ORBEYE exoscope. Pathological diagnosis of the tumor confirmed IP. Post-surgery, the pneumocephalus was significantly resolved and the squamous cell carcinoma antigen level, which had been elevated, decreased. This case underscores the importance of a multidisciplinary approach and innovative surgical methods in treating complex sinonasal pathologies. |
キーワード | pneumocephalus inverted papilloma frontoethmoidal sinus endoscopic endonasal and transcranial surgery |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2024-08 |
巻 | 78巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 337 |
終了ページ | 343 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
JaLCDOI | 10.18926/AMO/67549 |
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フルテキストURL | 78_4_331.pdf |
著者 | Furukawa, Chieko| Tachibana, Tomoyasu| Nobuhisa, Tetsuji| Kanie, Yuichiro| Wani, Yoji| Matsumoto, Jun-Ya| Kariya, Akifumi| Sato, Asuka| Ishikawa, Iichiro| Naoi, Yuto| Ando, Mizuo| |
抄録 | No previous study has published magnetic resonance imaging (MRI) findings for a subglottic pleomorphic adenoma. Here, we describe the case of a 62-year-old man with a subglottic pleomorphic adenoma. Endoscopic findings revealed a smooth-surfaced tumor arising from the subglottic posterior wall. MRI revealed the lesion as an isointense region on T1-weighted images, which was homogeneously enhanced. This lesion showed a heterogeneously hyperintense region on T2-weighted images. Diffusion-weighted imaging (DWI) showed slightly high intensity in the same area, with a normal or only slightly high apparent diffusion coefficient (ADC). Laryngomicrosurgery was performed for transoral excision of the subglottic tumor, resulting in a postsurgical diagnosis of pleomorphic adenoma. |
キーワード | subglottis pleomorphic adenoma MRI transoral surgery |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2024-08 |
巻 | 78巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 331 |
終了ページ | 335 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
JaLCDOI | 10.18926/AMO/67548 |
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フルテキストURL | 78_4_323.pdf |
著者 | Katayama, Akira| Kimura, Satoshi| Matsusaki, Takashi| Morimatsu, Hiroshi| |
抄録 | It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications. |
キーワード | pediatric liver transplantation postoperative severe complications Graft-to-Recipient Weight Ratio |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2024-08 |
巻 | 78巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 323 |
終了ページ | 330 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
JaLCDOI | 10.18926/AMO/67547 |
---|---|
フルテキストURL | 78_4_313.pdf |
著者 | Eto, Eriko| Maki, Jota| Yamashita, Noriyuki| Hasegawa, Toru| Suemori, Ayano| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Kirino, Satoe| Ohira, Akiko| Masuyama, Hisashi| |
抄録 | During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku–Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable. |
キーワード | remote simulator education perinatal simulator information and communication technology high-flexibility education |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2024-08 |
巻 | 78巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 313 |
終了ページ | 322 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |