To frog sperms high hydrostatic pressure up to 1500kg/c㎡ was applied, and following changes were observed. (1) The motility of sperms does not change at under 1000 kg/c㎡ pressure, but at higher pressure they become inactive or immotile. (2) At certain high pressure some sperms have their motility but lose fertility. (3) Frog eggs are affected by high pressure more sensitively than sperms.