検索結果 - 岡山大学学術成果リポジトリ

Nintedanib can be used safely and effectively for idiopathic pulmonary fibrosis with predicted forced vital capacity <= 50%: A multi-center retrospective analysis

フルテキストURL	fulltext.pdf
著者	Senoo, Satoru\| Miyahara, Nobuaki\| Taniguchi, Akihiko\| Oda, Naohiro\| Itano, Junko\| Higo, Hisao\| Hara, Naofumi\| Watanabe, Hiromi\| Kano, Hirohisa\| Suwaki, Toshimitsu\| Fuchimoto, Yasuko\| Kajimoto, Kazuhiro\| Ichikawa, Hirohisa\| Kudo, Kenichiro\| Shibayama, Takuo\| Tanimoto, Yasushi\| Kuyama, Shoichi\| Kanehiro, Arihiko\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Okayama Respiratory Disease Study Group (ORDSG)\|
発行日	2020-08-27
出版物タイトル	PLoS ONE
巻	15巻
号	8号
出版者	Public Library of Science
開始ページ	e0236935
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 Senoo et al.
論文のバージョン	publisher
PubMed ID	32853277
DOI	10.1371/journal.pone.0236935
Web of Science KeyUT	000566948800009
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0236935

Three-dimensional observation and analysis of remineralization in dentinal caries lesions

フルテキストURL	fulltext.pdf
著者	Yoshihara, Kumiko\| Nagaoka, Noriyuki\| Nakamura, Akiko\| Hara, Toru\| Hayakawa, Satoshi\| Yoshida, Yasuhiro\| Van Meerbeek, Meerbeek, Bart\|
発行日	2020-03-09
出版物タイトル	Scientific Reports
巻	10巻
号	1号
出版者	Nature
開始ページ	4387
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2020
論文のバージョン	publisher
PubMed ID	32152430
DOI	10.1038/s41598-020-61111-1
Web of Science KeyUT	000563353700001
関連URL	isVersionOf https://doi.org/10.1038/s41598-020-61111-1

Precise MEP monitoring with a reduced interval is safe and useful for detecting permissive duration for temporary clipping

フルテキストURL	fulltext.pdf
著者	Kameda, Masahiro\| Hishikawa, Tomohito\| Hiramatsu, Masafumi\| Yasuhara, Takao\| Kurozumi, Kazuhiko\| Date, Isao\|
キーワード	Stroke
発行日	2020-02-26
出版物タイトル	Scientific Reports
巻	10巻
号	1号
出版者	Nature
開始ページ	3507
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2020
論文のバージョン	publisher
PubMed ID	32103082
DOI	10.1038/s41598-020-60377-9
Web of Science KeyUT	000563210400001
関連URL	isVersionOf https://doi.org/10.1038/s41598-020-60377-9

Multi-drug therapy for epilepsy influenced bispectral index after a bolus propofol administration without affecting propofol's pharmacokinetics: a prospective cohort study

フルテキストURL	fulltext.pdf
著者	Kodama, Matsuri\| Higuchi, Hitoshi\| Ishii-Maruhama, Minako\| Nakano, Mai\| Honda-Wakasugi, Yuka\| Maeda, Shigeru\| Miyawaki, Takuya\|
キーワード	Drug regulation Phase IV trials
発行日	2020-01-31
出版物タイトル	Scientific Reports
巻	10巻
号	1号
出版者	Nature
開始ページ	1578
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2020
論文のバージョン	publisher
PubMed ID	32005870
DOI	10.1038/s41598-020-58460-2
Web of Science KeyUT	000562877500004
関連URL	isVersionOf https://doi.org/10.1038/s41598-020-58460-2

