検索結果 23669 件
| JaLCDOI | 10.18926/49322 |
|---|---|
| フルテキストURL | mfe_047_025_032.pdf |
| 著者 | Nekado, Kenta| Takai, Yusuke| Nogami, Yasuyuki| |
| 抄録 | Pairing–based cryptosystems are well implemented with Ate–type pairing over Barreto–Naehrig (BN) curve. Then, for instance, their securities depend on the difficulty of Discrete Logarithm Problem (DLP) on the so–denoted G3 over BN curve. This paper, in order to faster solve the DLP, first proposes to utilize Gauss period Normal Basis (GNB) for Pollard’s rho method, and then considers to accelerate the solving by an adoption of lazy random walk, namely tag tracing technique proposed by Cheon et al. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2013-01 |
| 巻 | 47巻 |
| 開始ページ | 25 |
| 終了ページ | 32 |
| ISSN | 1349-6115 |
| 言語 | 英語 |
| 著作権者 | Copyright © by the authors |
| 論文のバージョン | publisher |
| NAID | 120005232374 |
| JaLCDOI | 10.18926/49321 |
|---|---|
| フルテキストURL | mfe_047_019_024.pdf |
| 著者 | Nogami, Yasuyuki| Sumo, Taichi| |
| 抄録 | Recent efficient pairings such as Ate pairing use two efficient rational point subgroups such that π(P) = P and π(Q) = [p]Q, where π, p, P, and Q are the Frobenius map for rational point, the characteristic of definition field, and torsion points for pairing, respectively. This relation accelerates not only pairing but also pairing–related operations such as scalar multiplications. It holds in the case that the embedding degree k divides r − 1, where r is the order of torsion rational points. Thus, such a case has been well studied. Alternatively, this paper focuses on the case that the degree divides r + 1 but does not divide r − 1. Then, this paper shows a multiplicative representation for r–torsion points based on the fact that the characteristic polynomial f(π) becomes irreducible over Fr for which π also plays a role of variable. |
| キーワード | pairing–friendly curve torsion point group structure rank |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2013-01 |
| 巻 | 47巻 |
| 開始ページ | 19 |
| 終了ページ | 24 |
| ISSN | 1349-6115 |
| 言語 | 英語 |
| 著作権者 | Copyright © by the authors |
| 論文のバージョン | publisher |
| NAID | 120005232373 |
| JaLCDOI | 10.18926/49320 |
|---|---|
| フルテキストURL | mfe_047_001_018.pdf |
| 著者 | Kanatani, Kenichi| |
| 抄録 | We summarize techniques for optimal geometric estimation from noisy observations for computer vision applications. We first discuss the interpretation of optimality and point out that geometric estimation is different from the standard statistical estimation. We also describe our noise modeling and a theoretical accuracy limit called the KCR lower bound. Then, we formulate estimation techniques based on minimization of a given cost function: least squares (LS), maximum likelihood (ML), which includes reprojection error minimization as a special case, and Sampson error minimization. We describe bundle adjustment and the FNS scheme for numerically solving them and the hyperaccurate correction that improves the accuracy of ML. Next, we formulate estimation techniques not based on minimization of any cost function: iterative reweight, renormalization, and hyper-renormalization. Finally, we show numerical examples to demonstrate that hyper-renormalization has higher accuracy than ML, which has widely been regarded as the most accurate method of all. We conclude that hyper-renormalization is robust to noise and currently is the best method. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2013-01 |
| 巻 | 47巻 |
| 開始ページ | 1 |
| 終了ページ | 18 |
| ISSN | 1349-6115 |
| 言語 | 英語 |
| 著作権者 | Copyright © by the authors |
| 論文のバージョン | publisher |
| NAID | 120005232372 |
| JaLCDOI | 10.18926/OER/49317 |
|---|---|
| タイトル（別表記） | Survey of Studies in Hindrance(Resistance) to Organizational Change: Focus on its Factor, Mechanism, Elimination. (the second half) |
| フルテキストURL | oer_044_4_021_040.pdf |
| 著者 | 松田 陽一| |
