検索結果 - 岡山大学学術成果リポジトリ

Effective division of the intersegmental plane using a robotic stapler in robotic pulmonary segmentectomy

フルテキストURL	fulltext.pdf
著者	Okazaki, Mikio\| Suzawa, Ken\| Shien, Kazuhiko\| Hashimoto, Kohei\| Tanaka, Shin\| Miyoshi, Kentaroh\| Yamamoto, Hiromasa\| Sugimoto, Seiichiro\| Toyooka, Shinichi\|
キーワード	Pulmonary segmentectomy Robot-assisted thoracic surgery Robotic segmentectomy Robotic stapler
備考	The version of record of this article, first published in Surgery Today, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00595-024-02840-y\|
発行日	2024-04-18
出版物タイトル	Surgery Today
巻	54巻
号	11号
出版者	Springer Science and Business Media LLC
開始ページ	1319
終了ページ	1328
ISSN	0941-1291
NCID	AA10824685
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	38635055
DOI	10.1007/s00595-024-02840-y
Web of Science KeyUT	001205481400002
関連URL	isVersionOf https://doi.org/10.1007/s00595-024-02840-y

Prognostic impact of adjuvant endocrine therapy for estrogen receptor-positive and HER2-negative T1a/bN0M0 breast cancer

フルテキストURL	fulltext.pdf
著者	Sasada, Shinsuke\| Kondo, Naoto\| Hashimoto, Hiroya\| Takahashi, Yuko\| Terata, Kaori\| Kida, Kumiko\| Sagara, Yasuaki\| Ueno, Takayuki\| Anan, Keisei\| Suto, Akihiko\| Kanbayashi, Chizuko\| Takahashi, Mina\| Nakamura, Rikiya\| Ishiba, Toshiyuki\| Tsuneizumi, Michiko\| Nishimura, Seiichiro\| Naito, Yoichi\| Hara, Fumikata\| Shien, Tadahiko\| Iwata, Hiroji\|
キーワード	Breast cancer T1a/b Endocrine therapy Estrogen receptor Prognosis
備考	The version of record of this article, first published in Breast Cancer Research and Treatment, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10549-023-07097-6\|
発行日	2023-09-09
出版物タイトル	Breast Cancer Research and Treatment
巻	202巻
号	3号
出版者	Springer Science and Business Media LLC
開始ページ	473
終了ページ	483
ISSN	0167-6806
NCID	AA10623184
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37688665
DOI	10.1007/s10549-023-07097-6
Web of Science KeyUT	001065105700004
関連URL	isVersionOf https://doi.org/10.1007/s10549-023-07097-6

Postoperative Complications in Living Donors for Lung Transplantation

フルテキストURL	fulltext.pdf
著者	Tanaka, Shin\| Fujii, Kento\| Ishihara, Megumi\| Choshi, Haruki\| Matsubara, Kei\| Hashimoto, Kohei\| Okahara, Shuji\| Shien, Kazuhiko\| Suzawa, Ken\| Miyoshi, Kentaroh\| Yamamoto, Hiromasa\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Toyooka, Shinichi\|
発行日	2024-05
出版物タイトル	Transplantation Direct
巻	10巻
号	5号
出版者	Lippincott, Williams & Wilkins
開始ページ	e1617
ISSN	2373-8731
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Author(s).
論文のバージョン	publisher
PubMed ID	38606350
DOI	10.1097/TXD.0000000000001617
Web of Science KeyUT	001198793600003
関連URL	isVersionOf https://doi.org/10.1097/TXD.0000000000001617

Outcomes of solitary postoperative recurrence of esophageal squamous cell carcinoma diagnosed with FDG-PET/CT and treated with definitive radiation therapy

フルテキストURL	fulltext.pdf
著者	Ihara, Hiroki\| Yoshio, Kotaro\| Tanabe, Shunsuke\| Sugiyama, Soichi\| Hashimoto, Masashi\| Maeda, Naoaki\| Akagi, Shinsuke\| Takao, Soshi\| Noma, Kazuhiro\| Hiraki, Takao\|
キーワード	Radiation therapy Esophageal squamous cell carcinoma Recurrence 18F-fluorodeoxyglucose positron emission tomography Survival
備考	The version of record of this article, first published in Esophagus, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10388-023-01000-4\|
発行日	2023-04-07
出版物タイトル	Esophagus
巻	20巻
号	3号
出版者	Springer Science and Business Media LLC
開始ページ	548
終了ページ	556
ISSN	1612-9059
NCID	AA11885266
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37027045
DOI	10.1007/s10388-023-01000-4
Web of Science KeyUT	000964113700001
関連URL	isVersionOf https://doi.org/10.1007/s10388-023-01000-4

p53-Armed Oncolytic Virotherapy Improves Radiosensitivity in Soft-Tissue Sarcoma by Suppressing BCL-xL Expression

JaLCDOI	10.18926/AMO/66924
フルテキストURL	78_2_151.pdf
著者	Komatsubara, Tadashi\| Tazawa, Hiroshi\| Hasei, Joe\| Omori, Toshinori\| Sugiu, Kazuhisa\| Mochizuki, Yusuke\| Demiya, Koji\| Yoshida, Aki\| Fujiwara, Tomohiro\| Kunisada, Toshiyuki\| Urata, Yasuo\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
抄録	Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly from the embryonic mesoderm. Despite the development of combined modalities including radiotherapy, STSs are often refractory to antitumor modalities, and novel strategies that improve the prognosis of STS patients are needed. We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells. Here, we demonstrate in vitro and in vivo antitumor effects of OBP-702 in combination with ionizing radiation against human STS cells (HT1080, NMS-2, SYO-1). OBP-702 synergistically promoted the antitumor effect of ionizing radiation in the STS cells by suppressing the expression of B-cell lymphoma-X large (BCL-xL) and enhancing ionizing radiation-induced apoptosis. The in vivo experiments demonstrated that this combination therapy significantly suppressed STS tumors’ growth. Our results suggest that OBP-702 is a promising antitumor reagent for promoting the radiosensitivity of STS tumors.
キーワード	soft-tissue sarcoma radiotherapy oncolytic adenovirus p53 BCL-xL
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	151
終了ページ	161
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688833
Web of Science KeyUT	001229151800007

Sigle Agent of Posttransplant Cyclophosphamide Without Calcineurin Inhibitor Controls Severity of Experimental Chronic GVHD

JaLCDOI	10.18926/AMO/66915
フルテキストURL	78_2_123.pdf
著者	Saeki, Kyosuke\| Fujiwara, Hideaki\| Seike, Keisuke\| Kuroi, Taiga\| Nishimori, Hisakazu\| Tanaka, Takehiro\| Matsuoka, Ken-ichi\| Fujii, Nobuharu\| Maeda, Yoshinobu\|
抄録	Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT.
キーワード	GVHD posttransplant cyclophosphamide hematopoietic cell transplantation HLA-identical
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	123
終了ページ	134
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688830
Web of Science KeyUT	001229151800004

The Roles of Neuropeptide Y in Respiratory Disease Pathogenesis via the Airway Immune Response

JaLCDOI	10.18926/AMO/66912
フルテキストURL	78_2_095.pdf
著者	Itano, Junko\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
抄録	The lungs are very complex organs, and the respiratory system performs the dual roles of repairing tissue while protecting against infection from various environmental stimuli. Persistent external irritation disrupts the immune responses of tissues and cells in the respiratory system, ultimately leading to respiratory disease. Neuropeptide Y (NPY) is a 36-amino-acid polypeptide and a neurotransmitter that regulates homeostasis. The NPY receptor is a seven-transmembrane-domain G-protein-coupled receptor with six subtypes (Y1, Y2, Y3, Y4, Y5, and Y6). Of these receptors, Y1, Y2, Y4, and Y5 are functional in humans, and Y1 plays important roles in the immune responses of many organs, including the respiratory system. NPY and the Y1 receptor have critical roles in the pathogenesis of asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. The effects of NPY on the airway immune response and pathogenesis differ among respiratory diseases. This review focuses on the involvement of NPY in the airway immune response and pathogenesis of various respiratory diseases.
キーワード	neuropeptide y Y1 receptor airway immune response bronchial epithelial cells respiratory disease
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	95
終了ページ	106
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688827
Web of Science KeyUT	001229151800001

Oxygen-evolving photosystem II structures during S1–S2–S3 transitions

フルテキストURL	fulltext.pdf
著者	Li, Hongjie\| Nakajima, Yoshiki\| Nango, Eriko\| Owada, Shigeki\| Yamada, Daichi\| Hashimoto, Kana\| Luo, Fangjia\| Tanaka, Rie\| Akita, Fusamichi\| Kato, Koji\| Kang, Jungmin\| Saitoh, Yasunori\| Kishi, Shunpei\| Yu, Huaxin\| Matsubara, Naoki\| Fujii, Hajime\| Sugahara, Michihiro\| Suzuki, Mamoru\| Masuda, Tetsuya\| Kimura, Tetsunari\| Thao, Tran Nguyen\| Yonekura, Shinichiro\| Yu, Long-Jiang\| Tosha, Takehiko\| Tono, Kensuke\| Joti, Yasumasa\| Hatsui, Takaki\| Yabashi, Makina\| Kubo, Minoru\| Iwata, So\| Isobe, Hiroshi\| Yamaguchi, Kizashi\| Suga, Michihiro\| Shen, Jian-Ren\|
備考	The version of record of this article, first published in Nature, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41586-023-06987-5\|
発行日	2024-01-31
出版物タイトル	Nature
巻	626巻
号	7999号
出版者	Springer Science and Business Media LLC
開始ページ	670
終了ページ	677
ISSN	0028-0836
NCID	AA00752384
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	38297122
DOI	10.1038/s41586-023-06987-5
Web of Science KeyUT	001179152900004
関連URL	isVersionOf https://doi.org/10.1038/s41586-023-06987-5

Long-term activation of anti-tumor immunity in pancreatic cancer by a p53-expressing telomerase-specific oncolytic adenovirus

フルテキストURL	fulltext20240219-05.pdf
著者	Hashimoto, Masashi\| Kuroda, Shinji\| Kanaya, Nobuhiko\| Kadowaki, Daisuke\| Yoshida, Yusuke\| Sakamoto, Masaki\| Hamada, Yuki\| Sugimoto, Ryoma\| Yagi, Chiaki\| Ohtani, Tomoko\| Kumon, Kento\| Kakiuchi, Yoshihiko\| Yasui, Kazuya\| Kikuchi, Satoru\| Yoshida, Ryuichi\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Yagi, Takahito\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
備考	The version of record of this article, first published in British Journal of Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41416-024-02583-0\|
発行日	2024-02-05
出版物タイトル	British Journal of Cancer
巻	130巻
号	7号
出版者	Springer Science and Business Media LLC
開始ページ	1187
終了ページ	1195
ISSN	0007-0920
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	38316993
DOI	10.1038/s41416-024-02583-0
Web of Science KeyUT	001156904400001
関連URL	isVersionOf https://doi.org/10.1038/s41416-024-02583-0

Bundling of collagen fibrils influences osteocyte network formation during bone modeling

フルテキストURL	fulltext.pdf
著者	Hashimoto, Mana\| Takahashi, Haruka\| Tabata-Okubo, Kaori\| Nagaoka, Noriyuki\| Tokunaga, Kazuaki\| Matsumori, Haruka\| Ishihara, Yoshihito\| Kaku, Masaru\| Iimura, Tadahiro\| Hara, Toru\| Kamioka, Hiroshi\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-48786-y\|
発行日	2023-12-12
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	22028
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	38086873
DOI	10.1038/s41598-023-48786-y
Web of Science KeyUT	001126179100035
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-48786-y

Photoelectron holographic evidence for the incorporation site of Se and suppressed atomic displacement of the conducting layer of La(O,F)BiSSe

フルテキストURL	fulltext20231221-02.pdf
著者	Li, YaJun\| Sun, ZeXu\| Kataoka, Noriyuki\| Setoguchi, Taro\| Hashimoto, Yusuke\| Takeuchi, Soichiro\| Koga, Shunjo\| Hoshi, Kazuhisa\| Mizuguchi, Yoshikazu\| Matsushita, Tomohiro\| Wakita, Takanori\| Muraoka, Yuji\| Yokoya, Takayoshi\|
キーワード	photoelectron holography La(O,F)BiS2-x Se x local structure dopant site
備考	This is the Accepted Manuscript version of an article accepted for publication in Japanese Journal of Applied Physics. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.35848/1347-4065/ad079b.\| This fulltext file will be available in Nov. 2024.\|
発行日	2023-11-21
出版物タイトル	Japanese Journal of Applied Physics
巻	62巻
号	12号
出版者	IOP Publishing
開始ページ	125001
ISSN	0021-4922
NCID	AA12295836
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Japan Society of Applied Physics
論文のバージョン	author
DOI	10.35848/1347-4065/ad079b
Web of Science KeyUT	001108061600001
関連URL	isVersionOf https://doi.org/10.35848/1347-4065/ad079b

Effects of Nutritional Support Combined with Neuromuscular Electrical Stimulation on Muscle Strength and Thickness: A Randomized Controlled Trial in Healthy Young Adult Males

JaLCDOI	10.18926/AMO/66156
フルテキストURL	77_6_635.pdf
著者	Ikeda, Tomohiro\| Okamura, Kazunori\| Hasegawa, Masaki\| Tanaka, Satoshi\| Kanai, Shusaku\|
抄録	In the management of post-injury patients with activity limitations, methods to prevent musculoskeletal disorders and hasten recovery are important. This randomized controlled, single-blinded study was a preliminary investigation of the combined effect of nutritional support with neuromuscular electrical stimulation (NMES) on muscle strength and thickness. Healthy young adult males (median age, 21 years) were enrolled; each of their hands was randomly assigned to one of the following four groups: Placebo, Nutrition, NMES, and Nutrition + NMES. All participants received whey protein or placebo (3x/week for 6 weeks) and NMES training (3x/week for 6 weeks) on the abductor digiti minimi (ADM) muscle of either the left or right hand. ADM muscle strength and thickness were analyzed at baseline and at week 7. We analyzed 38 hands (9 Placebo, 10 Nutrition, 9 NMES, 10 Nutrition + NMES). There was significantly greater muscle strengthening in the Nutrition + NMES group compared to the Placebo group or the NMES group, but no significant difference in gain of muscle thickness. The combined intervention may be effective in improving muscle strength. Future clinical trials targeting various muscles after sports-related injuries are warranted.
キーワード	whey protein electrical stimulation muscle strength healthy volunteers
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-12
巻	77巻
号	6号
出版者	Okayama University Medical School
開始ページ	635
終了ページ	645
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38145938
Web of Science KeyUT	001164631200009

Endoscopic Manifestations and Clinical Characteristics of Localized Gastric Light-Chain Amyloidosis

JaLCDOI	10.18926/AMO/65978
フルテキストURL	77_5_545.pdf
著者	Iwamuro, Masaya\| Tanaka, Shouichi\| Toyokawa, Tatsuya\| Nishimura, Mamoru\| Tsuzuki, Takao\| Miyahara, Koji\| Negishi, Shin\| Ohya, Shogen\| Tanaka, Takehiro\| Otsuka, Motoyuki\|
抄録	To determine the endoscopic and clinical features of localized gastric amyloid light-chain (AL) amyloidosis, we retrospectively examined the characteristics of nine patients (eight men and one woman) encountered by the hospitals in our network. Lesions were predominantly flat and depressed with surface vascular dilatation (n=5); others were characterized by subepithelial lesions (n=2), mucosal color change (n=1), and a mass-like morphology with swollen mucosal folds (n=1). Colonoscopy (n=7), video capsule enteroscopy (n=2), serum (n=5) and urine immunoelectrophoresis (n=4), and bone marrow examination (n=3) were performed to exclude involvement of organs other than the stomach. As treatment for gastric lesions of AL amyloidosis, one patient each underwent endoscopic submucosal dissection (n=1) and argon plasma coagulation (n=1), while the remaining seven patients underwent no specific treatment. During a mean follow-up of 4.2 years, one patient died 3.2 years after diagnosis, but the cause of death, which occurred in another hospital, was unknown. The remaining eight patients were alive at the last visit. In conclusion, although localized gastric AL amyloidosis can show various macroscopic features on esophagogastroduodenoscopy, flat, depressed lesions with vascular dilatation on the surface are predominant.
キーワード	esophagogastroduodenoscopy gastric lesion amyloidosis light chain
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-10
巻	77巻
号	5号
出版者	Okayama University Medical School
開始ページ	545
終了ページ	552
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37899266
Web of Science KeyUT	001094245100001

Neurological Analysis Based on the Terminal End of the Spinal Cord and the Narrowest Level of Injured Spine in Thoracolumbar Spinal Injuries

JaLCDOI	10.18926/AMO/65972
フルテキストURL	77_5_499.pdf
著者	Hatakeyama, Yuji\| Hongo, Michio\| Kido, Tadato\| Urayama, Masakazu\| Kasukawa, Yuji\| Sasaki, Hiroshi\| Aizawa, Toshiaki\| Kudo, Daisuke\| Kimura, Ryota\| Ono, Yuichi\| Kasama, Fumihito\| Miyakoshi, Naohisa\|
抄録	This study aimed to clarify neurological differences among the epiconus, conus medullaris, and cauda equina syndromes. Eighty-seven patients who underwent surgery for acute thoracolumbar spinal injuries were assessed. We defined the epiconus as the region from the terminal end of the spinal cord to the proximal 1.0 to 2.25 vertebral bodies, the conus medullaris as the region proximal to < 1.0 vertebral bodies, and the cauda equina as the distal part of the nerve roots originating from the spinal cord. On the basis of the distance from the terminal end of the spinal cord to the narrowest level of the spinal canal, the narrowest levels were ordered as follows: the epiconus followed by the conus medullaris and cauda equina. The narrowest levels were the epiconus in 22 patients, conus medullaris in 37 patients, and cauda equina in 25 patients. On admission, significantly more patients had a narrowed epiconus of Frankel grades A-C than a narrowed cauda equina. At the final follow-up, there were no significant differences in neurological recovery among those with epiconus, conus medullaris, or cauda equina syndrome. Anatomically classifying the narrowest lesion is useful for clarifying the differences and similarities among these three syndromes.
キーワード	thoracolumbar spinal injury terminal end of spinal cord conus medullaris epiconus syndrome cauda equina syndrome
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-10
巻	77巻
号	5号
出版者	Okayama University Medical School
開始ページ	499
終了ページ	509
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37899261
Web of Science KeyUT	001108661600007

Childcare and Child Development in Japan

JaLCDOI	10.18926/AMO/65970
フルテキストURL	77_5_479.pdf
著者	Murata, Akiko\| Matsumoto, Naomi\| Miyaji, Chikara\| Takao, Soshi\| Yorifuji, Takashi\|
抄録	For decades, the notion has persisted in developed countries that exclusive care by the mothers is best for the development of children up to 3 years of age. To examine the veracity of this “myth of the first three years” in Japan, we examined the effects of childcare facility use for children younger than 3 years on their development using the cohorts of the Longitudinal Survey of Newborns in the 21st Century conducted in Japan. Of the 47,015 respondents to the survey, we studied the children of 5,508 mothers with university/professional education to evaluate the relationships between primary early (< 2.5 years) childcare providers during weekday daytime hours and specific development indices for the ages of 2.5, 5.5, and 8 years. At the age of 2.5 and 5.5 years, children attending childcare facilities were judged as having more advanced developmental behaviors by their parents, such as being able to compose a two-word sentence (adjusted odds ratio [aOR]: 0.22) or to express emotions (aOR: 0.81), compared with those cared for by mothers. However, at the age of 8 years, children who attended childcare facilities as infants < 2.5 years showed more aggressive behavior in interrupting people (aOR: 1.20) and causing disturbances in public (aOR: 1.26) than those cared for by mothers (after adjustment for numerous child and parental factors). Although these results are generally consistent with previous studies, issues potentially involved with problem behavior such as quality of childcare require further investigation, as does the case of children of mothers with more modest educational attainment.
キーワード	“myth of the first three years” childcare child development problem behavior educational attainment
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-10
巻	77巻
号	5号
出版者	Okayama University Medical School
開始ページ	479
終了ページ	490
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37899259
Web of Science KeyUT	001108661600005

An Assessment Rubric for a Resident Training Program in Surgery: A Single-Institution Experience

JaLCDOI	10.18926/AMO/65967
フルテキストURL	77_5_451.pdf
著者	Okita, Atsushi\| Tsukuda, Kazunori\| Ino, Hideo\| Mitsui, Ema\| Ikeya, Nanami\| Yamamoto, Sumiharu\| Yokoyama, Nobuji\| Bulin, Aubra\|
抄録	Using a Collaborative Action Research model, our research team established a one-month clinical resident training program for first- and second-year clinical residents. We created and implemented an assessment rubric to assess the residents’ progress toward independent practice in surgery, and thereby, to evaluate the program itself. The program included training in three areas: basic techniques and procedures in the operating room, surgical ward management, and academic activities. The rubric measured the residents’ performance according to three achievement levels: Level 1 (demonstration), Level 2 (active help) and Level 3 (passive help). The program and rubric implementation began in June 2019 and continued until March 2020, when the program outcomes and shortcomings were analyzed. Among nineteen clinical residents, a total of nine clinical residents participated in the study. Most participants reached achievement Level 3 for their performance of basic techniques in the operating room. Finally, we discussed ideas for improvement and drafted plans for an improved rubric to complete the action research cycle. Our research team found the rubric to be a useful tool in evaluating the status of the new clinical resident training program.
キーワード	resident program rubric assessment general surgery action research
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-10
巻	77巻
号	5号
出版者	Okayama University Medical School
開始ページ	451
終了ページ	460
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37899256
Web of Science KeyUT	001108661600002

Prognostic Impact of Tumor-Infiltrating Lymphocytes, Tertiary Lymphoid Structures, and Neutrophil-to-Lymphocyte Ratio in Pulmonary Metastases from Uterine Leiomyosarcoma

フルテキストURL	fulltext20231012-01.pdf
著者	Matsuda, Naoki\| Yamamoto, Hiromasa\| Habu, Tomohiro\| Iwata, Kazuma\| Matsubara, Kei\| Tanaka, Shin\| Hashimoto, Kohei\| Shien, Kazuhiko\| Suzawa, Ken\| Miyoshi, Kentaroh\| Toji, Tomohiro\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Takahashi, Katsuhito\| Toyooka, Shinichi\|
備考	The version of record of this article, first published in Annals of Surgical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1245/s10434-023-14176-x\|
発行日	2023-09-01
出版物タイトル	Annals of Surgical Oncology
巻	30巻
号	13号
出版者	Springer Science and Business Media LLC
開始ページ	8727
終了ページ	8734
ISSN	1068-9265
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37658268
DOI	10.1245/s10434-023-14176-x
Web of Science KeyUT	001060201900008
関連URL	isVersionOf https://doi.org/10.1245/s10434-023-14176-x

