| ID | 16275 |
| Eprint ID | 16275
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| フルテキストURL | |
| タイトル（別表記） | Function of peripheral blood lymphocytes in patients with systemic lupus erythematosus. Part 1. Characteristics of spontaneously proliferating cells
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| 著者 |
盛政 公明
岡山大学医学部第三内科学教室
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| 抄録 | Increased 3H-Thymidine(3H-TdR) uptake was noticed when peripheral blood mononuclear cells (MNC) from systemic lupus erythematosus(SLE) patients were cultured without any mitogenic stimulation. The peak of 3H-TdR uptake was found immediately after transfering the cells to in vitro culture. DNA synthesizing cells were observed directly by means of autoradiography by pulsing with 3H-TdR for 4 hours. Therefore, it was presumed that there were some MNC in the peripheral blood from SLE patients which were already triggered to proliferate in vivo. These spontaneously proliferating MNC were found to fractionate into a nonadherent, non-E-rosette forming and surface immunoglobulin negative cell population, the so called null cell population. These results suggest that there were activated MNC in the peripheral blood from patients with SLE which fractionated into a null cell population.
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| キーワード | systemic lupus erythematosus
peripheral blood lymphocytes
spontaneously proliferating cells
null cell fraction
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| 発行日 | 1983-04-30
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| 出版物タイトル |
岡山医学会雑誌
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| 出版物タイトル（別表記） | Journal of Okayama Medical Association
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| 巻 | 95巻
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| 号 | 3-4号
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| 出版者 | 岡山医学会
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| 出版者（別表記） | Okayama Medical Association
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| 開始ページ | 233
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| 終了ページ | 242
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| ISSN | 0030-1558
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| NCID | AN00032489
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| 資料タイプ |
学術雑誌論文
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| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/95/3-4/95_3-4_233/_article/-char/ja/
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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| 言語 |
日本語
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| 著作権者 | 岡山医学会
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| 論文のバージョン | publisher
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| 査読 |
有り
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| Eprints Journal Name | joma
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