ID | 14017 |
Eprint ID | 14017
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フルテキストURL | |
タイトル(別表記) | Clinical studies on hypoplastic anemia in the aged
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著者 |
植田 育寛
岡山大学医学部第二内科学教室
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抄録 | To evaluate hypoplastic anemia (HA) in the aged, clinical and hematological findings of 88 patients with HA were analyzed. The patients were classified into 4 groups according to age (Group A : 5-24 y/o, Group B : 25-44 y/o, Group C : 45-64 y/o and Group D : 65 y/o- ). Hematological findings of patients in Group D were also compared to those of aged patients (above 65 y/o) with myelodisplastic syndrome (MDS) to clarify differentiation of HA from MDS. Items studied were severity, therapeutic response, complications, hematological findings, survival period and cause of death. The following results were obtained :
1. HA in the aged was frequently severe.
2. Responses to therapies including anabolic steroids and corticosteroids tended to be poor in the aged compared to those in younger patients.
3. Infections and diabetes mellitus were frequently observed complications in the aged.
4. Mortality in the aged was higher than that in younger patients. 57.1% of the aged died from bleeding.
5. The survival period of patients in Group C and D was shorter than that of patients in Group A and B.
6. Red blood cell count, reticulocytes and hemoglobin level in the aged were significantly lower than those in younger patients. Neutrophil and monocyte counts in the aged tended to be lower than those in younger patients. Nucleated cell counts and percentages of granulocytes and erythroblasts in the marrow were also lower in the aged.
7. The incidence of atypical hematological findings in HA were not different between the aged and younger patients.
8. In a comparison of HA in Group D and MDS in the aged, patients with HA showed severe anemia and thrombocytopenia.
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キーワード | 再生不良性貧血
高齢者貧血
骨髄異形成症候群
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発行日 | 1993
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 105巻
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号 | 3-4号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 265
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終了ページ | 279
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/105/3-4/105_3-4_265/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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言語 |
日本語
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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