Disseminated Mycobacterium genavense infection mimicking TAFRO syndrome

フルテキストURL	JIC_26_10_1095_1099.pdf
著者	Oka, Kosuke\| Yamane, Mai\| Yokota, Yuya\| Yasuda, Miho\| Hasegawa, Kou\| Fujimori, Takumi\| Iio, Koji\| Hagiya, Hideharu\| Otsuka, Fumio\|
キーワード	Disseminated infection Immunoproliferative disorders Non-tuberculous mycobacteria Osteomyelitis TAFRO syndrome
備考	This fulltext is available in July 2021.\|
発行日	2020-10
出版物タイトル	Journal of Infection and Chemotherapy
巻	26巻
号	10号
出版者	Elsevier
開始ページ	1095
終了ページ	1099
ISSN	1341-321X
NCID	AA11057978
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	32684386
DOI	10.1016/j.jiac.2020.06.020
Web of Science KeyUT	000561076200017
関連URL	isVersionOf https://doi.org/10.1016/j.jiac.2020.06.020

BATTLE: Genetically Engineered Strategies for Split-Tunable Allocation of Multiple Transgenes in the Nervous System

フルテキストURL	fulltext.pdf
著者	Kohara, Keigo\| Inoue, Akitoshi\| Nakano, Yousuke\| Hirai, Hirokazu\| Kobayashi, Takuya\| Maruyama, Masato\| Baba, Ryosuke\| Kawashima, Chiho\|
発行日	2020-06-26
出版物タイトル	iScience
巻	23巻
号	6号
出版者	Cell Press
開始ページ	101248
ISSN	25890042
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Author(s).
論文のバージョン	publisher
DOI	10.1016/j.isci.2020.101248
関連URL	isVersionOf

High body mass index is a risk factor for unfavorable clinical outcomes after medial meniscus posterior root repair in well-aligned knees

フルテキストURL	fulltext20210607-5.pdf figure20210607-5.pdf table20210607-5.pdf
著者	Zhang, Ximing\| Furumatsu, Takayuki\| Okazaki, Yuki\| Hiranaka, Takaaki\| Kodama, Yuya\| Xue, Haowei\| Okazaki, Yoshiki\| Ozaki, Toshifumi\|
備考	This is an Accepted Manuscript of an article published by Elsevier This fulltext is available in July 2021.\|
発行日	2020-07-04
出版物タイトル	Journal of Orthopaedic Science
巻	26巻
号	3号
出版者	Elsevier
開始ページ	430
終了ページ	434
ISSN	09492658
NCID	AA11052566
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
論文のバージョン	author
PubMed ID	32636137
DOI	10.1016/j.jos.2020.04.018
Web of Science KeyUT	000651122300020
関連URL	isVersionOf https://doi.org/10.1016/j.jos.2020.04.018

Isolation and identification of the antimicrobial substance included in tempeh using Rhizopus stolonifer NBRC 30816 for fermentation

フルテキストURL	fulltext.pdf
著者	Ito, Masahiro\| Ito, Takashi\| Aoki, Hideyuki\| Nishioka, Koshi\| Shiokawa, Tsugumi\| Tada, Hiroko\| Takeuchi, Yuki\| Takeyasu, Nobuyuki\| Yamamoto, Tadashi\| Takashiba, Shogo\|
キーワード	Fermented soybean food Oral infection Antibacterial Linoleic acid
発行日	2020-07-16
出版物タイトル	International Journal of Food Microbiology
巻	325巻
出版者	Elsevier
開始ページ	108645
ISSN	0168-1605
NCID	AA10455760
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Authors
論文のバージョン	publisher
PubMed ID	32353648
DOI	10.1016/j.ijfoodmicro.2020.108645
Web of Science KeyUT	000537561000010
関連URL	isVresionOf https://doi.org/10.1016/j.ijfoodmicro.2020.108645

Exposure to particulate matter (PM2.5) and prevalence of diabetes mellitus in Indonesia

フルテキストURL	fulltext.pdf
著者	Suryadhi, Made Ayu Hitapretiwi\| Suryadhi, Putu Ayu Rhamani\| Abudureyimu, Kawuli\| Ruma, I Made Winarsa\| Calliope, Akintije Simba\| Wirawan, Dewa Nyoman\| Yorifuji, Takashi\|
キーワード	Air pollution Environmental epidemiology nvironmental health Particulate matter Diabetes mellitus Indonesia
発行日	2020-07
出版物タイトル	Environment International
巻	140巻
出版者	Elsevier
開始ページ	105603
ISSN	0160-4120
NCID	AA00180393
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Authors.
論文のバージョン	publisher
PubMed ID	32344253
DOI	10.1016/j.envint.2020.105603
Web of Science KeyUT	000544883300001
関連URL	isVersionof https://doi.org/10.1016/j.envint.2020.105603

Identification and visualization of oxidized lipids in atherosclerotic plaques by microscopic imaging mass spectrometry-based metabolomics

フルテキストURL	fulltext.pdf
著者	Shen, Lianhua\| Yamamoto, Takushi\| Tan, Xian Wen\| Ogata, Koretsugu\| Ando, Eiji\| Ozeki, Eiichi\| Matsuura, Eiji\|
キーワード	Atherosclerosis Low-density lipoprotein (LDL) Oxidized LDL (oxLDL) Oxidized lipids; Imaging mass microscopy (iMScope) Mass spectroscopy (MS)
発行日	2020-08-28
出版物タイトル	Atherosclerosis
巻	311巻
出版者	Elsevier
開始ページ	1
終了ページ	12
ISSN	00219150
NCID	AA00553457
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	32911376
DOI	10.1016/j.atherosclerosis.2020.08.001
関連URL	isVersionOf https://doi.org/10.1016/j.atherosclerosis.2020.08.001

Learning curve of kidney transplantation in a high-volume center: A Cohort study of 1466 consecutive recipients

フルテキストURL	fulltext.pdf
著者	Takagi, Kosei\| Outmani, Loubna\| Kimenai, Hendrikus J.A.N.\| Terkivatan, Turkan\| Tran, Khe T.C.\| Ijzermans, Jan N.M.\| Minnee, Robert C.\|
キーワード	Kidney transplantation Surgeon volume Outcome Cumulative sum analysis Learning curve
発行日	2020-08
出版物タイトル	International Journal of Surgery
巻	80巻
出版者	Elsevier
開始ページ	129
終了ページ	134
ISSN	1743-9191
NCID	AA12063080
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Author(s).
論文のバージョン	publisher
PubMed ID	32659389
DOI	10.1016/j.ijsu.2020.06.047
Web of Science KeyUT	000561153700036
関連URL	isVersionOf https://doi.org/10.1016/j.ijsu.2020.06.047

Overcoming epithelial-mesenchymal transition-mediated drug resistance with monensin-based combined therapy in non-small cell lung cancer

フルテキストURL	fulltext.pdf figure1.tif figure2.tif figure3.tif spfigure1.tif spfigure2.tif SupTable1.xlsx
著者	Ochi, Kosuke\| Suzawa, Ken\| Tomida, Shuta\| Shien, Kazuhiko\| Takano, Jui\| Miyauchi, Shunsaku\| Takeda, Tatsuaki\| Miura, Akihiro\| Araki, Kota\| Nakata, Kentaro\| Yamamoto, Hiromasa\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Shien, Tadahiko\| Yamane, Masaomi\| Azuma, Kazuo\| Okamoto, Yoshiharu\| Toyooka, Shinichi\|
キーワード	Monensin Epithelial-mesenchymal transition Non-small cell lung cancer Drug repositioning Drug resistance
備考	This fulltext is available in Jul. 2021.\|
発行日	2020-08-27
出版物タイトル	Biochemical and Biophysical Research Communications
巻	529巻
号	3号
出版者	Academic Press
開始ページ	760
終了ページ	765
ISSN	0006-291X
NCID	AA00564395
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	32736704
DOI	10.1016/j.bbrc.2020.06.077
Web of Science KeyUT	000555780500037
関連URL	iaVersionOf https://doi.org/10.1016/j.bbrc.2020.06.077

Cytotoxic Effects of Alcohol Extracts from a Plastic Wrap (Polyvinylidene Chloride) on Human Cultured Liver Cells and Mouse Primary Cultured Liver Cells

JaLCDOI	10.18926/AMO/60371
フルテキストURL	74_4_327.pdf
著者	Yamamoto, Ken-ichi\| Kagawa, Hiroko\| Arimoto, Sakae\| Tan, Xian Wen\| Yasui, Kento\| Oshiki, Toshiyuki\| Sakaguchi, Masakiyo\|
抄録	An increasing accumulation of microplastics and further degraded nanoplastics in our environment is suspected to have harmful effects on humans and animals. To clarify this problem, we tested the cytotoxicity of two types of plastic wrap on human cultured liver cells and mouse primary cultured liver cells. Alcohol extracts from plastic wrap, i.e., polyvinylidene chloride (PVDC), showed cytotoxic effects on the cells. Alcohol extracts of polyethylene (PE) wrap were not toxic. The commercially available PVDC wrap consists of vinylidene chloride, epoxidized soybean oil, epoxidized linseed oil as a stiffener and stabilizer; we sought to identify which component(s) are toxic. The epoxidized soybean oil and epoxidized linseed oil exerted strong cytotoxicity, but the plastic raw material itself, vinylidene chloride, did not. Our findings indicate that plastic wraps should be used with caution in order to prevent health risks.
キーワード	plastic wrap plasticizer, cytotoxicity, liver cells in vitro
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	327
終了ページ	334
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843764
Web of Science KeyUT	000562508700008
NAID	120006880210

Immobility-reducing Effects of Ketamine during the Forced Swim Test on 5-HT1A Receptor Activity in the Medial Prefrontal Cortex in an Intractable Depression Model

JaLCDOI	10.18926/AMO/60368
フルテキストURL	74_4_301.pdf
著者	Takahashi, Kei\| Kitamura, Yoshihisa\| Ushio, Soichiro\| Sendo, Toshiaki\|
抄録	Ketamine has been clinically proven to ameliorate depression, including treatment-resistant depression. The detailed mechanism of action of ketamine in treatment-resistant depression remains unclear. We examined the effects of ketamine on the immobility times of adrenocorticotropic hormone (ACTH)-treated rats during the forced swim test, and we explored the mechanism by which ketamine acts in this model. We investigated the neuroanatomical site of action by microinjecting ketamine into the medial prefrontal cortex of rats. A significant reduction of the rats’ immobility during the forced swim test was observed after the intraperitoneal injection of ketamine in both saline- and ACTH-treated rats. The microinjection of ketamine into the medial prefrontal cortex also decreased immobility during the forced swim test in both saline- and ACTH-treated rats. The immobility-decreasing effect of intraperitoneally injected ketamine was blocked by administering WAY100635, a 5-HT1A receptor antagonist, into the medial prefrontal cortex. These findings contribute to the evidence that ketamine can be useful against treatment-resistant depressive conditions. The immobility-reducing effects of ketamine might be mediated by 5-HT1A receptor activity in the medial prefrontal cortex.
キーワード	ketamine adrenocorticotropic hormone forced swim test medial prefrontal cortex 5-HT1A receptor
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	301
終了ページ	306
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843761
Web of Science KeyUT	000562508700005
NAID	120006880207

Preoperative Use of Alpha-1 Receptor Blockers in Male Patients Undergoing Extracorporeal Shock Wave Lithotripsy for a Ureteral Calculus

JaLCDOI	10.18926/AMO/60367
フルテキストURL	74_4_293.pdf
著者	Yoshioka, Takashi\| Omae, Kenji\| Kawada, Tatsushi\| Inoue, Yosuke\| Sugimoto, Morito\| Oeda, Tadashi\| Uehara, Shinya\| Araki, Motoo\| Fukuhara, Shunichi\|
抄録	In this retrospective single-center cohort study, we investigated the impact of preoperative use of an alpha-1 adrenergic receptor (AR) blocker on the outcome of single-session extracorporeal shock wave lithotripsy (SWL) in 193 male patients who underwent SWL for a single ureteral calculus between 2006 and 2016. We reviewed their medical records to obtain the data on the preoperative use of alpha-1 AR blockers. The primary outcome was treatment success after single-session SWL. We performed a multivariable logistic regression analysis adjusting for clinically important confounders to examine the association between preoperative use of alpha-1 AR blockers and the treatment success of SWL. Among the 193 patients, 15 (7.8%) were taking an alpha-1 AR blocker preoperatively. A multivariable analysis showed that preoperative use of an alpha-1 AR blocker was a significant negative predictor for treatment success of SWL (adjusted odds ratio 0.17; 95% confidence intervals, 0.04-0.74). Our findings suggest that the preoperative use of an alpha-1 AR blocker was a negative predictor of treatment success of SWL in male patients with a single ureteral calculus. Clinicians should pay more attention to the preoperative drug use in determining an appropriate stone therapy modality.
キーワード	urolithiasis extracorporeal shockwave therapy adrenergic alpha-1 receptor antagonists
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	293
終了ページ	299
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843760
Web of Science KeyUT	000562508700004
NAID	120006880206

Comparison of Two Different Intensive Care Unit Systems for Severely Ill Children in Japan: Data from the JaRPAC Registry

JaLCDOI	10.18926/AMO/60365
フルテキストURL	74_4_285.pdf
著者	Tsukahara, Kohei\| Naitou, Hiromichi\| Yorifuji, Takashi\| Nosaka, Nobuyuki\| Yamamoto, Hirotsugu\| Osako, Takaaki\| Nakao, Atsunori\| the JaRPAC Study Group\|
抄録	The importance of centralizing treatment services for severely ill children has been well established, but such entralization remains difficult in Japan. We aimed to compare the trauma and illness severity and mortality of children admitted to two common types of ICUs for children. According to the type of management and disposition of the medical provider, we classified ICUs as pediatric ICUs [PICUs] or general ICUs, and analyzed differences in endogenous and exogenous illness settings between them. Overall, 1,333 pediatric patients were included, with 1,143 patients admitted to PICUs and 190 patients to general ICUs. The Pediatric Cerebral Performance Category score (PCPC) at discharge was significantly lower in the PICU group (adjusted OR: 0.45; 95%CI: 0.23-0.88). Death and unfavorable neurological outcomes occurred less often in the PICU group (adjusted OR: 0.29; 95%CI: 0.14-0.60). However, when limited to exogenous illness, PCPC scores (adjusted OR: 0.38; 95%CI: 0.07-1.99) or death/unfavorable outcomes (adjusted OR: 0.72; 95%CI: 0.08-6.34) did not differ between the groups. PCPC deterioration and overall sequelae/death rates were lower in PICUs for children with endogenous illnesses, although the outcomes of exogenous illness were similar between the 2 unit types. Further studies on the necessity of centralization are warranted.
キーワード	kids critical care mortality morbidity centralization
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	285
終了ページ	291
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843759
Web of Science KeyUT	000562508700003
NAID	120006880204

Decreased Serum Antioxidant Marker is Predictive of Early Recurrence in the Same Segment after Radical Ablation for Hepatocellular Carcinoma

