検索結果 - 岡山大学学術成果リポジトリ

Mammalian type opsin 5 preferentially activates G14 in Gq-type G proteins triggering intracellular calcium response

フルテキストURL	fulltext.pdf
著者	Sato, Keita\| Yamashita, Takahiro\| Ohuchi, Hideyo\|
キーワード	G protein G protein−coupled receptor (GPCR) photoreceptor rhodopsin calcium intracellular release protein−protein interaction signal transduction nonvisual photoreception
発行日	2023-08
出版物タイトル	Journal of Biological Chemistry
巻	299巻
号	8号
出版者	Elsevier
開始ページ	105020
ISSN	1083-351X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Authors.
論文のバージョン	publisher
PubMed ID	37423300
DOI	10.1016/j.jbc.2023.105020
Web of Science KeyUT	001166411500001
関連URL	isVersionOf https://doi.org/10.1016/j.jbc.2023.105020

Structural insights into the action mechanisms of artificial electron acceptors in photosystem II

フルテキストURL	fulltext.pdf
著者	Kamada, Shinji\| Nakajima, Yoshiki\| Shen, Jian-Ren\|
キーワード	Photosystem II photosynthesis electron transfer structural biology crystal structure electron acceptor
発行日	2023-07
出版物タイトル	Journal of Biological Chemistry
巻	299巻
号	7号
出版者	Elsevier
開始ページ	104839
ISSN	1083-351X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Authors.
論文のバージョン	publisher
PubMed ID	37209822
DOI	10.1016/j.jbc.2023.104839
Web of Science KeyUT	001166336800001
関連URL	isVersionOf https://doi.org/10.1016/j.jbc.2023.104839

裏表紙・英文目次

フルテキストURL	olj_73_3_contents_eng.pdf
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

奥付

フルテキストURL	olj_73_3_colophon.pdf
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

本号執筆者紹介

フルテキストURL	olj_73_3_authors.pdf
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
開始ページ	293
終了ページ	293
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

Making Political Justice More Open to Religions: Reconstructing Political Liberalism

フルテキストURL	olj_73_3_155_200.pdf
著者	大森秀臣\|
抄録	Today, religious groups have increasingly represented themselves in various public scenes, making it difficult to address the issues under the existing legal framework; the separation of church and state and freedom of religion. Though political liberals, such as Rawls, have proposed a conception of political justice that attempts to be tolerant of religions, it is limited by their view of the public/private distinction as given and their representative viewpoint of public authority. To make political justice more open to religions, a paradigm shift to the religious viewpoint should be necessary. Political liberalism then is reconstructed so that it opens an interactive process between justice and religions. A theorist, adopting a distanced internal perspective of religions, can help with this task by providing a list of doctrinal reasons that religious believers can voluntarily endorse and appeal to when they are involved in consensus and deliberation.
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
開始ページ	200
終了ページ	155
ISSN	0386-3050
言語	英語
論文のバージョン	publisher

戦後特許法執行体制の形成過程

タイトル（別表記）	Formation Process of the Operating System on Patent Law in Postwar Japan
フルテキストURL	olj_73_3_201_260.pdf
著者	大泉陽輔\|
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
開始ページ	260
終了ページ	201
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

対話型調停での非定型的な紛争の語り

タイトル（別表記）	Telling of the Trouble in Mediation
フルテキストURL	olj_73_3_262_292.pdf
著者	李英\|
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
開始ページ	292
終了ページ	262
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

表紙・目次

フルテキストURL	olj_73_3_contents.pdf
出版物タイトル	岡山大學法學會雜誌
発行日	2024-02-26
巻	73巻
号	3号
ISSN	0386-3050
言語	日本語
論文のバージョン	publisher

Clinical characteristics of patients treated with immune checkpoint inhibitors in EGFR-mutant non-small cell lung cancer: CS-Lung-003 prospective observational registry study

フルテキストURL	fulltext20240226-04.pdf
著者	Kuribayashi, Tadahiro\| Ohashi, Kadoaki\| Nishii, Kazuya\| Ninomiya, Kiichiro\| Tsubata, Yukari\| Ishikawa, Nobuhisa\| Kodani, Masahiro\| Kanaji, Nobuhiro\| Yamasaki, Masahiro\| Fujitaka, Kazunori\| Kuyama, Shoichi\| Takigawa, Nagio\| Fujimoto, Nobukazu\| Kubota, Tetsuya\| Inoue, Masaaki\| Fujiwara, Keiichi\| Harita, Shingo\| Takata, Ichiro\| Takada, Kenji\| Okawa, Sachi\| Kiura, Katsuyuki\| Hotta, Katsuyuki\|
キーワード	EGFR EGFR-TKI Lung cancer Immune checkpoint inhibitors Performance status
備考	The version of record of this article, first published in Journal of Cancer Research and Clinical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00432-024-05618-4\|
発行日	2024-02-12
出版物タイトル	Journal of Cancer Research and Clinical Oncology
巻	150巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	89
ISSN	1432-1335
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	38347279
DOI	10.1007/s00432-024-05618-4
Web of Science KeyUT	001160773600002
関連URL	isVersionOf https://doi.org/10.1007/s00432-024-05618-4

Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

フルテキストURL	fulltext20240226-03.pdf
著者	Zhou, Wenhao\| Kawashima, Shusuke\| Ishino, Takamasa\| Kawase, Katsushige\| Ueda, Youki\| Yamashita, Kazuo\| Watanabe, Tomofumi\| Kawazu, Masahito\| Dansako, Hiromichi\| Suzuki, Yutaka\| Nishikawa, Hiroyoshi\| Inozume, Takashi\| Nagasaki, Joji\| Togashi, Yosuke\|
キーワード	cancer immunology follicular helper T cell cytotoxic CD4+ T cell CXCL13 T cell exhaustion stem-like progenitor exhaustion terminally differentiated exhaustion PD-1 LAG-3 TCF1
備考	Immune checkpoint inhibitors exert clinical efficacy against various types of cancer through reinvigoration of exhausted CD8+ T cells that attack cancer cells directly in the tumor microenvironment (TME). Using single-cell sequencing and mouse models, we show that CXCL13, highly expressed in tumor-infiltrating exhausted CD8+ T cells, induces CD4+ follicular helper T (TFH) cell infiltration, contributing to anti-tumor immunity. Furthermore, a part of the TFH cells in the TME exhibits cytotoxicity and directly attacks major histocompatibility complex-II-expressing tumors. TFH-like cytotoxic CD4+ T cells have high LAG-3/BLIMP1 and low TCF1 expression without self-renewal ability, whereas non-cytotoxic TFH cells express low LAG-3/BLIMP1 and high TCF1 with self-renewal ability, closely resembling the relationship between terminally differentiated and stem-like progenitor exhaustion in CD8+ T cells, respectively. Our findings provide deep insights into TFH-like CD4+ T cell exhaustion with helper progenitor and cytotoxic differentiated functions, mediating anti-tumor immunity orchestrally with CD8+ T cells.\|
発行日	2024-02-27
出版物タイトル	Cell Reports
巻	43巻
号	2号
出版者	Elsevier BV
開始ページ	113797
ISSN	2211-1247
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Author(s).
論文のバージョン	publisher
PubMed ID	38363680
DOI	10.1016/j.celrep.2024.113797
Web of Science KeyUT	001185865700001
関連URL	isVersionOf https://doi.org/10.1016/j.celrep.2024.113797

Preliminary Study of Dental Caries Detection by Deep Neural Network Applying Domain-Specific Transfer Learning

フルテキストURL	fulltext20240226-01.pdf
著者	Kawazu, Toshiyuki\| Takeshita, Yohei\| Fujikura, Mamiko\| Okada, Shunsuke\| Hisatomi, Miki\| Asaumi, Junichi\|
キーワード	Deep neural networks Caries detection Domain-Specific transfer learning Panoramic tomography
備考	The version of record of this article, first published in Journal of Medical and Biological Engineering, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40846-024-00848-w\|
発行日	2024-02-13
出版物タイトル	Journal of Medical and Biological Engineering
巻	44巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	43
終了ページ	48
ISSN	1609-0985
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
DOI	10.1007/s40846-024-00848-w
Web of Science KeyUT	001160649900001
関連URL	isVersionOf https://doi.org/10.1007/s40846-024-00848-w

The first presentation of a case of nail-patella syndrome newly diagnosed at the onset of rheumatoid arthritis: a case report

フルテキストURL	fulltext.pdf
著者	Matsumoto, Kazuya\| Matsumoto, Yoshinori\| Nawachi, Shoichi\| Asano, Yosuke\| Katayama, Yu\| Miyawaki, Yoshia\| Katsuyama, Takayuki\| Katsuyama, Eri\| Nasu, Yoshihisa\| Sada, Ken-Ei\| Wada, Jun\|
キーワード	Nail-patella syndrome Rheumatoid arthritis Joint dislocation Iliac horn Case report
備考	The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-024-07242-2\|
発行日	2024-02-14
出版物タイトル	BMC Musculoskeletal Disorders
巻	25巻
号	1号
出版者	BMC
開始ページ	139
ISSN	1471-2474
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024.
論文のバージョン	publisher
PubMed ID	38355529
DOI	10.1186/s12891-024-07242-2
Web of Science KeyUT	001162669400002
関連URL	isVersionOf https://doi.org/10.1186/s12891-024-07242-2

Aromatic oil from lavender as an atopic dermatitis suppressant

フルテキストURL	fulltext.pdf
著者	Sato, Haruna\| Kato, Kosuke\| Koreishi, Mayuko\| Nakamura, Yoshimasa\| Tsujino, Yoshio\| Satoh, Ayano\|
発行日	2024-01-05
出版物タイトル	PLoS ONE
巻	19巻
号	1号
出版者	Public Library of Science
開始ページ	e0296408
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Sato et al.
論文のバージョン	publisher
PubMed ID	38181031
DOI	10.1371/journal.pone.0296408
Web of Science KeyUT	001153716700065
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0296408

Inhibitory Effect of a Tankyrase Inhibitor on Mechanical Stress-Induced Protease Expression in Human Articular Chondrocytes

フルテキストURL	fulltext.pdf
著者	Hotta, Yoshifumi\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Naniwa, Shuichi\| Shimizu, Noriyuki\| Ichikawa, Chinatsu\| Lin, Deting\| Fujiwara, Tomohiro\| Ozaki, Toshifumi\|
キーワード	osteoarthritis chondrocyte mechanical stress tankyrases XAV939 SOX9 ADAMTS-5 MMP-13 IL-1β NF-κB β-catenin
発行日	2024-01-24
出版物タイトル	International Journal of Molecular Sciences
巻	25巻
号	3号
出版者	MDPI
開始ページ	1443
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
PubMed ID	38338721
DOI	10.3390/ijms25031443
Web of Science KeyUT	001161430700001
関連URL	isVersionOf https://doi.org/10.3390/ijms25031443

Evaluation of transducer for cryogenic actuators by equivalent circuit model

フルテキストURL	fulltext20240222-01.pdf
著者	Kubo, Kazuki\| Yagi, Kairi\| Kanda, Takefumi\| Yasuda, Koa\| Yamaguchi, Daisuke\| Wakimoto, Shuichi\|
キーワード	cryogenic ultrasonic piezoelectric transducer
備考	This is the Accepted Manuscript version of an article accepted for publication in Japanese Journal of Applied Physics. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.35848/1347-4065/ad1e9b.\| This fulltext file will be available in Feb. 2025.\|
発行日	2024-02-07
出版物タイトル	Japanese Journal of Applied Physics
巻	63巻
号	3号
出版者	IOP Publishing
開始ページ	03SP03
ISSN	0021-4922
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Japan Society of Applied Physics
論文のバージョン	author
DOI	10.35848/1347-4065/ad1e9b
Web of Science KeyUT	001157397300001
関連URL	isVersionOf https://doi.org/10.35848/1347-4065/ad1e9b

Ectopic Breast Cancer Arising within an Axillary Lymph Node

JaLCDOI	10.18926/AMO/66676
フルテキストURL	78_1_089.pdf
著者	Toshima, Kei\| Shien, Tadahiko\| Nishimura, Midori Filiz\| Suzuki, Yoko\| Nakamoto, Shogo\| Uno, Maya\| Yoshioka, Ryo\| Tsukioki, Takahiro\| Takahashi, Yuko\| Iwamoto, Takayuki\| Iwatani, Tsuguo\| Yanai, Hiroyuki\|
抄録	We report our experience with the diagnosis and treatment of an ectopic breast cancer arising within an axillary lymph node. The patient was a 65-year-old woman diagnosed breast cancer and axillary lymph node metastasis. We performed a partial mastectomy and axillary lymph node dissection. Postoperative pathology revealed no malignant lesions in the breast; however, a nodule in one of axillary lymph nodes had mixed benign and malignant components, leading to a diagnosis of invasive ductal carcinoma derived from ectopic mammary tissue. This case represents a very rare form of breast cancer, and the malignancy was difficult to distinguish from metastasis.
キーワード	breast cancer ectopic breast cancer axillary lymph node
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2024-02
巻	78巻
号	1号
出版者	Okayama University Medical School
開始ページ	89
終了ページ	93
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38419320
Web of Science KeyUT	001204421300001

A Case of Idiopathic Peptic Ulcer Disease Treated Effectively with Trimebutine Maleat

JaLCDOI	10.18926/AMO/66675
フルテキストURL	78_1_085.pdf
著者	Miyake, Keisuke\| Tanikawa, Tomohiro\| Haruma, Ken\| Kawada, Mayuko\| Ishii, Katsunori\| Urata, Noriyo\| Nishino, Ken\| Suehiro, Mitsuhiko\| Kawanaka, Miwa\| Manabe, Noriaki\| Kawamoto, Hirofumi\|
抄録	A 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential efficacy of TM in treating IPUD and the importance of considering hypercontractility as the underlying cause in cases of IPUD.
キーワード	gastric ulcer idiopathic peptic ulcerative disease trimebutine maleate
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2024-02
巻	78巻
号	1号
出版者	Okayama University Medical School
開始ページ	85
終了ページ	88
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38419319
Web of Science KeyUT	001204421300002

Utility of Combined Use of Transabdominal Ultrasonography and Fecal Immunochemical Test Examinations in Ulcerative Colitis

JaLCDOI	10.18926/AMO/66674
フルテキストURL	78_1_079.pdf
著者	Takahara, Masahiro\| Hiraoka, Sakiko\| Ohmori, Masayasu\| Takeuchi, Keiko\| Takei, Kensuke\| Aoyama, Yuki\| Yasutomi, Eriko\| Igawa, Shoko\| Inokuchi, Toshihiro\| Toyosawa, Junki\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Harada, Keita\| Onishi, Hideki\| Okada, Hiroyuki\|
抄録	This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies.
キーワード	transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore
Amo Type	Short Communication
出版物タイトル	Acta Medica Okayama
発行日	2024-02
巻	78巻
号	1号
出版者	Okayama University Medical School
開始ページ	79
終了ページ	83
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38419318
Web of Science KeyUT	001203658200004

High Fracture Rate of AVANTA Silicone Implant Following Arthroplasty of the Thumb MCP Joint of Rheumatoid Arthritis Patients with Boutonniere Deformities

JaLCDOI	10.18926/AMO/66673
フルテキストURL	78_1_071.pdf
著者	Kaneda, Daisuke\| Nishida, Keiichiro\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Harada, Ryozo\| Hotta, Yoshifumi\| Naniwa, Shuichi\| Ozaki, Toshifumi\|
抄録	We retrospectively investigated the mid-term outcomes of arthroplasty using the AVANTA silicone implant for thumb metacarpophalangeal (MCP) joints with boutonniere deformity in patients with rheumatoid arthritis (RA). This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoperative flexion range of the implant-fracture group were significantly greater than those in the no-implant-fracture group (p=0.039, 0.034, respectively). These results suggest the importance of patient education and careful rehabilitation to prevent excessive flexion. Overall, the AVANTA silicone implant showed a relatively high rate of implant fracture at our institute.
キーワード	AVANTA silicone implant boutonniere deformity implant fracture thumb metacarpophalangeal joint arthroplasty rheumatoid arthritis
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-02
巻	78巻
号	1号
出版者	Okayama University Medical School
開始ページ	71
終了ページ	78
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38419317
Web of Science KeyUT	001203658200011