| 抄録 | Organizational change is important topics in organizational behavior. This paper aims to survey of studies in hindrance(resistance) to organizational change. Especially, we focus on its factor, mechanism, and elimination. And so, we suevey previous studies from viewpoint of ①macro organizational theory＇s arguments(Ma. O), ②micro organizational theory＇s arguments(Mi. O), ③social psychology theory＇s arguments(S. P), ④consultant's suggestion(C. S). This paper's important points are as follows: ①factor are various: organizational inertia, action, information＇ flow(Ma. O), loss, stress, trust, recognition, learning(Mi. O), resistance, worry, self-defense(S. P), failure and behavior(8 factors), restrictive functions in equilibrium(10 problems), barrier(C. S). ②Mechanism are various: organizational inertia, action(Ma. O), loss and compusion, recognition(schema, conflict), organizational culture change(Mi. O), driving force and resistance force, influence and balance(S. P). damage, crisis andadherence(C. S). ③Elimination: organizational inertia, adaptation and balance, restraint, adjustment(Ma. O), participation, reward system, vision(Mi. O), participation, job design, taking turns, persuasion(S. P), paticipation, commitment, many eliminated methods(C. S). Addtionaly, our problems are as follows; ①significance of discussion and ②promotion factor in organizational change. And ③rationality, ④measuring method, ⑤practicing to management in organizational change. |
| 出版物タイトル | 岡山大学経済学会雑誌 |
| 発行日 | 2013-02-20 |
| 巻 | 44巻 |
| 号 | 4号 |
| 開始ページ | 21 |
| 終了ページ | 40 |
| ISSN | 0386-3069 |
| 言語 | 日本語 |
| 著作権者 | Copyright © 2013 岡山大学経済学会 |
| 論文のバージョン | publisher |
| NAID | 120005232370 |
| JaLCDOI | 10.18926/49295 |
|---|---|
| タイトル（別表記） | “ 神（Shen）” in the Zhu Xi Philosophy |
| フルテキストURL | bhe_008_123_142.pdf |
| 著者 | 孫 路易| |
| 抄録 | 本稿では、朱子鬼神論の、「在天の鬼神」と「在人の鬼神」及び「祭祀の鬼神」という三 つの内容について考察し検討を加えて、朱子のいう鬼神・神とは何かを探究する。 「在天の鬼神」では、鬼神に、自然現象と気の作用・働きとの二つの意味を与えつつ気の 作用・働きとする方向に収斂している。神も気の作用・働きであるが、鬼神は可視的な痕 跡を残すのに対して、神は痕跡を残さない。神は、生気・生意とされているが、物を生ず る過程または無くす過程のその両過程のどちらにおいても作用するものだから、気の聚と 散の両運動を支える力と推察される。 「在人の鬼神」では、鬼神は魂魄と言い換えられている。魂魄は、ある特定の事象を指し ていう語よりもむしろ二項対立または相対する事項を示す概念である。魂は、呼吸する気、 身体の動き、「思慮・計画」などの心の働き、などの諸義を併せ持つのであるが、これに対 して、魄には、躯体血肉、耳や目などの器官の働き、「記憶・弁別」などの心の働き、など の諸義が与えられている。魄は、体内に内在する身体活動の源としての力、つまり生命力 をも意味する。魂魄、神、精神は同義の概念とされている。 「祭祀の鬼神」では、鬼神は主に天地山川の神霊や先祖の霊魂などを指して言うものであ るが、祭祀論においては、特に人が死んで散じた気つまり散じた魂魄を指して言うもので ある。祭祀は、子孫が、祭りを行い、誠敬を尽くして、先祖の既に散じた気、つまり散じ た魂と魄を招き寄せて結合させる行為である。この魂魄は、神であって気の作用・働きで あるが、また「気の精英」と称される凝固しても形質を形成しない極めて清らかな気でもある。 |
| キーワード | 鬼神 神 魂魄 精神 造化 生気 気の精英 気 理 形而上 |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2012-12-31 |
| 巻 | 8巻 |
| 開始ページ | 123 |
| 終了ページ | 142 |
| ISSN | 1881-5952 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005232352 |
| JaLCDOI | 10.18926/49293 |
|---|---|
| タイトル（別表記） | Student Exchange Program with University of Shanghai for Science and Technology - Present and Future |
| フルテキストURL | bhe_008_081_102.pdf |
| 著者 | 加治 敏之| 酒井 峰男| |
| 抄録 | 岡山大学と上海理工大学との交流の一環として、相互に研修生を派遣する語学文化研修 プログラムが始まって二年になろうとしている。独自に築きあげた日本語教授法を中心に 本プログラムを紹介し、今後の展望についても論ずる。 |
| キーワード | 交流プロジェクト 日本語能力 コースデザイン プロジェクトワーク 短期語学文化研修 |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2012-12-31 |
| 巻 | 8巻 |
| 開始ページ | 81 |
| 終了ページ | 102 |
| ISSN | 1881-5952 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005232350 |
| JaLCDOI | 10.18926/AMO/49259 |
|---|---|
| フルテキストURL | 67_1_65.pdf |
| 著者 | Sakata, Kenichiro| Furumatsu, Takayuki| Abe, Nobuhiro| Miyazawa, Shinichi| Sakoma, Yoshimasa| Ozaki, Toshifumi| |
