REPO

Annual Reports of Misasa Medical Center, Okayama University volume67
1996-11 発行

気管支喘息に対する複合温泉療法の作用機序 3.気道炎症反応との関連

Hosaki, Yasuhiro
Mifune, Takashi
Mitsunobu, Fumihiro Kaken ID publons researchmap
Ashida, Kozo Kaken ID researchmap
Yokota, Satoshi
Tsugeno, Hirofumi
Takeuchi, Kazuaki
Nawa, Yuichiro
Tanizaki, Yoshiro
Ochi, Koji
Harada, Hideo
Publication Date
1996-11
Abstract
The degree and characteristic of airway inflammation were evaluated by the proportions of bronchoalveolar lavage (BAL) cells. Clinical asthma types such as Ia. simple bronchoconstriction, Ib. bronchoconstriction + hypersecretion, and Ⅱ. bronchiolar obstruction correlate with airway inflammation. The increased proportion BAL neutrophils is characteristic of type Ⅱ asthma, and increase in BAL eosinophil count is often observed in type Ib asthma. Bronchial hyperresponsiveness also correlates with airway inflammation. Action of spa therapy has been speculated to be related to airway inflammation, since the therapy has no action inhibiting IgE-mediated allergic reaction. In fact, spa therapy is more effective in patients with type Ib and type Ⅱ than in those with type Ia showing slight degree of airway inflammation. Bronchial hyperresponsiveness is also improved by spa therapy. From a point of view, the direct action of spa therapy may be to clean airways and improve damaged mucous membrane of the airways, leading to suppression of airway inflammation.
Keywords
Spa therapy (温泉療法)
Airway inflammation (気道炎症反応)
BAL eosinophilia (BAL好酸球増多)
BAL neutrophilia (BAL好中球増多)
Bronchial asthma (気管支喘息)
ISSN
0918-7839
NCID
AN10430852
NAID