検索結果 582 件
| フルテキストURL | fulltext20230428-01.pdf |
|---|---|
| 著者 | Obata, K.| Yutori, H.| Yoshida, K.| Sakamoto, Y.| Ono, K.| Ibaragi, S.| |
| キーワード | Oral cancer Tumor markers Squamous cell carcinoma Tumor antigens CYFRA cytokeratin fragment Renal function |
| 備考 | © 2022 International Association of Oral and Maxillofacial Surgeons. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.ijom.2022.08.019. | This fulltext file will be available in Apr. 2024.| |
| 発行日 | 2023-04 |
| 出版物タイトル | International Journal of Oral and Maxillofacial Surgery |
| 巻 | 52巻 |
| 号 | 4号 |
| 出版者 | Elsevier BV |
| 開始ページ | 417 |
| 終了ページ | 422 |
| ISSN | 0901-5027 |
| NCID | AA10682150 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 International Association of Oral and Maxillofacial Surgeons. |
| 論文のバージョン | author |
| PubMed ID | 36096859 |
| DOI | 10.1016/j.ijom.2022.08.019 |
| Web of Science KeyUT | 000953117300001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.ijom.2022.08.019 |
| タイトル（別表記） | An in-hospital relapse case of an elderly COVID-19 patient on steroids |
|---|---|
| フルテキストURL | 134_171.pdf |
| 著者 | 藤田 浩二| 大重 和樹| |
| 抄録 | During a pandemic like the novel coronavirus infection 2019 (COVID-19), the availability of inpatient beds is always a major issue. Thus, it is extremely important to release patients from isolation efficiently in order to maintain stable bed operations. However, in clinical practice, patients may develop fever again, before or after the timing specified by the Ministry of Health, Labor and Welfare (MHLW) for lifting isolation, and hence it may be difficult to determine whether the fever is due to a delay in recovery or due to relapse. The diagnosis of relapse is based primarily on the recurrence of symptoms consistent with COVID-19 and a positive PCR result, but few reports have focused on comparing the patterns of variation in two or more blood test findings over the course of the disease. In the present study, we study a case of relapse in an elderly patient on immunosuppressive drugs. Understanding the unique patterns of variability between baseline blood test values and acute infection test values in each individual patient may serve as an adjunctive tool to help diagnose COVID-19 relapse. |
| キーワード | 再燃（relapse） 新型コロナウイルス感染症（COVID-19） 高齢者（elderly） ステロイド（steroids） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2022-12-01 |
| 巻 | 134巻 |
| 号 | 3号 |
| 開始ページ | 171 |
| 終了ページ | 175 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.134.171 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2022 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.134.171 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamase, Yuko| Huang, Hai| Mitoh, Yoshihiro| Egusa, Masahiko| Miyawaki, Takuya| Yoshida, Ryusuke| |
| キーワード | postingestive effects galactose lactose oligosaccharides lactic acid |
| 発行日 | 2023-03-08 |
| 出版物タイトル | Foods |
| 巻 | 12巻 |
| 号 | 6号 |
| 出版者 | MDPI |
| 開始ページ | 1150 |
| ISSN | 2304-8158 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 36981077 |
| DOI | 10.3390/foods12061150 |
| Web of Science KeyUT | 000955624300001 |
| 関連URL | isVersionOf https://doi.org/10.3390/foods12061150 |
| JaLCDOI | 10.18926/AMO/64361 |
|---|---|
| フルテキストURL | 77_1_45.pdf |
| 著者 | Takeuchi, Kazuhiro| Ide, Yasuhiro| Mori, Yuichiro| Uehara, Yusuke| Sukeishi, Hiroshi| Goto, Sachiko| |
| 抄録 | Novel deep learning image reconstruction (DLIR) reportedly changes the image quality characteristics based on object contrast and image noise. In clinical practice, computed tomography image noise is usually controlled by tube current modulation (TCM) to accommodate changes in object size. This study aimed to evaluate the image quality characteristics of DLIR for different object sizes when the in-plane noise was controlled by TCM. Images acquisition was performed on a GE Revolution CT system to investigate the impact of the DLIR algorithm compared to the standard reconstructions of filtered-back projection (FBP) and hybrid iterative reconstruction (hybrid-IR). The image quality assessment was performed using phantom images, and an observer study was conducted using clinical cases. The image quality assessment confirmed the excellent noise- reduction performance of DLIR, despite variations due to phantom size. Similarly, in the observer study, DLIR received high evaluations regardless of the body parts imaged. We evaluated a novel DLIR algorithm by replicating clinical behaviors. Consequently, DLIR exhibited higher image quality than those of FBP and hybrid-IR in both phantom and observer studies, albeit the value depended on the reconstruction strength, and proved itself capable of providing stable image quality in clinical use. |
| キーワード | computed tomography deep learning image reconstruction tube current modulation object size |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-02 |
| 巻 | 77巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 45 |
| 終了ページ | 55 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36849145 |
| Web of Science KeyUT | 000952992100002 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamakawa, Yasuaki| Yamamoto, Norio| Tomita, Yosuke| Okuda, Ryuichiro| Masada, Yasutaka| Shiroshita, Akihiro| Matsumoto, Toshiyuki| |
| キーワード | femoral neck fracture intracapsular hip fracture Garden alignment index posterior tilt inter-rater reliability intra-rater reliability intraclass correlation coefficients |
| 発行日 | 2022-12-27 |
| 出版物タイトル | Journal Of Personalized Medicine |
| 巻 | 13巻 |
| 号 | 1号 |
| 出版者 | MDPI |
| 開始ページ | 53 |
| ISSN | 2075-4426 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 36675714 |
| DOI | 10.3390/jpm13010053 |
| Web of Science KeyUT | 000915393000001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jpm13010053 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Akhtar, Muhammad Shahbaz| Aslam, Sohaib| Ditta, Allah| Albalawi, Bedur Faleh A.| Oki, Yoko| Nakashima, Yoshitaka| |
| キーワード | Azolla biomass bioconcentration factor Cu removal efficiency Cu toxicity translocation factor |
| 発行日 | 2022-12-28 |
| 出版物タイトル | Sustainability |
| 巻 | 15巻 |
| 号 | 1号 |
| 出版者 | MDPI |
| 開始ページ | 497 |
| ISSN | 2071-1050 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/su15010497 |
| Web of Science KeyUT | 000909376900001 |
| 関連URL | isVersionOf https://doi.org/10.3390/su15010497 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Morón-López, Jesús| Vergara, Karen| Sato, Masanao| Gajardo, Gonzalo| Ueki, Shoko| |
| 発行日 | 2022-08-18 |
| 出版物タイトル | PLOS ONE |
| 巻 | 17巻 |
| 号 | 8号 |
| 出版者 | Public Library Science |
| 開始ページ | e0273330 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Morón-López et al. |
| 論文のバージョン | publisher |
| PubMed ID | 35980990 |
| DOI | 10.1371/journal.pone.0273330 |
| Web of Science KeyUT | 000892314200084 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0273330 |
| JaLCDOI | 10.18926/AMO/64117 |
|---|---|
| フルテキストURL | 76_6_673.pdf |
| 著者 | Okazawa-Sakai, Mika| Yamamoto, Yasuko| Futagawa, Mashu| Okamura, Miki| Miyawaki, Satoko| Nishina, Tomohiro| Takehara, Kazuhiro| Kozuki, Toshiyuki| Tomida, Shuta| Hyodo, Ichinosuke| Ohsumi, Shozo| Hirasawa, Akira| |
| 抄録 | Patients found to have presumed germline pathogenic variants (PGPVs) during comprehensive genomic profiling (CGP) require genetic counseling (GC) referrals. We retrospectively investigated the outcomes of patients with PGPVs. Among 159 patients who underwent CGP, we recommended GC for the 16 patients with PGPVs (3 with [FG group] and 13 without [G Group] a family/personal history of hereditary cancer) as well as for the 8 patients with no PGPVs, but a history (F group); 2 (67%), 5 (38%), and 3 (38%) patients received GC in the FG, G, and F groups, respectively. Germline testing results were positive in 1 and 2 patients of the FG and G groups, respectively. Among the patients recommended for GC, 58% did not receive GC due to lack of interest, poor performance status, or death. CGP contributes to the identification of germline variants in patients without a history of hereditary cancer. However, the proportion of patients who undergo GC should be improved. |
| キーワード | comprehensive genomic profiling hereditary cancer germline findings presumed germline pathogenic variant(s) genetic counseling |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 673 |
| 終了ページ | 678 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549769 |
| Web of Science KeyUT | 000905195100007 |
| フルテキストURL | K0006711_abstract_review.pdf K0006711_summary.pdf |
|---|---|
| 著者 | 源田 亜衣| |
| 発行日 | 2022-09-22 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第6711号 |
| 学位授与年月日 | 2022-09-22 |
| 学位・専攻分野 | 博士（理学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/64040 |
|---|---|
| フルテキストURL | 76_5_585.pdf |
| 著者 | Choshi, Haruki| Watanabe, Mototsugu| Furukawa, Shinichi| Ujike, Hiroyuki| Kataoka, Kazuhiko| |
| 抄録 | Pulmonary metastatic resection is a standard therapy for renal cell carcinoma (RCC). Although patients with pulmonary metastases who do not undergo any treatment have poor prognoses, it has been reported that resection for pulmonary metastases yields good clinical outcomes. We investigated the prognoses of the 10 Japanese patients (eight males, two females) who underwent a surgical resection of pulmonary metastasectomy from RCC at our institution between April 1, 2012 and March 31, 2020 and analyzed the prognostic factors. We determined the prognoses and calculated the 5-year overall survival (OS) and disease-free survival (DFS) rates. To identify prognostic factors, we compared the median DFS duration for each factor. Elderly patients (median age, 75.5 years) were more predominant compared to previous studies, and all 10 patients underwent a complete resection. The 5-year DFS rate was 30.5% (95%CI: 0.045-0.63) and the 5-year OS rate was 80% (95%CI: 0.20-0.97). The following factors were associated with better prognosis: female, disease-free interval≥36 months, and metastases size<12 mm. These results indicate that complete resection for pulmonary metastases from RCC resulted in good clinical outcomes, particularly for patients with better prognostic factors. |
| キーワード | renal cell carcinoma pulmonary metastasis complete resection |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 585 |
| 終了ページ | 591 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352806 |
| Web of Science KeyUT | 000884907100012 |
| JaLCDOI | 10.18926/AMO/64033 |
|---|---|
| フルテキストURL | 76_5_527.pdf |
| 著者 | Makihara, Seiichiro| Kariya, Shin| Miyamoto, Shotaro| Uraguchi, Kensuke| Oka, Aiko| Tsumura, Munechika| Noda, Yohei| Ando, Mizuo| Okano, Mitsuhiro| |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 527 |
| 終了ページ | 533 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352799 |
| Web of Science KeyUT | 000884907100005 |
| JaLCDOI | 10.18926/AMO/64032 |
|---|---|
| フルテキストURL | 76_5_519.pdf |
| 著者 | Ishioka, Yoko| Yamashita, Hiroyuki| Hamaguchi, Kinya| Kuwahara, Yoshitaka| Nakamura, Kaoru| Nakatsuka, Mikiya| |
