検索結果 229 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Akhtar, Muhammad Shahbaz| Aslam, Sohaib| Ditta, Allah| Albalawi, Bedur Faleh A.| Oki, Yoko| Nakashima, Yoshitaka| |
| キーワード | Azolla biomass bioconcentration factor Cu removal efficiency Cu toxicity translocation factor |
| 発行日 | 2022-12-28 |
| 出版物タイトル | Sustainability |
| 巻 | 15巻 |
| 号 | 1号 |
| 出版者 | MDPI |
| 開始ページ | 497 |
| ISSN | 2071-1050 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/su15010497 |
| Web of Science KeyUT | 000909376900001 |
| 関連URL | isVersionOf https://doi.org/10.3390/su15010497 |
| フルテキストURL | fulltext20221122-4.pdf |
|---|---|
| 著者 | Yamaguchi, Kizashi| Shoji, Mitsuo| Isobe, Hiroshi| Kawakami, Takashi| Miyagawa, Koichi| Suga, Michihiro| Akita, Fusamichi| Shen, Jian-Ren| |
| キーワード | Water oxidation Oxygen evolution Photosystem II HR XRD SFX XFEL QM/MM calculation DLPNO CCSD(T-0) computations, Oxyl radical character |
| 備考 | (C) 2022 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.ccr.2022.214742| This full-text file will be available in Aug. 2024.| |
| 発行日 | 2022-11 |
| 出版物タイトル | Coordination Chemistry Reviews |
| 巻 | 471巻 |
| 出版者 | Elsevier BV |
| 開始ページ | 214742 |
| ISSN | 0010-8545 |
| NCID | AA00619249 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Elsevier B.V. |
| 論文のバージョン | author |
| DOI | 10.1016/j.ccr.2022.214742 |
| Web of Science KeyUT | 000879286600003 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.ccr.2022.214742 |
| JaLCDOI | 10.18926/AMO/64117 |
|---|---|
| フルテキストURL | 76_6_673.pdf |
| 著者 | Okazawa-Sakai, Mika| Yamamoto, Yasuko| Futagawa, Mashu| Okamura, Miki| Miyawaki, Satoko| Nishina, Tomohiro| Takehara, Kazuhiro| Kozuki, Toshiyuki| Tomida, Shuta| Hyodo, Ichinosuke| Ohsumi, Shozo| Hirasawa, Akira| |
| 抄録 | Patients found to have presumed germline pathogenic variants (PGPVs) during comprehensive genomic profiling (CGP) require genetic counseling (GC) referrals. We retrospectively investigated the outcomes of patients with PGPVs. Among 159 patients who underwent CGP, we recommended GC for the 16 patients with PGPVs (3 with [FG group] and 13 without [G Group] a family/personal history of hereditary cancer) as well as for the 8 patients with no PGPVs, but a history (F group); 2 (67%), 5 (38%), and 3 (38%) patients received GC in the FG, G, and F groups, respectively. Germline testing results were positive in 1 and 2 patients of the FG and G groups, respectively. Among the patients recommended for GC, 58% did not receive GC due to lack of interest, poor performance status, or death. CGP contributes to the identification of germline variants in patients without a history of hereditary cancer. However, the proportion of patients who undergo GC should be improved. |
| キーワード | comprehensive genomic profiling hereditary cancer germline findings presumed germline pathogenic variant(s) genetic counseling |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 673 |
| 終了ページ | 678 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549769 |
| Web of Science KeyUT | 000905195100007 |
| JaLCDOI | 10.18926/AMO/64036 |
|---|---|
| フルテキストURL | 76_5_547.pdf |
| 著者 | Kagawa, Hidetoshi| Yamanaka, Ryutaro| Hiromasa, Tsutomu| |
| 抄録 | This observational study aimed to clarify the long-term results of the combination of mizoribine (MZB), tacrolimus (TAC) and prednisolone as first-line therapy for lupus nephritis (LN). This was our institution’s standard therapy between 2009 and 2015, when we saw 36 patients with LN. When a patient thus treated achieved SLEDAI remission (= 0) and/or the prednisolone dose could be tapered to 5 mg/day, either MZB or TAC was stopped, and the other was continued for maintenance therapy. If treatment failure or relapse occurred, second-line therapy was introduced. At years 1 and 5, overall complete renal response and SLEDAI remission were 94% and 88%, and 50% and 62%, respectively. Excluding 2 cases lost to follow-up, medications after 5 years were as follows: 20 (59%) were stable on 1 drug (MZB or TAC), 11 (32%) required continuation of both drugs (MZB + TAC), and 3 (9%) required second-line therapy. The 5-year retention rate was 91% (non-secondline), with 0% of relapse in this group. Our first-line combination strategy showed high remission rates in the induction phase, and subsequent maintenance therapy demonstrated good outcomes for up to 5 years. Research that fine-tunes the order of therapeutic agents and institutes appropriate treatment goals may further improve long-term outcomes for patients with LN. |
| キーワード | combination therapy first-line therapy lupus nephritis mizoribine tacrolimus |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 547 |
| 終了ページ | 555 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352802 |
| Web of Science KeyUT | 000884907100008 |
| JaLCDOI | 10.18926/AMO/63906 |
|---|---|
| フルテキストURL | 76_4_465.pdf |
| 著者 | Bekku, Kensuke| Tsugawa, Takuji| Tsuboi, Kazuma| Noda, Gaku| Inoue, Yousuke| Murao, Wataru| Ebara, Shin| |
| 抄録 | We aimed to identify the role of first-line monotherapy with vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKI) in patients with metastatic RCC. Eligible patients were categorized into three groups (favorable, intermediate, and poor risk) according to the International Metastatic RCC Database Consortium risk criteria. Overall survival (OS) was the primary endpoint. Survival was compared using the log-rank test. A total of 108 patients were retrospectively analyzed. The numbers of patients in the favorable-, intermediate-, and poor-risk groups were 32 (30%), 66 (61%), and 10 (9%), repestively. The median OS values in the entire cohort was 36 months (95% confidence interval [CI] 29-53). The median OS in the favorable, intermediate, and poor risk groups were 94 months (95% CI: 43-Not reached), 30 months (95% CI: 20-38), and 8 months (95% CI: 0-Not reached), respectively (p<0.05). Prior nephrectomy, clear cell histology, clinical T stage ≤2, no metastasis at the time of diagnosis, nivolumab beyond first-line therapy, and objective response to VEGFR-TKIs were factors significantly prolonging OS on univariate analysis. VEGFR-TKI monotherapy as first-line therapy was an effective treatment option for patients with metastatic clear cell RCC with favorable risk. |
| キーワード | metastatic renal cell carcinoma molecular-targeted therapy immuno-checkpoint inhibitor real-world setting |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-08 |
| 巻 | 76巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 465 |
| 終了ページ | 472 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36123162 |
| JaLCDOI | 10.18926/AMO/63887 |
|---|---|
| フルテキストURL | 76_4_359.pdf |
| 著者 | Hiramatsu-Asano, Sumie| Wada, Jun| |
| 抄録 | Systemic lupus erythematosus (SLE) is a potentially fatal systemic autoimmune disease, and its etiology involves both genetic and environmental factors such as sex hormone imbalance, genetic predisposition, epigenetic regulation, and immunological factors. Dysregulation of microRNA (miRNA) is suggested to be one of the epigenetic factors in SLE. miRNA is a 22-nucleotide single-stranded noncoding RNA that contributes to post-transcriptional modulation of gene expression. miRNA targeting therapy has been suggested to be useful for the treatment of cancers and other diseases. Gene knockout and miRNA targeting therapy have been demonstrated to improve SLE disease activity in mice. However, these approaches have not yet reached the level of clinical application. miRNA targeting therapy is limited by the fact that each miRNA has multiple targets. In addition, the expression of certain miRNAs may differ among cell tissues within a single SLE patient. This limitation can be overcome by targeted delivery and chemical modifications. In the future, further research into miRNA chemical modifications and delivery systems will help us develop novel therapeutic agents for SLE. |
| キーワード | systemic lupus erythematosus miRNA miRNA targeting therapy |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-08 |
| 巻 | 76巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 359 |
| 終了ページ | 371 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36123150 |
| Web of Science KeyUT | 000882167300002 |
| JaLCDOI | 10.18926/AMO/63718 |
|---|---|
| フルテキストURL | 76_3_247.pdf |
| 著者 | Yoshida, Shohei| Fujii, Nobuharu| Kamoi, Chihiro| Kitamura, Wataru| Fujiwara, Hideaki| Asada, Noboru| Nishimori, Hisakazu| Fujii, Keiko| Matsuoka, Ken-ichi| Maeda, Yoshinobu| |
| 抄録 | Vaccine-preventable disease (VPD) infections are more severe in immunocompromised hosts. Vaccination against measles, mumps, rubella, and varicella zoster (VZV) (MMRV) is therefore recommended for hematopoietic stem cell transplantation (HCT) recipients. However, studies on adult HCT recipients with VPD infections are limited. At our institution, we have systematically conducted serological MMRV tests as a part of check-up examinations during long-term follow-up (LTFU) after HCT since 2015. This retrospective study aimed to evaluate changes in the serostatus between before and 2 years after allogeneic HCT. Among 161 patients, the pre-transplant seropositivity was 82.7% for measles, 86.8% for mumps, 84.2% for rubella, and 94.3% for VZV. Among 56 patients who underwent LTFU including serological MMRV tests at 2 years after HCT, the percentages maintaining seroprotective antibody levels for measles, mumps, rubella and VZV were 71.5% (40/56), 51.8% (29/56), 48.2% (27/56), and 60.7% (34/56), respectively. Vaccination was recommended for 22 patients, and 12 were vaccinated. Among the 12 vaccinated patients, rates of seroconversion were examined in 2-6 patients for each of the four viruses. They were 100% (3/3) for measles, 33.3% (1/3) for mumps, 50% (3/6) for rubella, and 0% (0/2) for VZV. Further studies are warranted to clarify the effect of vaccination in adult HCT recipients. |
| キーワード | vaccine-preventable disease vaccination allogeneic hematopoietic stem cell transplantation adult |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 247 |
| 終了ページ | 253 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790354 |
| Web of Science KeyUT | 000823568300003 |
| タイトル（別表記） | Propagation characteristics and method of appropriate management of invasive alien species Iris pseudacorus L. |
|---|---|
| フルテキストURL | srfa_111_021_025.pdf |
| 著者 | 中嶋 佳貴| |
| 抄録 | To establish a proposal for a guiding principle supporting appropriate management of Iris pseudacorus L., which had been used as an important vegetation bank species until the Invasive Alien Species Act, this study investigated propaga-tion characteristics. The seed in which seed coat cracked germinated earlier, and it was shown that their cumulative germination percentage was high even under 30 °C constant conditions. When the fresh weight of the rhizome cut pieces in the spring became greater than 15 g, the individual plant flowering rate increased gradually. Individuals of more than 30 g achieved a flowering rate higher than 76 %. The flow-ering rate was highest for individual plants that had two green leaves, but it became progressively lower for increas-ing numbers of green leaves：non-flowering individuals grew better than flowering individuals. In the 0 cm height scape-cutting treatment, no significant difference was found in the numbers of flowers and fruits the next year. In the 5 cm height top-cutting treatment, the flowers and fruits in the next year were significantly fewer. |