JaLCDOI	10.18926/AMO/60364
フルテキストURL	74_4_275.pdf
著者	Muro, Taiko\| Nakamura, Shinichiro\| Takaki, Akinobu\| Onishi, Hideki\| Wada, Nozomu\| Yasunaka, Tetsuya\| Uchida, Daisuke\| Oyama, Atsushi\| Adachi, Takuya\| Shiraha, Hidenori\| Okada, Hiroyuki\|
抄録	Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is a promising method for controlling tumors, although it does not entirely eliminate recurrence. Oxidative stress is associated with the progression of hepatocarcinogenesis, while also acting as an anticancer response. The objective of the present study was to investigate the factors influencing post-RFA outcomes. We recruited 235 newly diagnosed HCC patients who received RFA for single tumors. The patients with recurrence were sub-grouped into early and segmental recurrence groups. The characteristics of the sub-grouped patients were evaluated, including by measuring oxidative stress marker reactive oxygen metabolites and antioxidant marker OXY-adsorbent tests. The factors associated with poor survival were a high Child-Pugh score and early recurrence within 2 years in the same segment. The patients who experienced recurrence within 2 years in the same segment showed a larger tumor diameter than did others. According to a multivariate analysis, the OXY values were also significantly low in these patients. In conclusion, maintaining the antioxidant reservoir function with a high OXY value might be necessary to prevent early recurrence within the RFA-treated segment.
キーワード	oxidative stress hepatocellular carcinoma recurrence, radiofrequency ablation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	275
終了ページ	283
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843758
Web of Science KeyUT	000562508700002
NAID	120006880203

Factors Predicting a Favorable Disease Course Without Anti-TNF Therapy in Crohn’s Disease Patients

JaLCDOI	10.18926/AMO/60363
フルテキストURL	74_4_265.pdf
著者	Inokuchi, Toshihiro\| Hiraoka, Sakiko\| Yasutomi, Eriko\| Oka, Shohei\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Takahar, Masahiro\| Kawano, Seiji\| Harada, Keita\| Okada, Hiroyuki\| Kato, Jun\|
抄録	Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
キーワード	Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-08
巻	74巻
号	4号
出版者	Okayama University Medical School
開始ページ	265
終了ページ	274
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32843757
Web of Science KeyUT	000562508700001
NAID	120006880202

Identification and functional analysis of glutamine transporter inStreptococcus mutans

フルテキストURL	fulltext.pdf
著者	Morikawa, Yuko\| Morimoto, Setsuyo\| Yoshida, Eri\| Naka, Shuhei\| Inaba, Hiroaki\| Matsumoto-Nakano, Michiyo\|
キーワード	Streptococcus mutans glutamine transporter biofilm membrane protein glnP
発行日	2020-08-04
出版物タイトル	Journal of Oral Microbiology
巻	12巻
号	1号
出版者	Taylor & Francis
開始ページ	1797320
ISSN	2000-2297
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Author(s).
論文のバージョン	publisher
DOI	10.1080/20002297.2020.1797320
Web of Science KeyUT	000555592200001
関連URL	isVersionOf https://doi.org/10.1080/20002297.2020.1797320

The neutrophil-to-lymphocyte ratio as a novel independent prognostic factor for multiple metastatic lung tumors from various sarcomas

フルテキストURL	fulltext.pdf Tables.pdf Fig1.tif Fig2.tif Supplementary Tables.pdf Supplementary Fig.pdf
著者	Yamamoto, Hiromasa\| Namba, Kei\| Yamamoto, Haruchika\| Toji, Tomohiro\| Soh, Junichi\| Shien, Kazuhiko\| Suzawa, Ken\| Kurosaki, Takeshi\| Otani, Shinji\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Yamane, Masaomi\| Takahashi, Katsuhito\| Kunisada, Toshiyuki\| Oto, Takahiro\| Toyooka, Shinichi\|
キーワード	Metastatic lung tumor Sarcoma Metastasectomy Survival rate Neutrophil-to-lymphocyte ratio (NLR)
備考	This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-020-02093-5. \|
発行日	2020-08-03
出版物タイトル	Surgery Today
出版者	Springer
ISSN	0941-1291
NCID	AA10824685
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	32747982
DOI	10.1007/s00595-020-02093-5
Web of Science KeyUT	000555382600001
関連URL	isVersionOf https://doi.org/10.1007/s00595-020-02093-5