| 抄録 | Bone marrow-stimulating techniques such as microfracture and subchondral drilling are valuable treatments for full-thickness cartilage defects. However, marrow stimulation-derived reparative tissues are not histologically well-documented in human osteoarthritis. We retrospectively investigated cartilage repairs after marrow stimulation for the treatment of large cartilage defects in osteoarthritic knees. Tissues were obtained from patients who underwent total knee arthroplasty (TKA) after arthroscopic marrow stimulation in medial compartmental osteoarthritis. Clinical findings and cartilage repair were assessed. Sections of medial femoral condyles were histologically investigated by safranin O staining and anti-type II collagen antibody. Marrow stimulation decreased the knee pain in the short term. However, varus leg alignment gradually progressed, and TKA conversions were required. The grade of cartilage repair was not improved. Marrow stimulations resulted in insufficient cartilage regeneration on medial femoral condyles. Safranin O-stained proteoglycans and type II collagen were observed in the deep zone of marrow-stimulated holes. This study demonstrated that marrow stimulation resulted in failed cartilage repair for the treatment of large cartilage defects in osteoarthritic knees. Our results suggest that arthroscopic marrow stimulation might not improve clinical symptoms for the long term in patients suffering large osteoarthritic cartilage defects. |
| キーワード | bone marrow stimulation microfracture subchondral drilling osteoarthritis of the knee cartilage repair |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 65 |
| 終了ページ | 74 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439511 |
| Web of Science KeyUT | 000316829900009 |
| JaLCDOI | 10.18926/AMO/49258 |
|---|---|
| フルテキストURL | 67_1_61.pdf |
| 著者 | Tachibana, Tomoyasu| Orita, Yorihisa| Fujisawa, Masayoshi| Ogawara, Yuya| |
| 抄録 | Thyroid carcinomas arising from ectopic thyroid tissue are uncommon;most of them arise from thyroid tissue in thyroglossal cysts. A rare case of a 66-year-old woman with papillary thyroid carcinoma arising from median ectopic thyroid tissue lacking a thyroglossal duct remnant is reported. The tumor was resected by Sistrunk's procedure, and the patient's postoperative course was good. |
| キーワード | ectopic thyroid papillary thyroid carcinoma thyroglossal duct remnant |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 61 |
| 終了ページ | 64 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439510 |
| Web of Science KeyUT | 000316829900008 |
| JaLCDOI | 10.18926/AMO/49257 |
|---|---|
| フルテキストURL | 67_1_55.pdf |
| 著者 | Shimo, Tsuyoshi| Nishiyama, Akiyoshi| Jinno, Tokiari| Sasaki, Akira| |
| 抄録 | In this article, we report the successful surgical treatment of a patient, 34 years of age, who had a severe gummy smile and a class II malocclusion. The patient had an 11-mm gingival exposure during full smile and a convex profile. A LeFort I osteotomy combined with a horseshoe osteotomy was used for the superior repositioning of the maxilla;then, an intraoral vertical ramus osteotomy (IVRO) and genioplasty were performed for mandibular advancement. The maxilla was acceptably impacted 8mm at the first incisor and 5mm at the first molar. Both the occlusion and facial appearance were significantly improved by this surgical-orthodontic treatment. Our results suggest that the combination of a horseshoe osteotomy with a LeFort I osteotomy is a useful technique for reliable superior repositioning of the maxilla. |
| キーワード | LeFort I osteotomy horseshoe osteotomy gummy smile |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 55 |
| 終了ページ | 60 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439509 |
| Web of Science KeyUT | 000316829900007 |
| JaLCDOI | 10.18926/AMO/49256 |
|---|---|
| フルテキストURL | 67_1_45.pdf |
| 著者 | Hashizume, Hiroaki| Sato, Ken| Yamazaki, Yuichi| Horiguchi, Norio| Kakizaki, Satoru| Mori, Masatomo| |
| 抄録 | In patients with nonalcoholic steatohepatitis (NASH), the prevalence of cirrhosis is higher among women than men, and hepatocellular carcinoma (HCC) develops mainly in the cirrhotic stage among women. However, the long-term outcomes in female patients with NASH have not been fully elucidated, and age, gender and BMI were not simultaneously adjusted in previous studies on the prognosis of NASH. To elucidate the outcomes in female patients with NASH, we prospectively compared NASH patients with advanced fibrosis (advanced NASH) with hepatitis C virus-related advanced fibrosis (advanced CHC) patients and NASH patients with mild fibrosis (mild NASH) using study cohorts that were adjusted for body mass index (BMI) in addition to age. The median follow-up period was 92.5 months. Liver-related complication-free survival was significantly reduced in the advanced NASH group compared to the mild NASH group. No liver-related complications developed in the mild NASH group. The overall survival, liver-related complication- and cardiovascular/cerebrovascular disease-free survival were not significantly different between the advanced NASH and CHC groups. Female patients with NASH and advanced fibrosis may have a less favorable prognosis for liver-related complications than the matched cohorts with NASH and mild fibrosis, but may have a similar prognosis to the matched cohorts with CHC. |
| キーワード | nonalcoholic steatohepatitis chronic hepatitis C prognosis female |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 45 |
| 終了ページ | 53 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439508 |
| Web of Science KeyUT | 000316829900006 |
| JaLCDOI | 10.18926/AMO/49255 |
|---|---|
| フルテキストURL | 67_1_35.pdf |
| 著者 | Watanabe, Masutaka| Arita, Seizaburo| Hashizume, Hiroyuki| Honda, Mitsugi| Nishida, Keiichiro| Ozaki, Toshifumi| |
| 抄録 | The purpose of this study was to quantitatively evaluate Akahori's preoperative classification of cubital tunnel syndrome. We analyzed the results for 57 elbows that were treated by a simple decompression procedure from 1997 to 2004. The relationship between each item of Akahori's preoperative classification and clinical stage was investigated based on the parameter distribution. We evaluated Akahori's classification system using multiple regression analysis, and investigated the association between the stage and treatment results. The usefulness of the regression equation was evaluated by analysis of variance of the expected and observed scores. In the parameter distribution, each item of Akahori's classification was mostly associated with the stage, but it was difficult to judge the severity of palsy. In the mathematical evaluation, the most effective item in determining the stage was sensory conduction velocity. It was demonstrated that the established regression equation was highly reliable (R＝0.922). Akahori's preoperative classification can also be used in postoperative classification, and this classification was correlated with postoperative prognosis. Our results indicate that Akahori's preoperative classification is a suitable system. It is reliable, reproducible and well-correlated with the postoperative prognosis. In addition, the established prediction formula is useful to reduce the diagnostic complexity of Akahori's classification. |
| キーワード | cubital tunnel syndrome ulnar nerve Akahoriʼs classification multiple regression analysis |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 35 |
| 終了ページ | 44 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439507 |
| Web of Science KeyUT | 000316829900005 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/50647 |
| JaLCDOI | 10.18926/AMO/49254 |
|---|---|
| フルテキストURL | 67_1_25.pdf |
| 著者 | Ika, Katsuhiko| Suzuki, Etsuji| Mitsuhashi, Toshiharu| Takao, Soshi| Doi, Hiroyuki| |
| 抄録 | The purpose of this study was to examine the association between shift work and diabetes mellitus by separating shift workers according to the intensity of their shift work (seasonal shift work and continuous shift work). Between May and October 2009, we collected data from annual health checkups and questionnaires at a manufacturing company in Shizuoka, Japan. Questionnaires were returned by 1,601 workers (response rate:96.2%, men/women＝1,314/287). Diabetes mellitus was defined as hemoglobin A1c≥6.5% and fasting blood sugar≥126mg/dl. After exclusions, which included all the women and clerical workers because they did not work in shifts, we analyzed 475 skilled male workers. After adjusting for age, smoking status, frequency of alcohol consumption, and cohabitation status, odds ratios for diabetes mellitus were 0.98 (95% confidence interval [CI]:0.28-4.81) and 2.10 (95% CI:0.77-5.71) among seasonal shift workers and continuous shift workers, respectively, compared with non-shift workers. In an age-stratified analysis (＜45 years vs.≥45 years), the association between continuous shift work and diabetes mellitus was more pronounced among older participants. Compared with non-shift workers, the risk of diabetes mellitus was increased among continuous shift workers, whereas its effect is limited among seasonal shift workers. |
| キーワード | cross-sectional study diabetes mellitus intensity Japan shift work |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 25 |
| 終了ページ | 33 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439506 |
| Web of Science KeyUT | 000316829900004 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/50693 |
| JaLCDOI | 10.18926/AMO/49253 |
|---|---|
| フルテキストURL | 67_1_19.pdf |
| 著者 | Furukawa, Masashi| Soh, Junichi| Yamamoto, Hiromasa| Ichimura, Kouichi| Shien, Kazuhiko| Maki, Yuho| Muraoka, Takayuki| Tanaka, Norimitsu| Ueno, Tsuyoshi| Asano, Hiroaki| Tsukuda, Kazunori| Toyooka, Shinichi| Miyoshi, Shinichiro| |
| 抄録 | Nuclear factor of κ-light polypeptide gene enhancer in B cells inhibitor α (NFKBIA), which is a tumor suppressor gene, was found to be silenced in lung adenocarcinomas. We examined NFKBIA expression, mutations in the EGFR and K-ras genes, and EML4-ALK fusion in 101 resected lung adenocarcinoma samples from never-smokers. NFKBIA expression was evaluated using immunohistochemistry. NFKBIA expression was negative in 16 of the 101 samples (15.8%). EGFR and K-ras mutations and EML4-ALK fusion were detected in 61 (60.5%), 1 (1.0%), and 2 (2.0%) of the 101 samples, respectively, in a completely mutually exclusive manner. Negative NFKBIA expression was observed significantly more frequently among the tumors with none of the three genetic alterations compared to those with such alterations (p＝0.009). In addition, negative NFKBIA expression was significantly more frequent among the EGFR-wild type samples compared to the EGFR-mutant samples (p＝0.013). In conclusion, NFKBIA expression was silenced in adenocarcinomas without EGFR/K-ras mutations or EML4-ALK fusion, suggesting that the silencing of NFKBIA may play an important role in the carcinogenesis of adenocarcinomas independent of EGFR/K-ras mutations or EML4-ALK fusion. |
| キーワード | never-smoker lung cancer adenocarcinoma nuclear factor of κ-light polypeptide gene enhancer in B cells inhibitor α epidermal growth factor receptor |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 19 |
| 終了ページ | 24 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439505 |
| Web of Science KeyUT | 000316829900003 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52534 |
| JaLCDOI | 10.18926/AMO/49252 |
|---|---|
| フルテキストURL | 67_1_9.pdf |
| 著者 | Fatmawati, Ni Nengah Dwi| Sakaguchi, Yoshihiko| Suzuki, Tomonori| Oda, Masataka| Shimizu, Kenta| Yamamoto, Yumiko| Sakurai, Jun| Matsushita, Osamu| Oguma, Keiji| |
| 抄録 | Clostridium botulinum type C and D strains recently have been found to produce PLC on egg yolk agar plates. To characterize the gene, enzymatic and biological activities of C. botulinum PLCs (Cb-PLCs), the cb-plc genes from 8 strains were sequenced, and 1 representative gene was cloned and expressed as a recombinant protein. The enzymatic and hemolytic activities of the recombinant Cb-PLC were measured and compared with those of the Clostridium perfringens alpha-toxin. Each of the eight cb-plc genes encoded a 399 amino acid residue protein preceded by a 27 residue signal peptide. The protein consists of 2 domains, the N- and C-domains, and the overall amino acid sequence identity between Cb-PLC and alpha-toxin was greater than 50%, suggesting that Cb-PLC is homologous to the alpha-toxin. The key residues in the N-domain were conserved, whereas those in the C-domain which are important in membrane interaction were different than in the alpha-toxin. As expected, Cb-PLC could hydrolyze egg yolk phospholipid, p-nitrophenylphosphorylcholine, and sphingomyelin, and also exhibited hemolytic activity;however, its activities were about 4- to over 200-fold lower than those of alpha-toxin. Although Cb-PLC showed weak enzymatic and biological activities, it is speculated that Cb-PLC might play a role in the pathogenicity of botulism or for bacterial survival. |
| キーワード | botulinum phospholipase C botulinum toxin phospholipase C activity sphingomyelinase activity hemolytic activity |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 9 |
| 終了ページ | 18 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439504 |
| Web of Science KeyUT | 000316829900002 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/49731 |
| JaLCDOI | 10.18926/AMO/49251 |
|---|---|
| フルテキストURL | 67_1_1.pdf |
| 著者 | Nishimori, Hisakazu| Maeda, Yoshinobu| Tanimoto, Mitsune| |
| 抄録 | Graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem cell transplantation. Chronic GVHD often presents with clinical manifestations that resemble those observed in autoimmune diseases. Standard treatment is 1-2mg/kg/day of prednisone or an equivalent dose of methylprednisolone, with continued administration of a calcineurin inhibitor for steroid sparing. However, the prognosis of steroid-refractory chronic GVHD remains poor. Classically, chronic GVHD was said to involve predominantly Th2 responses. We are now faced with a more complex picture, involving possible roles for thymic dysfunction, transforming growth factor-β (TGF-β) and platelet-derived growth factor (PDGF), B cells and autoantibodies, and Th1/Th2/Th17 cytokines, as well as regulatory T cells (Tregs), in chronic GVHD. More detailed research on the pathophysiology of chronic GVHD may facilitate the establishment of novel strategies for its prevention and treatment. |
| キーワード | chronic GVHD Th17 Am80 regulatory T cell (Treg) steroid-refractory |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-02 |
| 巻 | 67巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 8 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23439503 |
| Web of Science KeyUT | 000316829900001 |
| 著者 | Department of Earth Sciences, Faculty of Science, Okayama University| |
|---|---|
| 発行日 | 2012-12-26 |
| 出版物タイトル | Okayama University Earth Science Report |
| 巻 | 19巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| 著者 | Department of Earth Sciences, Faculty of Science, Okayama University| |
|---|---|
| 発行日 | 2012-12-26 |
| 出版物タイトル | Okayama University Earth Science Report |
| 巻 | 19巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| JaLCDOI | 10.18926/ESR/49212 |
|---|---|
| タイトル（別表記） | A case study on persistent appearance of the ensemble of precipitation bands in the warm sector of the Baiu front in the western Japan around 19 June 2001 |
| フルテキストURL | esr_019_1_039_050.pdf |
| 著者 | 合田 泰弘| 加藤 内藏進| 塚本 修| |
| 抄録 | A case study on persistent appearance of the ensemble of precipitation bands in the warm sector of the Baiu front in Kyushu District, the western part of Japan around 19 June 2001 was performed based on the operational observational data. Around 00UTC (09JST) 19 June when the Baiu front on the surface weather map was still located about a few 100kms to the north of Kyushu, the number and the total area of the meso-β or γ-scale line-shaped precipitation bands increased around Kyushu rapidly. These precipitation bands had been sustained there and gradually gathered each other to change into the Baiu frontal precipitation zone extending from the northern Kyushu to Seto-Naikai (Seto Inland Sea) around 09UTC (18JST) 19 June (the intense rainfall zone was still located in the warm sector of the Baiu front). Until ~09UTC (18JST) 19 June, the moist air flow with the latently unstable stratification had been sustained around Kyushu corresponding to the low-level southerly wind toward the surface Baiu front to the north of Kyushu. This large-scale situation would contribute greatly to the maintenance of the ensemble of the line-shaped precipitation bands in the warm sector of the Baiu front. |
| キーワード | ensemble of line-shaped precipitation bands precipitation in the warm sector of the Baiu front Baiu fronal rainfall |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2012-12-26 |
| 巻 | 19巻 |
| 号 | 1号 |
| 開始ページ | 39 |
| 終了ページ | 50 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005232330 |
| JaLCDOI | 10.18926/ESR/49211 |
|---|---|
| タイトル（別表記） | The oldest fossil forest in Japan discovered from the Upper Triassic Nariwa Group, Okayama Prefecture, SW Japan -Implication for reconstruction of depositional environment and paleovegetation- |
| フルテキストURL | esr_019_1_025_037.pdf |
| 著者 | 湯川 弘一| 寺田 和雄| 孫 革| 鈴木 茂之| |
| 抄録 | Erect fossil stumps were found from the outcrop of the Upper Triassic Hinabata Formation, the uppermost part of the Nariwa Group at Hinabata, Nariwa-cho,Takahashi City, Okayama Prefecture, SW Japan. They are evidence of the oldest fossil forest in Japan. The Upper Triassic Nariwa Group is mostly composed of non-marine deposits except the marine Jito Formation and characterized by the abundance in plant fossils. The marine Jito Formation is characterized by occurrence of Norian Monotis ochotica. On the basis of detailed observation of the occurrence of erect fossil stumps, as well as sedimentary facies of fossil-bearing unit, the fossil forest was interpreted to have grown on the top of the natural-levee units. One of the erect fossil stumps was identified as Xenoxylon sp. |
| キーワード | erect fossil stump fossil forest Nariwa Group Upper Triassic Xenoxylon |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2012-12-26 |
| 巻 | 19巻 |
| 号 | 1号 |
| 開始ページ | 25 |
| 終了ページ | 37 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005232329 |
| JaLCDOI | 10.18926/ESR/49210 |
|---|---|
| タイトル（別表記） | Estimation of SPM concentration distribution over the central Seto Inland Sea |
| フルテキストURL | esr_019_1_019_024.pdf |
| 著者 | 海老 貴宏| 松本 宏文| 山川 純次| |
| 抄録 | Ordinary Kriging, OK, and Regression Kriging, RK, are the spatial statistical methods that are possible to estimate a horizontal distribution in a study area from discrete data. OK is the method which takes account of only spatial auto-correlation structure of the data, while RK is the method which takes account of an interrelationship between spatial auto-correlation structure and some auxiliary variables to minimize the estimation error. Analytical processing for OK and RK methods was performed by the R-Language (R Core Team, 2012) and its some additional libraries. The auxiliary variables required to perform RK method were prepared by a GIS application, Quantum GIS (Quantum GIS Development Team, 2012). The 3-dimensional geographic representation of the estimation maps was performed by the Google Earth (Google, 2012). In this report, OK and RK methods were applied to one of the Earth scientific information, SPM (Supended Particulate Matter). Then, these methods were considered by comparing two estimation maps, and finally considered qualitatively by displaying these maps in the Google Earth. |
| キーワード | Ordinary Kriging Regression Kriging Auxiliary variable R-Language Google Earth |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2012-12-26 |
| 巻 | 19巻 |
| 号 | 1号 |
| 開始ページ | 19 |
| 終了ページ | 24 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005232328 |