検索結果 47530 件
| フルテキストURL | 009.pdf |
|---|---|
| 著者 | 岡山大学資源生物科学研究所| |
| 出版物タイトル | 岡山大学資源生物科学研究所報告 |
| 発行日 | 2001 |
| 巻 | 9巻 |
| ISSN | 0916-930X |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| フルテキストURL | 008.pdf |
|---|---|
| 著者 | 岡山大学資源生物科学研究所| |
| 出版物タイトル | 岡山大学資源生物科学研究所報告 |
| 発行日 | 2000 |
| 巻 | 8巻 |
| ISSN | 0916-930X |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| フルテキストURL | 007.pdf |
|---|---|
| 著者 | 岡山大学資源生物科学研究所| |
| 出版物タイトル | 岡山大学資源生物科学研究所報告 |
| 発行日 | 1999 |
| 巻 | 7巻 |
| ISSN | 0916-930X |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/AMO/52660 |
|---|---|
| フルテキストURL | 68_3_183.pdf |
| 著者 | Hasegawa, Kenjiro| Namba, Yuzaburo| Kimata, Yoshihiro| |
| 抄録 | Since 2001, we have been performing phalloplasty with a radial forearm free flap as the flap of first choice in female-to-male transsexuals (FTMTS). In the present case, a 22-year-old FTMTS with a negative Allen test, we achieved good results by performing phalloplasty with an innervated island pedicled anterolateral thigh flap using the “tube within a tube” technique, in which the penis and urethra are constructed with a single flap. As compared to a forearm flap, use of an innervated islandpedicled flap may have the following advantages in phalloplasty: 1) no need for a microsurgical technique; 2) no scars at noticeable sites; 3) small functional loss in the flap donor area; 4) no sacrifice of major blood vessels. Thus, this technique seems to be a useful clinical alternative for phallic reconstruction. |
| キーワード | gender identity disorder sex reassignment surgery (SRS) phalloplasty |
| Amo Type | Corrected and Republished Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 183 |
| 終了ページ | 190 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24945633 |
| Web of Science KeyUT | 000337655600009 |
| 関連URL | http://doi.org/10.18926/AMO/51869 |
| JaLCDOI | 10.18926/AMO/52659 |
|---|---|
| フルテキストURL | 68_3_177.pdf |
| 著者 | Mizuno, Shoma| Ota, Seisuke| Tanaka, Takehiro| Shiomi, Kohei| Matsumura, Tadashi| Kishimoto, Nobuyasu| |
| 抄録 | Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for those previously exposed to asbestos. He had been smoking since the age of 32. In September 2010, chest CT during this regular checkup revealed a polypoid lesion in his trachea and pleural plaques, which were suspected to be caused by asbestos. Bronchoscopy performed in October revealed a polypoid lesion with granules and nodules in the trachea. A diagnosis of non-Hodgkin lymphoma (NHL) and extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) was confirmed by histological analysis of the biopsy specimens. To our knowledge, this is the first case of primary tracheal lymphoma associated with a history of asbestos exposure. Several reports have documented no correlation between asbestos and malignant lymphoma. In addition, the correlation between smoking and NHL is weak. Although we cannot exclude the possibility of a simple coincidence of asbestos, smoking, and tracheal lymphoma, this case suggests that asbestos and smoking might have multiplicative effects in the development or progression of tracheal lymphoma. |
| キーワード | bronchus-associated lymphoid tissue tracheal lymphoma regular checkup asbestos smoking |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 177 |
| 終了ページ | 181 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942797 |
| Web of Science KeyUT | 000337655600008 |
| JaLCDOI | 10.18926/AMO/52658 |
|---|---|
| フルテキストURL | 68_3_171.pdf |
| 著者 | Hagiya, Hideharu| Matsumoto, Mitsuaki| Yamasawa, Takahiko| Haruki, Yuto| Otsuka, Fumio| |
| 抄録 | A 79-year-old man who had undergone a right femoropopliteal (FP) bypass operation 6 weeks previously was diagnosed with vascular graft infection caused by Staphylococcus lugdunensis. Another FP bypass operation was performed, with long-term administration of antibiotics, and the patient eventually recovered well without any recurrences for over 2 years. Although S. lugdunens is classified as coagulase-negative Staphylococcus, its pathogenicity has been reported to be equal to that of S. aureus. Based on the literature review, the organism characteristically colonizes the inguinal area of human skin;thus, operations such as FP bypass grafting may place patients at a relatively high risk for infection by S. lugdunensis, a potentially high-pathogenicity organism. |
| キーワード | coagulase-negative Staphylococcus (CNS) femoropopliteal (FP) bypass Staphylococcus lugdunensis vacuum-assisted closure (VAC) therapy vascular graft infection (VGI) |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 171 |
| 終了ページ | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942796 |
| Web of Science KeyUT | 000337655600007 |
| JaLCDOI | 10.18926/AMO/52657 |
|---|---|
| フルテキストURL | 68_3_163.pdf |
| 著者 | Tate, Genshu| Kishimoto, Koji| Mitsuya, Toshiyuki| |
| 抄録 | The aim of the present study is to address whether the molecular pathogenesis is identical among multiple basal cell carcinomas (BCCs) present in the same nevoid basal cell carcinoma syndrome (NBCCS) patient. Patient 1 is a 61-year-old (yo) Japanese female whose clinical characteristics and findings of a genetic analysis of PTCH1 have been previously described. Patient 2 is patient 1ʼs 64-yo sister who also suffered from NBCCS with a single base deletion at nucleotide 2613 in exon 16 (c.2613delC) in one PTCH1 allele. Thirteen and 3 independent specimens of BCC were applied for a molecular analysis of loss of heterozygosity (LOH) in PTCH1 in patients 1 and 2, respectively. Of particular note is that all BCC specimens examined showed a loss of the wild-type allele of exon 16 in PTCH1, thus indicating that LOH results in the biallelic disruption of PTCH1 in multiple BCCs that develop in an age- and location-independent manner in the same patient. These results indicate that the germline single base deletion of PTCH1 (c.2613 delC) is a first hit and the LOH of the wild-type allele is a second hit, implying that all 16 BCCs detected in these NBCCS sisters fit the standard two-hit model. |
| キーワード | biallelic disruption hedgehog nevoid basal cell carcinoma syndrome Patched 1 two-hit model |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 163 |
| 終了ページ | 170 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942795 |
| Web of Science KeyUT | 000337655600006 |
| JaLCDOI | 10.18926/AMO/52656 |
|---|---|
| フルテキストURL | 68_3_157.pdf |
| 著者 | Oozawa, Susumu| Sano, Shunji| Nishibori, Masahiro| |
| 抄録 | Atherosclerosis is often associated with chronic vascular inflammation. High-mobility group box 1 protein (HMGB1) plays various roles, not only as a transcriptional regulatory factor in the nucleus, but also as an inflammatory mediator. A previous study suggested that fibrinogen is an important factor associated with atherosclerosis progression. The present study was performed to examine the levels of plasma HMGB1 protein in atherosclerosis patients. We studied 24 patients with peripheral artery disease (PAD) with atherosclerosis, and 10 healthy controls. We found that the concentrations of HMGB1 were increased in the plasma of the patients with atherosclerosis, and there were significant correlations between the plasma HMGB1 and fibrinogen levels. Plasma HMGB1 may play a key role in the pathogenesis of clinical and experimental atherosclerosis. |
| キーワード | HMGB1 fibrinogen atherosclerosis peripheral artery disease |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 157 |
| 終了ページ | 162 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942794 |
| Web of Science KeyUT | 000337655600005 |
| 関連URL | http://doi.org/10.18926/AMO/52792 |
| JaLCDOI | 10.18926/AMO/52655 |
|---|---|
| フルテキストURL | 68_3_151.pdf |
| 著者 | Akavipat, Phuping| Hungsawanich, Nate| Jansin, Rungruedee| |
| 抄録 | In neurosurgery in particular, the recommended placement of electrodes for monitoring depth of anesthesia during surgery sometimes conflicts with the surgical site or patient positioning. Therefore, we proposed this study to evaluate the agreement and correlation of bispectral index values recorded from the usual frontal area and the alternate, post-auricular areas in neurosurgery patients. Thirty-four patients scheduled for neurosurgery under general anesthesia were included. Bispectral index (BIS) sensors were placed at both the frontal and post-auricular areas. The anesthesia given was clinically adjusted according to the frontal (standard) BIS reading. The BIS values and impedance were recorded;Pearsonʼs correlation and Bland-Altman plots were analyzed. The bias ± 2SD for the electrode placement before, during, and post-anesthesia were 0±23.32, 1.5±10.69, and 2.1±13.52, while the limits of agreement were －23.3 to 23.3, －12.2 to 9.2, and －17.7 to 13.5, respectively. The correlation coefficient between frontal- and post-auricular-area electrodes was 0.74 with a p-value ＜0.001.The post-auricular placement of a BIS electrode is a practical alternative to frontal lobe placement. Nevertheless, proper electrode location is important to minimize error. |
| キーワード | Bland and Altman analysis electroencephalogram instrumentation equipment |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 151 |
| 終了ページ | 155 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942793 |
| Web of Science KeyUT | 000337655600004 |
| JaLCDOI | 10.18926/AMO/52654 |
|---|---|
| フルテキストURL | 68_3_143.pdf |
| 著者 | Yamaguchi, Junichi| Imatoh, Takuya| Une, Hiroshi| |
| 抄録 | The purpose of this study was to clarify, through a prospective study, the relationship between leptin and adiponectin levels, and subsequent weight change. The study subjects were 2,485 male office workers aged 35-64 employed by a company in Fukuoka Prefecture, Japan. Of these men, 1,936 (77.9%) received health check-ups both in 2005-2007 and 3 years later, in 2008-2010. Of the subjects who received both health check-ups, 352 were excluded duo to cancer, cardiac infarction, stroke or diabetes mellitus, leaving a total of 1,584. We divided them into tertiles according to baseline leptin and adiponectin levels, and compared the subsequent change in body mass index (BMI) over 3 years. The subjects with the lowest leptin levels showed a significantly greater increase in BMI (difference in change in BMI＝0.178kg/m2, 95% CI:0.025-0.331kg/m2) over 3 years when those with the highest leptin levels were regarded as the reference even after adjusting for age, baseline BMI, smoking status, drinking status and exercise. The subjects with the highest adiponectin levels showed a greater increase in BMI (difference in change in BMI＝0.099kg/m2, 95% CI:－0.034-0.231kg/m2) over 3 years when those with the lowest adiponectin levels were regarded as the reference, but this association was not statistically significant after adjusting for age, baseline BMI, smoking status, drinking status and exercise. Our findings suggest that higher leptin levels may suppress weight gain in Japanese male workers. |
| キーワード | leptin adiponectin weight change Japanese male workers prospective study |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 143 |
| 終了ページ | 149 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942792 |
| Web of Science KeyUT | 000337655600003 |
| JaLCDOI | 10.18926/AMO/52653 |
|---|---|
| フルテキストURL | 68_3_137.pdf |
| 著者 | Akamatsu, Megumi| Nakatsuka, Mikiya| |
| 抄録 | Untouched toe is a condition in which a toe does not touch the ground while standing. It is frequently observed in women even under physiological conditions. Deformities or symptoms of the toes are not observed in these women. The clinical significance of untouched toe has not been fully elucidated. Two hundred young healthy women were recruited into the present study after informed consent. We evaluated the prevalence of untouched toe by measuring various indexes of the toe using a foot-sole-measuring equipment. We also conducted a self-administered questionnaire regarding general malaise. Untouched toe was observed in 114 of these 200 women (57.0%). The fifth toe was more frequently affected than the other toes. There were no significant differences in size of foot except the area and proportion touching the ground between women with untouched toe and those without untouched toe. The prevalence of general malaise was significantly higher in women with at least one untouched toe (57.0%) compared with those without untouched toe (43.0%) (p＜0.05). Twelve symptoms―irritability, headache, tired eyes, hazy vision, congested or runny nose, irregular menstruation or menstrual pain, shoulder stiffness, neck stiffness, low back pain, cold hands, swollen feet, and cold feet―were more frequently observed in women with at least one untouched toe compared with those without untouched toes. Untouched toe was associated with various symptoms of general malaise. However, the pathological mechanism by which untouched toe causes these symptoms has not been determined. Further analysis of gait and exercise habits in women with untouched toe is necessary. |
| キーワード | cold feet general malaise shoulder stiffness untouched toe young women |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 137 |
| 終了ページ | 142 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942791 |
| Web of Science KeyUT | 000337655600002 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52635 |
| JaLCDOI | 10.18926/AMO/52652 |
|---|---|
| フルテキストURL | 68_3_129.pdf |
| 著者 | Minoura, Akira| Wang, Da-Hong| Sato, Yoshie| Zou, Yu| Sakano, Noriko| Kubo, Masayuki| Takemoto, Kei| Masatomi, Chie| Ogino, Keiki| |
| 抄録 | We examined the relationships between dietary carbohydrate, protein, fat, and the ratio of n6/n3 fatty acid intakes with the predicted 10-year coronary heart disease (CHD) risk in a general Japanese population. We used the Framingham risk score to determine the 10-year CHD risk of the subjects, who were employees of 6 companies in a single prefecture in Japan. After excluding the subjects who reported any history of angina pectoris, myocardial infarction, diabetes, or cancer, and those with missing data resulting in the inability of estimation of 10-year CHD risk and food intakes, the final data analysis was carried out for 809 subjects. The logistic regression models revealed a significantly increased odds ratio of 10-year CHD risk in the subjects with the highest tertile of carbohydrate intake (% energy) (odds ratio 3.64, 95% CI, 2.07-6.40);after adjustment for other variables, the odds ratio for the 10-year CHD risk was also higher in the subjects with the highest tertile of carbohydrate intake (odds ratio 1.72, 95% CI, 0.70-4.25). We also found that fat intake and the ratio of n6/n3 fatty acids were inversely associated with the predicted 10-year CHD risk (p for trend＜0.01). The present findings added evidence of a positive association of dietary carbohydrate and inverse associations of total fat and n6/n3 fatty acid ratio with the predicted 10-year CHD risk in a general Japanese population. |
| キーワード | fat intake carbohydrate intake ratio of n6/n3 fatty acids 10-year coronary heart disease risk Japanese |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 129 |
| 終了ページ | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942790 |
| Web of Science KeyUT | 000337655600001 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52516 |
| 著者 | 山本 秀夫| |
|---|---|
| 発行日 | 2014-03-25 |
| 出版物タイトル | |
| 資料タイプ | 学位論文 |
| フルテキストURL | O0004421_abstract_review.pdf O0004421_fulltext.pdf |
|---|---|
| 著者 | 南里 敬弘| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4421号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（理学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | O0004420_abstract_review.pdf O0004420_fulltext.pdf |
|---|---|
| 著者 | 吉田 耕平| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4420号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（理学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 英語 |
| フルテキストURL | O0004419_abstract_review.pdf O0004419_fulltext.pdf |
|---|---|
| 著者 | 安東 雅訓| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4419号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（理学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | O0004418_abstract_review.pdf O0004418_fulltext.pdf |
|---|---|
| 著者 | 成瀬 守| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4418号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（薬学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | O0004417_abstract_review.pdf O0004417_fulltext.pdf |
|---|---|
| 著者 | 大西 順子| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4417号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（薬学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | O0004416_abstract_review.pdf O0004416_fulltext.pdf |
|---|---|
| 著者 | 大山 和美| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4416号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（学術） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | K0005010_abstract_review.pdf K0005010_fulltext.pdf |
|---|---|
| 著者 | 豊田 圭子| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5010号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（文学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |