Journal of Okayama Medical Association
Published by Okayama Medical Association

<Availability>
Full-text articles are available 3 years after publication.

散発性A型肝炎の臨床像 ―その臨床症状,経過と予後について―

Fukuda, Tetsuya
Yamada, Gotaro
Ogawa, Hiromichi
Okushin, Hiroaki
Hyodo, Ichinosuke
Nishihara, Takashi
Mizuno, Motowo
Sakamoto, Yuji
Nagashima, Hideo
Kobayashi, Toshinari
Yoshida, Tomoro
96_305.pdf 422 KB
Abstract
Clinical and laboratory features of 66 patients with sporadic hepatitis A were evaluated from October 1978 to July 1981. Jaundice was reported in 88.6% of the patients, and the frequency of skin rash was 15.7%. Less than 5% atypical lymphocytes were noted in 29.5% of the patients. Proteinuria and hematuria were present in 23.4% and 6.3% of the patients. However, immune complexes were not detected in their sera. One of the patients who had hematuria developed acute renal failure. About 10% of the patients transiently showed both low levels of cholinesterase and cholesterol and prolongation of the prothrombin time. There was no patient with fulminant hepatic failure. Liver function tests returned to normal except for 3 patients within 3 months. For 10 months after the onset, slight elevation of SGPT peristed in the patient with acute renal failure and also in a patients with a previous history of liver disease. One of two patients with acute intrahepatic cholestasis showed protraction of mild hyperbilirubinemia more than 6 months after the onset of acute illness.
Keywords
散発性A型肝炎
免疫複合体
重症化
遷延化
ISSN
0030-1558
NCID
AN00032489