Studies on Metabolism of Acinomycetes and Assay Method with Microoganism

The　microorganisms belonging to actinomycetes been important as the antibiotic producers and my major job has been a screening for useful new antibiotics produced by a actinomycete almost in my reseach.My collaborators and I found nineteen new antibiotics between 1956 and 1980 and thereafter three antibiotics particululy (Enramycin-feed additive,Validamycin-agriculture use,effective against the seach blight disease of rice plants,Ssdecamycin-effective agaist swine dysenteriae)were developed for industrial production and become useful for many people.And also we were interrested in those chemical structres and activities,fermentation processes by mutants or producing organsums namely rufomycins,maridomycins and ansamitocins.And from another point a new assay method for the activities of disinfectants was epoch making invesitgation.