The Relationship between the Evaluation of Public Transport Services and Travel-Based CO2 Emissions from Private Transport Modes in Regional and Metropolitan Areas in Japan

フルテキストURL	fulltext.pdf
著者	Pradhan, Shreyas\| Ujihara, Takehito\| Hashimoto, Seiji\|
キーワード	CO2 emissions public transport evaluation 'hard' and 'soft' attributes usage frequency private transport modes
発行日	2023-09-05
出版物タイトル	Sustainability
巻	15巻
号	18号
出版者	MDPI
開始ページ	13296
ISSN	2071-1050
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 by the authors.
論文のバージョン	publisher
DOI	10.3390/su151813296
Web of Science KeyUT	001074056100001
関連URL	isVersionOf https://doi.org/10.3390/su151813296

A Case of Acute Zonal Occult Outer Retinopathy in which Oct en Face Imaging Was Useful for Diagnosis and Follow-up

JaLCDOI	10.18926/AMO/65756
フルテキストURL	77_4_433.pdf
著者	Ono, Ryuki\| Shiode, Yusuke\| Kimura, Shuhei\| Hosokawa, Mio\| Matoba, Ryo\| Kanzaki, Yuki\| Kindo, Hiroya\| Morita, Tetsuro\| Morizane, Yuki\|
抄録	A 23-year-old woman presented with a 1-month history of visual abnormalities in her right eye. A visual field test revealed temporal abnormalities in the right eye. Optical coherence tomography revealed an indistinct ellipsoid zone (EZ) on the B-scan image and hyporeflective areas in the EZ layer on the en face image in the right eye. We diagnosed the patient with acute zonal occult outer retinopathy. Visual field tests and B-scan images improved to almost normal at 6 months, but hyporeflective areas remained on the en face images. Thus, en face images may be more sensitive at detecting abnormalities in the outer retina than other modalities.
キーワード	acute zonal occult outer retinopathy optical coherence tomography en face image ellipsoid zone
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	433
終了ページ	437
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635145
Web of Science KeyUT	001088434900001

Association of Tumor Necrosis Factor-Alpha with Psychopathology in Patients with Schizophrenia

JaLCDOI	10.18926/AMO/65750
フルテキストURL	77_4_395.pdf
著者	Pavlovic, Marko\| Babic, Dragan\| Rastovic, Pejana\| Arapovic, Jurica\| Martinac, Marko\| Jakovac, Sanja\| Barbaric, Romana\|
抄録	We investigated the relationship between serum tumor necrosis factor-alpha (TNF-α) levels and psychopathological symptoms, clinical and socio-demographic characteristics and antipsychotic therapy in individuals with schizophrenia. TNF-α levels were measured in 90 patients with schizophrenia and 90 healthy controls matched by age, gender, smoking status, and body mass index. The Positive and Negative Syndrome Scale (PANSS) was used to assess the severity of psychopathology in patients. No significant differences in TNF-α levels were detected between the patients and controls (p=0.736). TNF-α levels were not correlated with total, positive, negative, general, or composite PANSS scores (all p>0.05). A significant negative correlation was observed between TNF-α levels and the PANSS cognitive factor (ρ=−0.222, p=0.035). A hierarchical regression analysis identified the cognitive factor as a significant predictor of the TNF-α level (beta=−0.258, t=−2.257, p=0.027). There were no significant differences in TNF-α levels among patients treated with different types of antipsychotics (p=0.596). TNF-α levels correlated positively with the age of onset (ρ=0.233, p=0.027) and negatively with illness duration (ρ=−0.247, p=0.019) and antipsychotic treatment duration (ρ=−0.256, p=0.015). These results indicate that TNF-α may be involved in cognitive impairment in schizophrenia, and would be a potential clinical-state marker in schizophrenia.
キーワード	tumor necrosis factor-alpha schizophrenia psychopathology immune system
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	395
終了ページ	405
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635140
Web of Science KeyUT	001163659800010