| 抄録 | To examine the outcome of gestational blood pressure and birth weight in women with normal pre-pregnancy BMI (18.5-25 kg/m2) who are at the lower and upper limits of this range, i.e., slightly underweight or slightly overweight. Overall, 2,038 Japanese women with low -risk who had delivered during January 2014–December 2016 were classified according to their pre-pregnancy BMI: underweight (< 18.5 kg/m2), slightly underweight (18.5≤BMI<21 kg/m2), normal (21≤BMI<23 kg/m2), slightly overweight (23≤BMI<25 kg/m2) and overweight (≤ 25 kg/m2). Their blood pressure during each trimester and birth weight was evaluated. The slightly overweight group showed a significantly higher blood pressure than the underweight and slightly underweight groups. Birth weight was lower in the slightly underweight than in the slightly overweight group (p<0.01). The incidence rate of “heavy for dates” (HFD) infants was significantly higher in the slightly overweight and overweight groups than in the other groups (p<0.05 and p<0.01, respectively). Weight gain of < 7 kg significantly increased the rate of “light for dates” (LFD) infants, while a weight gain of ≥13 kg significantly increased the rate of HFD infants (p<0.05 and p<0.01, respectively). Blood pressure during pregnancy was ssociated with pre-pregnancy BMI. The birth weight of infants of low-risk pregnant women is affected by both pre-pregnancy BMI and gestational weight gain. |
| キーワード | birth weight blood pressure normal body weight pregnancy pre-pregnancy BMI |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 519 |
| 終了ページ | 526 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352798 |
| Web of Science KeyUT | 000884907100004 |
| JaLCDOI | 10.18926/AMO/64024 |
|---|---|
| フルテキストURL | 76_5_489.pdf |
| 著者 | Matsumoto, Yuji| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Date, Isao| |
| 抄録 | Glioblastoma (GBM) is a fatal primary malignant brain tumor in adults. Despite decades of research, the prognosis for GBM patients is still disappointing. One major reason for the intense therapeutic resistance of GBM is inter- and intra-tumor heterogeneity. GBM-intrinsic transcriptional profiling has suggested the presence of at least three subtypes of GBM: the proneural, classic, and mesenchymal subtypes. The mesenchymal subtype is the most aggressive, and patients with the mesenchymal subtype of primary and recurrent tumors tend to have a worse prognosis compared with patients with the other subtypes. Furthermore, GBM can shift from other subtypes to the mesenchymal subtype over the course of disease progression or recurrence. This phenotypic transition is driven by diverse tumor-intrinsic molecular mechanisms or microenvironmental factors. Thus, better understanding of the plastic nature of mesenchymal transition in GBM is pivotal to developing new therapeutic strategies. In this review, we provide a comprehensive overview of the current understanding of the elements involved in the mesenchymal transition of GBM and discuss future perspectives. |
| キーワード | glioma glioblastoma mesenchymal subtype mesenchymal transition heterogeneity |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 489 |
| 終了ページ | 502 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352795 |
| Web of Science KeyUT | 000884907100001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kobashi, Mayu| Iwamuro, Masaya| Kuraoka, Sakiko| Inoo, Shoko| Okanoue, Shotaro| Satomi, Takuya| Hamada, Kenta| Abe, Makoto| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Tanaka, Takehiro| Kawahara, Yoshiro| Okada, Hiroyuki| |
| キーワード | familial adenomatous polyposis gastric adenoma gastric cancer phenotypic variations |
| 発行日 | 2022-10-14 |
| 出版物タイトル | Medicine |
| 巻 | 101巻 |
| 号 | 41号 |
| 出版者 | Lippincott Williams & Wilkins |
| 開始ページ | e30997 |
| ISSN | 0025-7974 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 36254079 |
| DOI | 10.1097/MD.0000000000030997 |
| Web of Science KeyUT | 000868085500032 |
| 関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000030997 |
| JaLCDOI | 10.18926/AMO/63892 |
|---|---|
| フルテキストURL | 76_4_385.pdf |
| 著者 | Manabe, Tomotaka| Miyake, Keisuke| Kaji, Yoshio| Ninomiya, Kento| Fujita, Chiaki| Tanaka, Shouichi| Morita, Shin| Tamiya, Takashi| Yamamoto, Tetsuji| |
| 抄録 | The relationship between perioperative clinical course variables and postoperative length of hospital stay (LOS) in patients undergoing primary intracranial meningioma resection has not been fully elucidated. We therefore aimed to identify the perioperative clinical course variables that predict postoperative LOS in such patients. We retrospectively collected data concerning demographics, tumor characteristics, and perioperative clinical course variables in 76 patients who underwent primary intracranial meningioma resection between January 2010 and December 2019, and tested for associations with postoperative LOS. Univariate analyses showed that younger age, fewer days to postoperative initiation of standing/walking, preoperative independence in activities of daily living (ADL), and ADL independence one week after surgery were associated with shorter postoperative LOS. Multiple regression analyses with these factors identified that days to stand/walk initiation and ADL independence one week after surgery were associated with postoperative LOS. Based on these results, we conclude that rehabilitation programs that promote early mobilization and the early acquisition of independence may reduce postoperative LOS in patients who undergo primary intracranial meningioma resection. |
| キーワード | early mobilization functional independence perioperative clinical course length of hospital stay meningioma |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-08 |
| 巻 | 76巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 385 |
| 終了ページ | 390 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36123152 |
| Web of Science KeyUT | 000882167300004 |
| フルテキストURL | fulltext20220908-1.pdf |
|---|---|
| 著者 | Matsuo, Toshihiko| Chaomulige| Miyaji, Mary| Hosoya, Osamu| Saito, Akira| Nakazono, Kazuyuki| |
| キーワード | whole genome sequencing idiopathic superior oblique muscle palsy strabismus esotropia exotropia linkage analysis single nucleotide variations and short insertions/deletions SNVs/InDels SSTR5-AS1 bioinformatics muscle hypoplasia (aplasia) |
| 発行日 | 2022-08-03 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 23巻 |
| 号 | 15号 |
| 出版者 | MDPI AG |
| 開始ページ | 8626 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. |
| 論文のバージョン | publisher |
| PubMed ID | 35955756 |
| DOI | 10.3390/ijms23158626 |
| Web of Science KeyUT | 000838931000001 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms23158626 |
| JaLCDOI | 10.18926/AMO/63407 |
|---|---|
| フルテキストURL | 76_2_137.pdf |
| 著者 | Tsukahara, Masaru| So, Ryuhei| Yada, Yuji| Kodama, Masafumi| Kishi, Yoshiki| Yamada, Norihito| |
| 抄録 | Although reported for Caucasians, changes in plasma clozapine levels after smoking cessation in East Asians remain unclear. We here investigated plasma clozapine levels before and after smoking cessation in Japanese inpatients with schizophrenia. We conducted a retrospective chart review of 14 inpatients with schizophrenia who were being treated with clozapine between June 1, 2019, and July 31, 2019 and who were smokers as of July 1, 2019, the day on which a smoking ban was instituted in the tertiary public psychiatric hospital. The primary outcome was individual differences in plasma clozapine levels between before and after the smoking ban, which were compared using paired t-tests. The mean plasma clozapine level was significantly increased, by 213.4 ng/mL (95% CI 119.9-306.8; p<0.01) or 53.2%. Four of the 14 inpatients experienced clinically significant side effects, such as myoclonus, drooling, and amnesia, due to the development of high plasma clozapine levels. Our findings indicated that close monitoring of plasma clozapine levels before and after smoking cessation and prior dose adjustment of clozapine may be necessary, to prevent a significant risk of developing high plasma clozapine levels, even in Japanese patients. |
| キーワード | Asian clozapine schizophrenia smoking |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-04 |
| 巻 | 76巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 137 |
| 終了ページ | 143 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35503441 |
| Web of Science KeyUT | 000792374900005 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsuoka-Uchiyama, Natsumi| Uchida, Haruhito A.| Okamoto, Shugo| Onishi, Yasuhiro| Katayama, Katsuyoshi| Tsuchida-Nishiwaki, Mariko| Takeuchi, Hidemi| Takemoto, Rika| Hada, Yoshiko| Umebayashi, Ryoko| Kurooka, Naoko| Tsuji, Kenji| Eguchi, Jun| Nakajima, Hirofumi| Shikata, Kenichi| Wada, Jun| |
| 発行日 | 2022-01-10 |
| 出版物タイトル | Journal Of Diabetes Research |
| 巻 | 2022巻 |
| 出版者 | Hindawi Ltd. |
| 開始ページ | 3157841 |
| ISSN | 2314-6745 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Natsumi Matsuoka-Uchiyama et al. |
| 論文のバージョン | publisher |
| PubMed ID | 35047644 |
| DOI | 10.1155/2022/3157841 |
| Web of Science KeyUT | 000774919000001 |
| 関連URL | isVersionOf https://doi.org/10.1155/2022/3157841 |
| フルテキストURL | fulltext20220413-1.pdf FeaturedImage20220413-1.pdf figures20220413-1.pdf tables20220413-1.pdf SI20220413-1.pdf |
|---|---|
| 著者 | Takemura-Uchiyama, Iyo| Tsurui, Hiroki| Shimakura, Hidekatsu| Nasukawa, Tadahiro| Imanishi, Ichiro| Uchiyama, Jumpei| Fukuyama, Tomoki| Sakamoto, Shuji| Morisawa, Keiko| Fujimura, Masato| Murakami, Hironobu| Kanamaru, Shuji| Kurokawa, Kenji| Kawamoto, Keiko| Iyori, Keita| Sakaguchi, Masahiro| |
| キーワード | Staphylococcus pseudintermedius atopic dermatitis IgE dogs DM13-domain-containing protein exacerbation factor |
| 備考 | This is a pre-copyedited, author-produced version of an article accepted for publication in [insert journal title] following peer review. The version of record [insert complete citation information here] is available online at: https://doi.org/10.1093/femsle/fnac019| |
| 発行日 | 2022 |
| 出版物タイトル | FEMS Microbiology Letters |
| 巻 | 369巻 |
| 号 | 1号 |
| 出版者 | Oxford University Press (OUP) |
| 開始ページ | fnac019 |
| ISSN | 1574-6968 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2022. Published by Oxford University Press on behalf of FEMS. |
| 論文のバージョン | author |
| PubMed ID | 35191469 |
| DOI | 10.1093/femsle/fnac019 |
| Web of Science KeyUT | 000764887500001 |
| 関連URL | isVersionOf https://doi.org/10.1093/femsle/fnac019 |
| JaLCDOI | 10.18926/CTED/63318 |
|---|---|
| タイトル（別表記） | Use of Table-Talk Role-Playing Game (TRPG) to Promote Communication Behaviors among Children with ASD |
| フルテキストURL | cted_012_343.pdf |
| 著者 | 木下 豪| 丹治 敬之| |
| 抄録 | 本研究では，自閉スペクトラム症(ASD)または注意欠陥多動性障害(ADHD)のある小学生3名を対象に，テーブルトーク・ロールプレイングゲーム(TRPG)を用いた余暇活動を実施し，児童同士のコミュニケーション行動の変容について検討した。加藤ら(2019)による「いただきダンジョンRPG」において，ゲーム上の場面区分「探索フェイズ」「戦闘フェイズ」が，児童同士の発話量と発話内容にどのような変化をもたらすかについて，実際の活動場面からトランスクリプトを作成して分析した。その結果，児童同士の発話量が「探索フェイズ」「戦闘フェイズ」の両方において増加し，発話内容も多様化した。この結果から，TRPG を用いた余暇活動は，同年代の他者とのコミュニケーションや交流機会の成功体験を蓄積できる活動として，ASD 児にとって有用であることが示唆された。 |
| キーワード | ASD(Autism Spectrum Disorder) TRPG(Table-Talk Role Playing Game) コミュニケーション(Communication) 余暇活動(Leisure Activities) |
| 出版物タイトル | 岡山大学教師教育開発センター紀要 |
| 発行日 | 2022-03-30 |
| 巻 | 12巻 |
| 開始ページ | 343 |
| 終了ページ | 357 |
| ISSN | 2186-1323 |
| 言語 | 日本語 |
| 著作権者 | Copyright © 2022 岡山大学教師教育開発センター |
| 論文のバージョン | publisher |