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フルテキストURL O0004444_abstract_review.pdf O0004444_fulltext.pdf
著者 橘 翔子|
発行日 2015-03-25
資料タイプ 学位論文
学位授与番号 乙第4444号
学位授与年月日 2015-03-25
学位・専攻分野 博士(学術)
授与大学 岡山大学
言語 日本語
フルテキストURL O0004441_abstract_review.pdf O0004441_fulltext.pdf
著者 Md Tasyrif bin Abdul Rahman|
発行日 2015-03-25
資料タイプ 学位論文
学位授与番号 乙第4441号
学位授与年月日 2015-03-25
学位・専攻分野 博士(工学)
授与大学 岡山大学
言語 英語
JaLCDOI 10.18926/AMO/53342
フルテキストURL 69_2_123.pdf
著者 Waseda, Koichi| Hagiya, Hideharu| Hanayama, Yoshihisa| Terasaka, Tomohiro| Kimura, Kosuke| Tsuzuki, Takao| Hasegawa, Kou| Nada, Takahiro| Nakamura, Eri| Murakami, Kazutoshi| Kondo, Eisei| Otsuka, Fumio|
抄録 An 81-year-old Japanese male with primary Sjögren syndrome (pSS) developed a low-grade fever and productive cough which were refractory to antibiotic therapy. Based on the high level of eosinophils observed in his bronchial alveolar lavage, he was diagnosed with chronic eosinophilic pneumonia (CEP) and successfully treated by oral prednisolone. Interstitial lung diseases associated with pSS (pSS-ILDs) usually present as nonspecific interstitial pneumonia or usual interstitial pneumonia; therefore, the present case is extremely unique in that the patientʼs condition was complicated with CEP. A diagnosis of advanced gallbladder cancer was made in the patientʼs clinical course, suggesting the advisability of a whole-body workup in cases of pSS, especially in elderly patients.
キーワード bronchial alveolar lavage eosinophilic pneumonia eosinophilia interstitial lung diseases Sjögren syndrome
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 123
終了ページ 127
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899635
Web of Science KeyUT 000353181700008
JaLCDOI 10.18926/AMO/53341
フルテキストURL 69_2_119.pdf
著者 Terasaka, Tomohiro| Hagiya, Hideharu| Kimura, Kosuke| Nada, Takahiro| Nakamura, Eri| Hanayama, Yoshihisa| Sugiyama, Hitoshi| Kobayashi, Yasuyuki| Yanai, Hiroyuki| Otsuka, Fumio|
抄録 We report the case of a 46-year-old hypertensive Japanese female with renal insufficiency related to unilateral renal hypoplasia. The patient was found to have developed paraganglioma in the retroperitoneal space over a 5-year period. Catecholamine-producing tumors are not usually recognized as conditions associated with renal hypoplasia. Our long-term observation of the patient eventually led us to the diagnosis of paraganglioma. In hypertensive patients with chronic kidney disease, not only the renin-angiotensin-aldosterone system but also catecholamine activity may be involved, particularly in the patients whose cases are complicated with unilateral renal hypoplasia.
キーワード catecholamine paraganglioma renal hypoplasia renovascular hypertension secondary hypertension
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 119
終了ページ 122
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899634
Web of Science KeyUT 000353181700007
JaLCDOI 10.18926/AMO/53340
フルテキストURL 69_2_113.pdf
著者 Inada, Ryo| Nagasaka, Takeshi| Toshima, Toshiaki| Mori, Yoshiko| Kondo, Yoshitaka| Kishimoto, Hiroyuki| Hiraki, Takao| Oshiro, Taihei| Kanemitsu, Yukihide| Fujiwara, Toshiyoshi|
抄録 A case of advanced rectal cancer treated by aggressive local and systemic treatment who has survived more than 7 years from initial recurrence is presented. A 55-year-old woman was diagnosed with advanced lower rectal cancer and underwent a low anterior resection with complete removal of all regional lymph nodes and total mesorectal excision. The tumor was diagnosed as a moderately differentiated adenocarcinoma, pStage IIIB (T3, N2a, M0). Twenty-six months after the initial surgery, local recurrence in the pelvis was detected by computed tomography, and total pelvic exenteration with distal sacrectomy (TPES) was performed after systemic chemotherapy with a molecular-targeted drug. Six months after the TPES, multiple lung metastases were detected. Consequently, the patient underwent radiofrequency ablation (RFA) and chemotherapy. The disease has since been controlled for 38 months. As volume control is essential for cancer treatment, it may be important to combine appropriate local therapy with systemic therapy to metastatic or recurrent sites in order to achieve much longer disease control.
キーワード colorectal cancer recurrence total pelvic exenteration radiofrequency ablation systemic chemotherapy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 113
終了ページ 118
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899633
Web of Science KeyUT 000353181700006
JaLCDOI 10.18926/AMO/53339
フルテキストURL 69_2_105.pdf
著者 Sawada, Daijo| Ogawa, Takaaki| Miyake, Minoru| Hasui, Yoshinori| Yamaguchi, Fuminori| Izumori, Ken| Tokuda, Masaaki|
抄録 We examined and compared the inhibitory effects of D-tagatose on the growth, acid production, and water-insoluble glucan synthesis of GS5, a bacterial strain of Streptococcus mutans, with those of xylitol, D-psicose, L-psicose and L-tagatose. GS5 was cultured for 12h in a medium containing 10オ (w/v) of xylitol, D-psicose, L-psicose, D-tagatose or L-tagatose, and the inhibitory effect of GS5 growth was assessed. Each sugar showed different inhibitory effects on GS5. Both D-tagatose and xylitol significantly inhibited the acid production and water-insoluble glucan synthesis of GS5 in the presence of 1オ (w/v) sucrose. However, the inhibitory effect of acid production by D-tagatose was significantly stronger than that of xylitol in presence of sucrose.
キーワード Streptococcus mutans D-tagatose xylitol acid production water-insoluble glucan
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 105
終了ページ 111
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899632
Web of Science KeyUT 000353181700005
JaLCDOI 10.18926/AMO/53338
フルテキストURL 69_2_95.pdf
著者 Lee, Mi Geum| Lee, Dong Kyu| Huh, Billy K.| Choi, Sang Sik| Kim, Hee Zoo| Lim, Byung Gun| Kim, Hong Soon| Choi, Yun Suk| Hur, Won Seok| Lee, Mi Kyoung|
抄録 Resiniferatoxin (RTX) is an ultrapotent synthetic TRPV1 (transient receptor potential vanilloid subtype 1) agonist with significant initial transient hyperalgesia followed by a prolonged analgesic effect in response to thermal stimulus. Using a rat model of neuropathic pain, we evaluated the effect of pretreatment with clonidine-which has been shown to relieve intradermal capsaicin-induced hyperalgesia-on the initial hyperalgesic response and the thermal analgesic property of RTX. Thirty-six male rats were divided into 6 treatment groups (n=6 each):RTX 500ng, RTX 1μg, clonidine 20μg (Cl), Cl+RTX 500ng, Cl+RTX 1μg, or normal saline 20μL (control). We evaluated the short-term (180min) and long-term (20 days) analgesic effects of RTX after thermal stimulation and mechanical stimulation. RTX had significant initial transient hyperalgesia followed by a prolonged analgesic effect in response to the thermal stimulus, but the RTX 500ng and RTX 1μg groups showed no initial short-term thermal hyperalgesic responses when pretreated with clonidine. The Cl+RTX 1μg ratsʼ behavior scores indicated that they were more calm and comfortable compared to the RTX 1μg rats. Even though we cannot precisely confirm that pretreatment with clonidine potentiates or adds to the analgesic effect of RTX, clonidine pretreatment with epidural RTX eliminated the initial RTX-associated hyperalgesic response and systemic toxicity in this neuropathic pain rat model.
キーワード clonidine epidural administration resiniferatoxin spinal nerve ligation rat model thermal hyperalgesia
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 95
終了ページ 103
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899631
Web of Science KeyUT 000353181700004
JaLCDOI 10.18926/AMO/53337
フルテキストURL 69_2_87.pdf
著者 Murayama, Hidehiko| Nakata, Yusei| Kanazawa, Akane| Watanabe, Hirokazu| Shigemitsu, Yusuke| Iwasaki, Yuka| Tokorodani, Chiho| Miyazawa, Mari| Nishiuchi, Ritsuo| Kikkawa, Kiyoshi|
抄録 Ventriculoperitoneal shunts (VPSs) are used for the treatment of hydrocephalus. Here we analyzed the outcomes of VPS placements in 24 infants to determine the risk factors for shunt failure. The infants had undergone the initial VPS operation in our hospital between March 2005 and December 2013. They were observed until the end of January 2014. We obtained Kaplan-Meier curves and performed a multivariate Cox regression analysis of shunt failure. Of the 24 cases, the median (range) values for gestational age, birth weight, and birth head circumference (HC) were 37 (27-39) wks, 2,736 (686-3,788) g, and 35.3 (23.0-45.3) cm, respectively. The total number of shunt procedures was 45. Shunt failure rates were 0.51/shunt and 0.0053/shunt/year. Shunt infection rates were 0.13/shunt and 0.0014/shunt/year. The Kaplan-Meier analysis revealed an increased risk for shunt failure in infants <1 month old or in the HC >90オtile. The Cox regression analysis yielded hazard ratios (HRs) of 2.93 (95オ confidence interval (CI), 0.96-10.95, p=0.059) for age <1 month, and 4.46 (95オCI:1.20-28.91,p=0.023) for the HC >90オtile. The multivariate Cox regression analysis showed adjusted HRs of 17.56 (95オCI:2.69-202.8, p=0.001) for age <1 month, and 2.95 (95オCI:0.52-24.84, p=0.228) for the HC >90オtile. Our findings thus revealed that the risk factors for shunt failure in infants include age <1 month at the initial VPS placement.
キーワード head circumference shunt failure shunt infection ventriculoperitoneal shunt
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 87
終了ページ 93
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899630
Web of Science KeyUT 000353181700003
JaLCDOI 10.18926/AMO/53336
フルテキストURL 69_2_79.pdf
著者 Ichimura, Mika| Sasaki, Shinsuke| Mori, Masaharu| Ogino, Tetsuya|
抄録 This paper investigated whether tapping on the median cubital vein or massaging the forearm was more effective in obtaining better venous palpation for venipuncture. Forty healthy volunteers in their twenties were subjected to tapping (10 times in 5 sec) or massage (10 strokes in 20 sec from the wrist to the cubital fossa) under tourniquet inflation on the upper arm. Venous palpation was assessed using the venous palpation score (0-6, with 0 being impalpable). Three venous factors―venous depth, cross-sectional area, and elevation―were also measured using ultrasonography. The venous palpation score increased significantly by tapping but not by massage. Moreover, all 3 venous measurements changed significantly by tapping, while only the depth decreased significantly by massage. The three venous measurements correlated significantly with the venous palpation score, indicating that they are useful objective indicators for evaluating vasodilation. We suggest that tapping is an effective vasodilation technique.
キーワード massage tapping vasodilation venipuncture venous palpation
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 79
終了ページ 85
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899629
Web of Science KeyUT 000353181700002
JaLCDOI 10.18926/AMO/53335
フルテキストURL 69_2_71.pdf
著者 Hiramoto, Hiroki| Dansako, Hiromichi| Takeda, Midori| Satoh, Shinya| Wakita, Takaji| Ikeda, Masanori| Kato, Nobuyuki|
抄録 Persistent infection with hepatitis C virus (HCV) often causes chronic hepatitis, and then shows a high rate of progression to liver cirrhosis and hepatocellular carcinoma. To clarify the mechanism of the persistent HCV infection is considered to be important for the discovery of new target(s) for the development of anti-HCV strategies. In the present study, we found that the expression level of annexin A1 (ANXA1) in human hepatoma cell line Li23-derived D7 cells was remarkably lower than that in parental Li23 cells, whereas the susceptibility of D7 cells to HCV infection was much higher than that of Li23 cells. Therefore, we hypothesized that ANXA1 negatively regulates persistent HCV infection through the inhibition of viral RNA replication. The results revealed that HCV production was significantly inhibited without a concomitant reduction in the amount of lipid droplets in the D7 cells stably expressing exogenous ANXA1. Further, we demonstrated that ANXA1 negatively regulated the step of viral RNA replication rather than that of viral entry in human hepatocytes. These results suggest that ANXA1 would be a novel target for the development of anti-HCV strategies.
キーワード HCV annexin A1 Li23 cell line Li23-derived D7 cells HCV-JFH-1
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 71
終了ページ 78
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899628
Web of Science KeyUT 000353181700001
著者 岡山大学大学院法務研究科|
発行日 2015-03
出版物タイトル 臨床法務研究
14巻
資料タイプ その他
フルテキストURL hss_039_contents_eng.pdf
著者 岡山大学大学院社会文化科学研究科|
出版物タイトル 岡山大学大学院社会文化科学研究科紀要
発行日 2015-03-26
39巻
ISSN 1881-1671
言語 英語
著作権者 Copyright © 2015 岡山大学大学院社会文化科学研究科
論文のバージョン publisher
JaLCDOI 10.18926/53320
タイトル(別表記) A Bibliographic Study of the Transition of the Chinese Characters Representing 'Jomon'
フルテキストURL hss_039_213_232.pdf
著者 里見 絢子|
出版物タイトル 岡山大学大学院社会文化科学研究科紀要
発行日 2015-03-26
39巻
開始ページ 213
終了ページ 232
ISSN 1881-1671
言語 日本語
著作権者 Copyright © 2015 岡山大学大学院社会文化科学研究科
論文のバージョン publisher
NAID 120005593537
JaLCDOI 10.18926/53319
タイトル(別表記) On the Assertive Function in Japanese and English Suggestions
フルテキストURL hss_039_195_211.pdf
著者 鷲野 亜紀|
出版物タイトル 岡山大学大学院社会文化科学研究科紀要
発行日 2015-03-26
39巻
開始ページ 195
終了ページ 211
ISSN 1881-1671
言語 日本語
著作権者 Copyright © 2015 岡山大学大学院社会文化科学研究科
論文のバージョン publisher
NAID 120005593536
JaLCDOI 10.18926/53318
タイトル(別表記) Usage Conditions of the Continuative Form of Verb by Japanese Native Speakers and Japanese Language Learners-Analysis of the ‘YNU Corpus'-
フルテキストURL hss_039_179_194.pdf
著者 宮崎 聡子|
出版物タイトル 岡山大学大学院社会文化科学研究科紀要
発行日 2015-03-26
39巻
開始ページ 179
終了ページ 194
ISSN 1881-1671
言語 日本語
著作権者 Copyright © 2015 岡山大学大学院社会文化科学研究科
論文のバージョン publisher
NAID 120005593535
JaLCDOI 10.18926/53315
タイトル(別表記) Social Life Difficulties of Muslim Students in Japan
フルテキストURL hss_039_137_151.pdf
著者 中野 祥子| 奥西 有理| 田中 共子|
出版物タイトル 岡山大学大学院社会文化科学研究科紀要
発行日 2015-03-26
39巻
開始ページ 137
終了ページ 151
ISSN 1881-1671
言語 日本語
著作権者 Copyright © 2015 岡山大学大学院社会文化科学研究科
論文のバージョン publisher
NAID 120005593532
フルテキストURL hss_039_contents.pdf
著者 岡山大学大学院社会文化科学研究科|
出版物タイトル 岡山大学大学院社会文化科学研究科紀要
発行日 2015-03-26
39巻
ISSN 1881-1671
言語 日本語
著作権者 Copyright © 2015 岡山大学大学院社会文化科学研究科
論文のバージョン publisher
著者 中谷 ひとみ|
発行日 2015-03-26
出版物タイトル 文化共生学研究
14巻
資料タイプ 紀要論文
JaLCDOI 10.18926/53302
フルテキストURL hara_CASPer15_final_rev2.pdf
著者 Hara, Sunao| Abe, Masanobu| Sonehara, Noboru|
備考 © © 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. The article has been accepted for publication.
Published in:Pervasive Computing and Communication Workshops (PerCom Workshops), 2015 IEEE International Conference on;
Date of Conference:23-27 March 2015;
Page(s):390 - 395;
Conference Location : St. Louis, MO, USA;
Publisher:IEEE;
Publisher URL:http://dx.doi.org/10.1109/PERCOMW.2015.7134069 ;
© Copyright 2015 IEEE - All rights reserved.|
発行日 2015-03
出版物タイトル Proceedings of 2015 IEEE International Conference on Pervasive Computing and Communication Workshops (PerCom Workshops)
出版者 IEEE
開始ページ 390
終了ページ 395
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
DOI 10.1109/PERCOMW.2015.7134069
タイトル(別表記) The 50th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery
フルテキストURL 127_69.pdf
著者 佐野 俊二|
出版物タイトル 岡山医学会雑誌
発行日 2015-04-01
127巻
1号
開始ページ 69
終了ページ 72
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.69
NAID 130005068343