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ID 19784
Eprint ID
19784
フルテキストURL
Thumnail 68_1415.pdf 896 KB
タイトル(別表記)
Fundamental and Clinical Studies on Medical Treatment of Moniliasis with Photosensitizing Dyes. Part. Ⅰ The relation between constitutional formulas of photosensitizing dyes and anticandida action and influences of photosensitizing dye NK 91 upon Candida albicans
著者
山口 義雄 岡山大学医学部平木内科教室
抄録
The author has investigated a specific fungiostatic action against Candida albicans Tanimoto by using 109 different species of photosensitizing dyes, classifing them into groups according to their constitutional formulas. Among so many species photosensitizing dye NK 91 which belongs to Styril type showed the strongest fungiostatic action and scareely decreased its effect by adding serum. The results obtained can be summarized as follows: 1) In respect of the types of dyes, Monomethin, Trimethin, Heptamethin, Cyanin and Styril types showed a strong fungiostatic action. 2) In respect of the radical nucleus (of dyes, Benzothiazol. Naphtothiazol and Chinorin nucleus showed a moderate fungiostatic action). 3) In respect of the alkyl radical, high alkyl did not always show the fungiostatic effect. 4) In regard to Halogen and acid radical, eight kinds of iodine radical, one kind of bromine radical, and three kinds of acid radical were efficacious. 5) NK 91 changed remarkably the shape of Candida albicans and moreover in the high concentration, perished utterly Candida albicans. 6) NK 91 inhibited the decline of pH of Sabouraud-glucose medium in which Candida albicans was inoculated. 7) The respiration of Candida albicans was inhibited and its oxygen consumption lowered by NK 91.
発行日
1956-09-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
68巻
9号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1415
終了ページ
1427
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/68/9/68_9_1415/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma