Studies on coagulating time and serum bactericidal action of arterial and venous blood. Part 2. Experimental studies on the significance of the difference of the coagulating time between the arterial and venous blood in dogs

1) As far as the number of the blood platelets is concerned, neither significant difference is observed between the carotid arterv and jugular vein, nor between the pulmonary artery and pulmonary vein, while the platelet number of the blood of the femoral vein is smaller than that of the femoral artery. On the other hand, the blood of the hepatic vein and portal vein contained a greater number of platelets than that of any other blood vessel. 2) The serum prothrombin time of the blood of the carotid, femoral and pulmonary arteries is a little shorter than that of the corresponding veins respectively. Those of the hepatic and portal veins are shorter than those of other vessels. The various organs and tissues of the hepato-portal system are thought to play an important role in production of prothrombin. 3) The serum calcium contents of the blood of various vessels show no significant differences. 4) As for amount of thrombin in the serum, the blood of the femoral and pulmonary arteries contains greater amount than that of the femoral and pulmonary vein respectively, The thrombin content of the hepatic and portal veins is still greater. 5) As far as the amount of serum fibrinogen is concerned, the carotid arterial blood and the pulmonary arterial blood show a greater value than the corresponding venous blood respectively. The blood of the hepatic and portal vein presents still greater estimate. 6) The amount of plasma protein shows no significant difference between various arteries and veins, although those of hepatic and portalveins give a slightly greater values than those of the other vessels. 7) The blood sugar values of the femoral and pulmonary arterial blood are slightly greater than those of the femoral and pulmonary venous blood respectively. 8) The phenomenon of fibrinolysis occurrs strongly in the blood of the femoral vein, while it occurrs more weakly in the blood of hepatic and portal veins compared with other blood vessels. 9) The number of blood platelets and the amount of prothrombin, thrombin, fibrinogen, serum protein and fibrinolysin have some relation respectively to the fact that the coagulating time of the blood of the carotid, pulmonary and femorary arteries is shorter than that of the corresponding veins respectively and that of the blood of the hepatic and portal veins is much shorter. Particularly the amounts of prothrombin, thrombin and fibrinogen are seen to play an important role.