ID | 16339 |
Eprint ID | 16339
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フルテキストURL | |
タイトル(別表記) | Studies on antigens of a leukemic null-cell line (NALL-1)II. A leukemia-lymphoma associated antigen detected by rabbit anti-NALL-1 serum.
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著者 |
宇野 順三郎
岡山大学医学部第2内科学教室
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抄録 | Rabbit antiserum was raised against leukemic null-cell line, NALL-1. After absorptions with normal human red blood cells, normal human liver cells and established leukemic T-cells (TALL-1) and B-cells (BALL-1), the antiserum reacted specifically with leukemic null-cell lines (NALL-1, KOPN-1, KOPN-8 and AL-6), but not with cells of TALL-1, BALL-1 and an acute promyelocytic leukemic cell line (HL-60). This absorbed anti-NALL-1 serum also reacted with 9 out of 12 null-acute lymphoblastic leukemia cells, 4 of 10 chronic myelogenous leukemia cells in blastic crisis and 2 of 4 null-non-Hodgkin's lymphoma cells, but not with other leukemic cells. The reactivities of the antiserum against normal peripheral blood mononuclear cells and PHA-stimulated blasts were less than 5%. These results indicate that the antigen defined by the absorbed anti-NALL-1 serum is a null-cell type leukemia-lymphoma associated antigen, but not a specific one. Thus the antiserum is a useful marker for the diagosis of null-cell type leukemia and lymphoma.
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キーワード | Null-cell白血病細胞株(NALL-1)
白血病関連抗原
家兎抗ALL血清
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発行日 | 1983-08-31
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 95巻
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号 | 7-8号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 643
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終了ページ | 652
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/95/7-8/95_7-8_643/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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言語 |
日本語
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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