The subendothelial circulatory system in the splenic trabecular vein and the intrasplenic cell recurrence.

In the spleen of patient exposed to atomic bomb as well as in the infective spleen and leukemic spleen sometimes characteristic endothelium of the trabecular vein can be observed and this canalicula in the trabecular vein communicates with reticulum tissue of the pulp. In the subendothelial circulatory canalicula of the splenic trabecular vein there can be observed emigrating picture of various leucocytes of the vein passing this subendothelium (chemotaxisis) and these cells emigrate and accumulate outside the splenic trabecula (intrasplenic cell recurrence). Arterial blood circulates in these subendothelial canaliculae and these canaliculae are not lymph canaliculae as demonstrated by JAGER and ROSSLE. Many leucocytes flow back into the pulp outside the trabecula through this circulatory system. Also in the peritrabecular pulp a new formation of collagen fibers and a considerable number of plasma cells can be observed in various infective spleens, and splenic trabecular area is the regenerating center and reactive center in the spleen, just as lymph follicle in the spleen.