Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

脳のglucose代謝におよぼすamino酸の影響に関する研究 第1編 潜在性脳局所anaphylaxis家兎大脳皮質のglucose代謝およびそれにおよぼす種々のamino酸の影響について

Yamamoto, Yasuhisa
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There are many kinds of free amino-acids in the brain, most of which are glutamic acid, glutamine, asparatic acid. asparagine, γ-aminobutyric acid etc. The author has investigated the influences of these amino-acids upon the glucose metabolism in the brain of the normal and the cerebral local anaphylactic (C. L. A.) rabbits. Glutamic acid, glutamine and γ-aminobutyric acid accelerate the utilization of glucose in the brain of the normal as well as the C. L. A. rabbits, aspartic acid and asparagine accelerate that of glucose in the C. L. A. rabbits, while they have no influence on that in the normal. It is clarified that all of these amino-acids have the function to restore the decreased utilization of glucose in the C. L. A. rabbits to more than the normal level.