このエントリーをはてなブックマークに追加


ID 13766
Eprint ID
13766
フルテキストURL
106_743.pdf 371 KB
タイトル(別表記)
Studies on the occurrence of bronchial asthma Part 2. Lymphocytes activated by Cytomegalovirus
著者
岡本 誠 岡山大学医学部第二内科学教室
抄録
The possible role of virus infection in the occurrence and attack of asthma was examined by measuring the lymphocyte transformation test to CMV in 44 asthmatic and 14 healthy subjects and analyzed their relation to the clinical parameters. CMV-induced lymphocyte reactivity (CMV-LR) in adult asthmatics was significantly higher than that in the healthy controls. A positive correlation was observed between CMV-LR titer and CMV-complement fixation (CMV-CF) antibody titers (r=0.35). In adult asthmatics, the CMV-LR in the high IgE titer (100U/ml≦) group was significantly higher than that in the low IgE titer (<100U/ml) group. These findings suggest that CMV is an important factor in the pathogenesis of adult asthma mediated by lymphocytes and probably IgE, although the precise mechanism in still unknown.
キーワード
bronchial asthma
viral infection
Cytomegalovirus
IgE
CMV-LTT
備考
原著
発行日
1994-08
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
106巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
743
終了ページ
750
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/106/7-8/106_7-8_743/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
日本語
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma