検索結果 719 件
| JaLCDOI | 10.18926/AMO/66926 |
|---|---|
| フルテキストURL | 78_2_171.pdf |
| 著者 | Kuramoto, Aya| Saito, Shinya| Watanabe, Kumi| |
| 抄録 | We investigated (i) the relationships among internalized stigma (IS), sense of coherence (SOC), and the personal recovery (PR) of persons with schizophrenia living in the community, and (ii) how to improve the support for these individuals. A questionnaire survey on IS, SOC, and PR was sent by mail to 270 persons with schizophrenia living in the community who were using psychiatric daycare services, of whom 149 responded and 140 were included in the analysis. We established a hypothetical model in which IS influences PR, and SOC influences IS and PR, and we used structural equation modeling to examine the relationships among these concepts. The goodness of fit was acceptable. Our findings suggest that rather than directly promoting PR, SOC promotes PR by mitigating the impact of IS. It is important for nurses/supporters to support individuals with schizophrenia living in the community so that they have opportunities to reflect on their own experiences through their activities and to share their experiences with peers. Nurses/supporters themselves should also reflect on their own support needs. Our findings suggest that this will lead to a reduction of IS and the improvement of SOC, which will in turn promote personal recovery. |
| キーワード | schizophrenia internalized stigma sense of coherence personal recovery community |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-04 |
| 巻 | 78巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 171 |
| 終了ページ | 184 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38688835 |
| Web of Science KeyUT | 001229151800009 |
| JaLCDOI | 10.18926/AMO/66925 |
|---|---|
| フルテキストURL | 78_2_163.pdf |
| 著者 | Deguchi, Takayuki| Kanda, Kanae| Furusawa, Kazunari| Nlandu Roger Ngatu| Hirao, Tomohiro| |
| 抄録 | A spinal cord injury (SCI) can cause severe lifelong functional disability and profoundly affect an individual’s daily life. We investigated the prediction of patients’ post-SCI functional outcomes by evaluating sensory scores rather than motor scores, as the latter’s association with functional outcomes is well established. We examined patients’ responses to a light touch (LT) and pin prick (PP) at admission and the response data’s usefulness as predictors of functional outcomes (i.e., ability to perform activities of daily living) at discharge. This exploratory observational study used data from the Japanese National Spinal Cord Injury Database (SCI-J). Data from 3,676 patients who met the inclusion criteria and were admitted for an SCI between 1997 and 2020 were analyzed. The motor score of the Functional Independence Measure (mFIM) at discharge was used as an index of functional outcome. A multiple regression analysis revealed that the mFIM was associated with both the LT response (β=0.07 (0.01), p<0.001) and the PP response (β=0.07 (0.01), p<0.001) at admission. The false discovery rate log-worth values for LT and PP were 6.6 and 8.5, respectively. Our findings demonstrate that LT and PP scores at admission can help predict patients’ functional outcomes after an SCI, although the magnitude of their contributions is not high. |
| キーワード | functional independence measure light touch pin prick spinal cord injury Japanese National Spinal Cord Injury Database |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-04 |
| 巻 | 78巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 163 |
| 終了ページ | 170 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38688834 |
| Web of Science KeyUT | 001229151800008 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Ohsawa, Kumiko| Momose, Shuji| Nishikori, Asami| Nishimura, Midori Filiz| Gion, Yuka| Sawada, Keisuke| Higashi, Morihiro| Tokuhira, Michihide| Tamaru, Jun-Ichi| Sato, Yasuharu| |
| キーワード | classic Hodgkin lymphoma methotrexate immunodeficiency programmed cell death-ligand 1 rheumatoid arthritis |
| 発行日 | 2024-03-27 |
| 出版物タイトル | Cancers |
| 巻 | 16巻 |
| 号 | 7号 |
| 出版者 | MDPI |
| 開始ページ | 1298 |
| ISSN | 2072-6694 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38610976 |
| DOI | 10.3390/cancers16071298 |
| Web of Science KeyUT | 001201068000001 |
| 関連URL | isVersionOf https://doi.org/10.3390/cancers16071298 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kawai, Daisuke| Iwamuro, Masaya| Takenaka, Ryuta| Obata, Taisuke| Yamamoto, Takashi| Hirata, Shoichiro| Miura, Ko| Takemoto, Koji| Tsugeno, Hirofumi| Fujiki, Shigeatsu| |
| キーワード | endoscopic submucosal dissection antithrombotic agents thienopyridine gastric tumor postoperative bleeding delayed bleeding |
| 発行日 | 2024-03-25 |
| 出版物タイトル | Journal of Clinical Medicine |
| 巻 | 13巻 |
| 号 | 7号 |
| 出版者 | MDPI |
| 開始ページ | 1886 |
| ISSN | 2077-0383 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38610651 |
| DOI | 10.3390/jcm13071886 |
| Web of Science KeyUT | 001200991800001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jcm13071886 |
| JaLCDOI | 10.18926/AMO/66913 |
|---|---|
| フルテキストURL | 78_2_107.pdf |
| 著者 | Han, Dongxiang| Du, Jianxiu| Wang, Wei| Wang, Cui| |
| 抄録 | Vertical transmission of hepatitis B virus (HBV), especially in Asia, is a key target in the global elimination of HBV. This study assessed the effects of tenofovir disoproxil fumarate (TDF) in pregnant women for mother-to-infant transmission of HBV. A total of 122 pregnant women at our hospital met the inclusion criteria for high HBV DNA viral loads. They were randomly divided into TDF-treatment (n=70) and placebo (n=52) groups. Maternal liver function and serum HBV DNA load were tested before and after treatment. Clinical and laboratory data of infants were assayed at delivery and 7-months post-partum visit and compared between the two groups. There was no difference in clinical characteristics of participants between the two groups. There were no significant differences in liver function markers, including alanine aminotransferase, total bilirubin, blood creatinine, and blood urea nitrogen levels before and after TDF treatment. The serum HBV DNA viral load of the TDF-treated group became significantly lower than those of the control group and their own pre-medication levels. Infants showed no significant difference in body growth, including weight, height, head size, and five-min Apgar score. At 7 months after birth, 94.29% of infants in the TDF group and 86.54% of control-group infants had protective HBsAb levels ≥ 10 mIU/ml (p>0.05). The HBV infection rate of infants in the TDF-treated group was lower than that in the non-treated group. In high-HBV-DNA-load pregnant women, TDF administered from 28 weeks gestational age to delivery was associated with a lower risk of mother-to-infant transmission of HBV. |
| キーワード | mother-to-infant transmission tenofovir disoproxil fumarate hepatitis B virus |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-04 |
| 巻 | 78巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 107 |
| 終了ページ | 113 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38688828 |
| Web of Science KeyUT | 001229151800002 |
| JaLCDOI | 10.18926/AMO/66912 |
|---|---|
| フルテキストURL | 78_2_095.pdf |
| 著者 | Itano, Junko| Kiura, Katsuyuki| Maeda, Yoshinobu| Miyahara, Nobuaki| |
| 抄録 | The lungs are very complex organs, and the respiratory system performs the dual roles of repairing tissue while protecting against infection from various environmental stimuli. Persistent external irritation disrupts the immune responses of tissues and cells in the respiratory system, ultimately leading to respiratory disease. Neuropeptide Y (NPY) is a 36-amino-acid polypeptide and a neurotransmitter that regulates homeostasis. The NPY receptor is a seven-transmembrane-domain G-protein-coupled receptor with six subtypes (Y1, Y2, Y3, Y4, Y5, and Y6). Of these receptors, Y1, Y2, Y4, and Y5 are functional in humans, and Y1 plays important roles in the immune responses of many organs, including the respiratory system. NPY and the Y1 receptor have critical roles in the pathogenesis of asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. The effects of NPY on the airway immune response and pathogenesis differ among respiratory diseases. This review focuses on the involvement of NPY in the airway immune response and pathogenesis of various respiratory diseases. |
| キーワード | neuropeptide y Y1 receptor airway immune response bronchial epithelial cells respiratory disease |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-04 |
| 巻 | 78巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 95 |
| 終了ページ | 106 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38688827 |
| Web of Science KeyUT | 001229151800001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Takenaka, Ryuta| Miyahara, Koji| Okanoue, Shotaro| Yoshioka, Masao| Sakaguchi, Chihiro| Yamamoto, Kumiko| Kawai, Yoshinari| Toyokawa, Tatsuya| Tanaka, Takehiro| Otsuka, Motoyuki| |
| キーワード | Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue Gastric neoplasms Esophagogastroduodenoscopy t(11;18) translocation, Trisomy 18 |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55663-9| |
| 発行日 | 2024-02-29 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 4953 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38418651 |
| DOI | 10.1038/s41598-024-55663-9 |
| Web of Science KeyUT | 001178149200009 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-024-55663-9 |
| JaLCDOI | 10.18926/ESR/66844 |
|---|---|
| タイトル（別表記） | Petrological characteristics of the stone chamber of Tobiotsuka Kofun, Okayama Prefecture |
| フルテキストURL | esr_030_001_012.pdf |
| 著者 | 金子 峻大| 野坂 俊夫| 清家 章| |
| 抄録 | Tobiotsuka Kofun, a tumulus built on the Misu Hills in the Kofun period, has a horizontal stone chamber made of huge stone blocks with a width up to 2 meters or more. To specify the source of the stone blocks, we carried out the measurement of magnetic susceptibility, petrographic observation, and chemical analysis of minerals. The stones are amphibole-biotite granite with phenocrystic large grains of K-feldspar. The back-wall stone of the chamber has higher magnetic susceptibility than ceiling and side-wall stones, which probably results from a higher amount of magnetite formed by the alteration of biotite in the back-wall stone. Furthermore, the back-wall stone is different from ceiling stone in that it has lower XMg [Mg/(Mg + Fe) mole ratio], lower Al, Ti, and Na + K contents and higher Si contents of amphibole, higher XMg of biotite, and shows a tendency to have higher Na (albite component) contents at rims of plagioclase crystals and lower Ti contents of zircon. These characteristics of the back-wall stone are similar to those of granite exposed in the Koshinzan area about 2 km northeast of Tobiotsuka Kofun, whereas the ceiling and side-wall stones are similar to granite outcrops in the vicinity of Tobiotsuka Kofun, e.g., in the Midoriyama area. It is concluded that the quarry for the back-wall was located at a different place from that for the ceiling and side-wall stones. |
| キーワード | Tobiotsuka Kofun stone chamber granite |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2024-03-31 |
| 巻 | 30巻 |
| 号 | 1号 |
| 開始ページ | 1 |
| 終了ページ | 12 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumura, Kentarou| Onuma, Takafumi| Kondo, Shinji| Noguchi, Hideki| Uchiyama, Hironobu| Yajima, Shunsuke| Sasaki, Ken| Miyatake, Takahisa| |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-50923-6| |
| 発行日 | 2024-01-02 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 67 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38167631 |
| DOI | 10.1038/s41598-023-50923-6 |
| Web of Science KeyUT | 001163663800084 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-023-50923-6 |
| フルテキストURL | fulltext20240311-02.pdf |
|---|---|
| 著者 | Urasaki, Kimiko| Matsumura, Kentarou| Miyatake, Takahisa| |
| キーワード | Diurnal pattern Eggs Mating system Mounting Weevil |
| 備考 | The version of record of this article, first published in Applied Entomology and Zoology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s13355-024-00861-0| |
| 発行日 | 2024-02-21 |
| 出版物タイトル | Applied Entomology and Zoology |
| 巻 | 59巻 |
| 号 | 2号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 117 |
| 終了ページ | 126 |
| ISSN | 0003-6862 |
| NCID | AA00543238 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| DOI | 10.1007/s13355-024-00861-0 |
| Web of Science KeyUT | 001169174500001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s13355-024-00861-0 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Oka, Kosuke| Tokumasu, Kazuki| Hagiya, Hideharu| Otsuka, Fumio| |
| キーワード | C-reactive protein (CRP) fever of unknown origin (FUO) functional hyperthermia (FH) psychiatric disorder psychogenic fever |
| 発行日 | 2024-02-03 |
| 出版物タイトル | Journal of Clinical Medicine |
| 巻 | 13巻 |
| 号 | 3号 |
| 出版者 | MDPI |
| 開始ページ | 889 |
| ISSN | 2077-0383 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38337583 |
| DOI | 10.3390/jcm13030889 |
| Web of Science KeyUT | 001159108700001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jcm13030889 |
| フルテキストURL | fulltext20240226-04.pdf |
|---|---|
| 著者 | Kuribayashi, Tadahiro| Ohashi, Kadoaki| Nishii, Kazuya| Ninomiya, Kiichiro| Tsubata, Yukari| Ishikawa, Nobuhisa| Kodani, Masahiro| Kanaji, Nobuhiro| Yamasaki, Masahiro| Fujitaka, Kazunori| Kuyama, Shoichi| Takigawa, Nagio| Fujimoto, Nobukazu| Kubota, Tetsuya| Inoue, Masaaki| Fujiwara, Keiichi| Harita, Shingo| Takata, Ichiro| Takada, Kenji| Okawa, Sachi| Kiura, Katsuyuki| Hotta, Katsuyuki| |
| キーワード | EGFR EGFR-TKI Lung cancer Immune checkpoint inhibitors Performance status |
| 備考 | The version of record of this article, first published in Journal of Cancer Research and Clinical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00432-024-05618-4| |
| 発行日 | 2024-02-12 |
| 出版物タイトル | Journal of Cancer Research and Clinical Oncology |
| 巻 | 150巻 |
| 号 | 2号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 89 |
| ISSN | 1432-1335 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38347279 |
| DOI | 10.1007/s00432-024-05618-4 |
| Web of Science KeyUT | 001160773600002 |
| 関連URL | isVersionOf https://doi.org/10.1007/s00432-024-05618-4 |
| JaLCDOI | 10.18926/AMO/66673 |
|---|---|
| フルテキストURL | 78_1_071.pdf |
| 著者 | Kaneda, Daisuke| Nishida, Keiichiro| Nasu, Yoshihisa| Nakahara, Ryuichi| Harada, Ryozo| Hotta, Yoshifumi| Naniwa, Shuichi| Ozaki, Toshifumi| |
| 抄録 | We retrospectively investigated the mid-term outcomes of arthroplasty using the AVANTA silicone implant for thumb metacarpophalangeal (MCP) joints with boutonniere deformity in patients with rheumatoid arthritis (RA). This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoperative flexion range of the implant-fracture group were significantly greater than those in the no-implant-fracture group (p=0.039, 0.034, respectively). These results suggest the importance of patient education and careful rehabilitation to prevent excessive flexion. Overall, the AVANTA silicone implant showed a relatively high rate of implant fracture at our institute. |
| キーワード | AVANTA silicone implant boutonniere deformity implant fracture thumb metacarpophalangeal joint arthroplasty rheumatoid arthritis |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 71 |
| 終了ページ | 78 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419317 |
| Web of Science KeyUT | 001203658200011 |
| JaLCDOI | 10.18926/AMO/66672 |
|---|---|
| フルテキストURL | 78_1_063.pdf |
| 著者 | Murakami, Daizo| Nishimoto, Kohei| Takao, Soshi| Miyamaru, Satoru| Kadowaki, Tomoka| Saito, Haruki| Takeda, Hiroki| Ise, Momoko| Suyama, Koichi| Orita, Yorihisa| |
| 抄録 | The tyrosine kinase inhibitor lenvatinib has been confirmed as an effective treatment option for patients with unresectable thyroid carcinoma. We conducted a retrospective analysis of the significance of the effect of continued lenvatinib treatment for the longest duration possible at a reasonable daily dose and with a minimum discontinuation period in 42 patients with unresectable thyroid carcinoma treated with lenvatinib between 2015 and 2020. A Cox proportional hazard model-based analysis revealed that the overall survival of the patients treated with a <8 mg/day mean dose of lenvatinib was significantly better than that of the patients treated with 8-24 mg/day (hazard ratio [HR] 0.38 for 1.14-4.54 mg/day, and HR 0.01 for 4.56-7.97 mg/day) adjusted for various factors (e.g., sex, age, drug interruption period). The cumulative dose of lenvatinib administered tended to be higher in the patients treated with low doses (< 8 mg/day) than in the patients treated with relatively high doses (8-24 mg/day). Considering its adverse events, the continuation of lenvatinib treatment with an adequate daily dose and drug interruption may help prolong the survival of patients with unresectable thyroid carcinoma. |
| キーワード | thyroid carcinoma lenvatinib adverse effect survival |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 63 |
| 終了ページ | 70 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419316 |
| Web of Science KeyUT | 001203658200007 |
| JaLCDOI | 10.18926/AMO/66669 |
|---|---|
| フルテキストURL | 78_1_037.pdf |
| 著者 | Tanaka, Masato| Meena, Umesh| Taoka, Takuya| Fujiwara, Yoshihiro| Yokomizo, Daiichiro| Bashyal, Santosh Kumar| Sake, Naveen| Arataki, Shinya| |
| 抄録 | In adult spinal deformity (ASD) surgery, one of the key factors working to prevent proximal junctional kyphosis is the proximal anchor. The aim of this study was to compare clinical and radiographic outcomes of triangular fixation with conventional fixation as proximal anchoring techniques in ASD surgery. We retrospectively evaluated 54 patients who underwent corrective spinal fusion for ASD. Fourteen patients underwent proximal triangular fixation (Group T; average 74.6 years), and 40 patients underwent the conventional method (Group C; average 70.5 years). Clinical and radiographic outcomes were assessed using visual analogue scale (VAS) values for back pain and the Oswestry disability index (ODI). Radiographic evaluation was also collected preoperatively and postoperatively. Surgical times and intraoperative blood loss of the two groups were not significantly different (493 vs 490 min, 1,260 vs 1,173 mL). Clinical outcomes such as VAS and ODI were comparable in the two groups. Proximal junctional kyphosis in group T was slightly lower than that of group C (28.5% vs 47.5%, p=0.491). However, based on radiology, proximal screw pullout occurred significantly less frequently in the triangular fixation group than the conventional group (0.0% vs 22.5%, p=0.049). Clinical outcomes in the two groups were not significantly different. |
| キーワード | adult spinal deformity proximal junctional kyphosis triangular fixation minimally invasive surgery C arm free |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 37 |
| 終了ページ | 46 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419313 |
| Web of Science KeyUT | 001203658200003 |
| JaLCDOI | 10.18926/AMO/66668 |
|---|---|
| フルテキストURL | 78_1_029.pdf |
| 著者 | Kitayama, Takahiro| Tanaka, Takashi| Kanie, Yuichiro| Marukawa, Yohei| Kojima, Katsuhide| Tanaka, Takehiro| Takao, Soshi| Hiraki, Takao| |
| 抄録 | This retrospective study investigated whether necrotic lesions detected on a computed tomography (CT) scan are more regressive than non-necrotic lesions after methotrexate withdrawal in patients pathologically diagnosed with methotrexate-associated lymphoproliferative disorders (MTX-LPD). In total, 89 lesions extracted from 24 patients on CT scans were included in the analysis. All patients had been evaluated for the presence of necrosis within lesions via CT scan upon first suspicion of MTX-LPD (baseline CT scan). The percentage lesion size reduction between the baseline and initial follow-up CT scan was calculated. The association between necrosis within lesions and size changes was estimated via linear regression analyses using both crude and adjusted models. Necrosis was significantly more common in extranodal lesions (27 out of 30 lesions, 90%) than in nodal lesions (9 out of 59 lesions, 15%, p<0.001). In the crude model, the regression of necrotic lesions was 58.5% greater than that of non-necrotic lesions; the difference was statistically significant (p<0.001). Additionally, the longest diameter of necrotic lesions at the baseline CT scan was significantly greater than that of non-necrotic lesions (p<0.001). Based on the adjusted model, necrotic lesions showed 49.3% greater regression than non-necrotic lesions (p=0.017). Necrosis detected on a CT scan was found to be an independent predictor of regression after MTX withdrawal in patients with MTX-LPD. |
| キーワード | methotrexate lymphoproliferative disorder computed tomography necrosis |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 29 |
| 終了ページ | 36 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419312 |
| Web of Science KeyUT | 001203658200001 |
| JaLCDOI | 10.18926/AMO/66667 |
|---|---|
| フルテキストURL | 78_1_021.pdf |
| 著者 | Tamura, Masanori| Furumatsu, Takayuki| Yokoyama, Yusuke| Kintaka, Keisuke| Higashihara, Naohiro| Kawada, Koki| Ozaki, Toshifumi| |
| 抄録 | The use of various strategies for arthroscopic meniscal repairs to save the meniscus and prevent the progression of knee osteoarthritis has gradually increased. We investigated the frequency of various arthroscopic treatments and the short-term clinical outcomes of symptomatic isolated medial meniscus (MM) injuries. This retrospective observational study included 193 patients (197 knees) who underwent arthroscopic meniscal treatment for isolated MM injuries between January 2016 and April 2019. Arthroscopic meniscal repairs were divided into two groups: transtibial pullout repairs of MM posterior root tears (MMPRTs) and arthroscopic meniscal repairs for other types of MM injuries. MMPRT pullout repair, other meniscal repairs, and partial meniscectomy were performed in 71.0%, 16.8%, and 12.2% of the knees, respectively. The ratio of women to men and the patient age were higher in the pullout-repair group than the meniscal-repair group. The Preoperative Knee Injury and Osteoarthritis Outcome Score subscale (as an index of daily living activities) was significantly lower in the pullout-repair group than the meniscus-repair group. However, no significant differences were observed in these scores among the two groups postoperatively. Our results suggest that familiarity with the diagnosis and treatment of MMPRTs is necessary for orthopedic surgeons to manage isolated MM injuries. |
| キーワード | knee medial meniscus posterior root tear arthroscopy pullout repair |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 21 |
| 終了ページ | 27 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419311 |
| Web of Science KeyUT | 001203658200002 |
| JaLCDOI | 10.18926/AMO/66666 |
|---|---|
| フルテキストURL | 78_1_015.pdf |
| 著者 | Maeda, Reina| Shien, Tadahiko| Takahashi, Mina| Kawada, Kengo| Kajiwara, Yukiko| Kubo, Shinichiro| Takabatake, Daisuke| Ohtani, Shoichiro| Matsuoka, Kinya| Hikino, Hajime| Ogasawara, Yutaka| Taira, Naruto| Osumi, Shozo| Ikeda, Masahiko| Doihara, Hiroyoshi| |
| 抄録 | While local treatment of metastases is considered to be unrelated to prognosis, previous studies have suggested that local treatment of isolated lung metastases may have positive prognostic impact. We designed this prospective cohort study to investigate the clinical situation and its outcomes. We enrolled patients with fewer than 3 lung nodules suspected of being oligometastases after curative breast cancer surgery. Treatments, including local and systemic therapy, were selected by the physician and patient in consultation. The primary outcome was overall survival (OS); secondary outcomes were the efficacy and the safety of the surgery for lung oligometastases. Between May 2015 and May 2019, 14 patients were enrolled. Resection of lung nodules (metastasectomy) was performed in 11 (78.6%) of 14 patients, and one of these cases was diagnosed as primary lung cancer. Metastasectomies were all performed employing video-assisted thoracic surgery (VATS) without perioperative complications. Systemic therapies were administered to all patients except one. The respective 3-year and 5-year OS rates of patients with lung oligometastases were 91.6% and 81.5%, respectively. Progression occurred in 6 patients: 3 of the 10 with metastasectomy and all 3 without this surgical procedure. Lung metastasectomy was worthwhile as a diagnostic evaluation and may provide long-term benefit in some patients. |
| キーワード | oligometastasis breast cancer lung metastasectomy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 15 |
| 終了ページ | 20 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419310 |
| Web of Science KeyUT | 001203658200008 |
| フルテキストURL | fulltext20240206-05.pdf |
|---|---|
| 著者 | Chaomulige| Matsuo, Toshihiko| Sugimoto, Kohei| Miyaji, Mary| Hosoya, Osamu| Ueda, Masashi| Kobayashi, Ryosuke| Horii, Takuro| Hatada, Izuho| |
| キーワード | comitant strabismus MGST2 gene mouse models genetics CRISPR/Cas9 PCR MRI eye morphology neuro-ophthalmology |
| 発行日 | 2024-02-05 |
| 出版物タイトル | Biomedicines |
| 巻 | 12巻 |
| 号 | 2号 |
| 出版者 | MDPI |
| 開始ページ | 370 |
| ISSN | 2227-9059 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38397974 |
| DOI | 10.3390/biomedicines12020370 |
| Web of Science KeyUT | 001174919400001 |
| 関連URL | isVersionOf https://doi.org/10.3390/biomedicines12020370 |
| フルテキストURL | fulltext20240205-01.pdf |
|---|---|
| 著者 | Tokushige, Keisuke| Abe, Takumi| |
| キーワード | C3-N1' bisindoles bromination umpolung rivularin A alkaloid |
| 備考 | This is the peer reviewed version of the following article: [K. Tokushige, T. Abe, Chem. Eur. J. 2024, 30, e202302963. https://doi.org/10.1002/chem.202302963], which has been published in final form at [https://doi.org/10.1002/chem.202302963]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Jan. 2025.| |
| 発行日 | 2024-01-08 |
| 出版物タイトル | Chemistry – A European Journal |
| 巻 | 30巻 |
| 号 | 11号 |
| 出版者 | Wiley |
| 開始ページ | e202302963 |
| ISSN | 0947-6539 |
| NCID | AA11076269 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Wiley-VCH GmbH |
| 論文のバージョン | author |
| PubMed ID | 37988219 |
| DOI | 10.1002/chem.202302963 |
| Web of Science KeyUT | 001142083100001 |
| 関連URL | isVersionOf https://doi.org/10.1002/chem.202302963 |