| キーワード | Iris pseudacorus L. invasive alien species propagation characteristics flood tolerance |
| 出版物タイトル | 岡山大学農学部学術報告 |
| 発行日 | 2022-02-01 |
| 巻 | 111巻 |
| 開始ページ | 21 |
| 終了ページ | 25 |
| ISSN | 2186-7755 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120007190705 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tamura, Kazuya| Tokuzen-Tai, Masako| Siddiqui, Yasir Dilshad| Tamura-Naito, Hitomi| Nagahara, Yoshiharu| Hatanaka-Takeuchi, Kazu| Yamamoto, Tadashi| Takashiba, Shogo| |
| キーワード | Dog Periodontitis Periodontal pocket surface area Estimation method Periodontology |
| 発行日 | 2022-01-03 |
| 出版物タイトル | BMC Veterinary Research |
| 巻 | 18巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 13 |
| ISSN | 1746-6148 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021. |
| 論文のバージョン | publisher |
| PubMed ID | 34980120 |
| DOI | 10.1186/s12917-021-03116-0 |
| Web of Science KeyUT | 000737982200010 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12917-021-03116-0 |
| フルテキストURL | mjou_064_187_190.pdf |
|---|---|
| 著者 | Puthenpurakal, Tony J. | |
| 抄録 | Let K be a field and consider the standard grading on A = K[X1, ... ,Xd]. Let I, J be monomial ideals in A. Let In(J) = (In : J∞) be the nth symbolic power of I with respect to J. It is easy to see that the function fI J (n) = e0(In(J)/In) is of quasi-polynomial type, say of period g and degree c. For n ≫ 0 say fIJ (n) = ac(n)nc + ac−1(n)nc−1 + lower terms, where for i = 0, ... , c, ai : N → Q are periodic functions of period g and ac ≠0. In [4, 2.4] we (together with Herzog and Verma) proved that dim In(J)/In is constant for n ≫ 0 and ac(−) is a constant. In this paper we prove that if I is generated by some elements of the same degree and height I ≥ 2 then ac−1(−) is also a constant. |
| キーワード | quasi-polynomials monomial ideals symbolic powers |
| 発行日 | 2022-01 |
| 出版物タイトル | Mathematical Journal of Okayama University |
| 巻 | 64巻 |
| 号 | 1号 |
| 出版者 | Department of Mathematics, Faculty of Science, Okayama University |
| 開始ページ | 187 |
| 終了ページ | 190 |
| ISSN | 0030-1566 |
| NCID | AA00723502 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright ©2022 by the Editorial Board of Mathematical Journal of Okayama University |
| フルテキストURL | fulltext20211118-1.pdf |
|---|---|
| 著者 | Kitaoku, Yoshihito| Fukamizo, Tamo| Kumsaoad, Sawitree| Ubonbal, Prakayfun| Robinson, Robert C.| Suginta, Wipa| |
| 発行日 | 2021-09-30 |
| 出版物タイトル | Journal of Biological Chemistry |
| 巻 | 297巻 |
| 出版者 | Elsevier Inc |
| 開始ページ | 101071 |
| ISSN | 00219258 |
| NCID | AA00251083 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology. |
| 論文のバージョン | publisher |
| PubMed ID | 34400168 |
| DOI | 10.1016/j.jbc.2021.101071 |
| Web of Science KeyUT | 000714635500005 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.jbc.2021.101071 |
| JaLCDOI | 10.18926/AMO/62237 |
|---|---|
| フルテキストURL | 75_3_397.pdf |
| 著者 | Sekito, Takanori| Takamoto, Atsushi| Kobayashi, Yasuyuki| Mitsui, Masao| Watari, Shogo| Kubota, Risa| Sadahira, Takuya| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Sako, Tomoko| Araki, Motoo| Watanabe, Masami| Watanabe, Toyohiko| Shibata, Rei| Ennishi, Daisuke| Nasu, Yasutomo| |
| 抄録 | We report a 62-year-old male with metastatic fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) without fumarate hydratase (FH) mutation (FH-deficient–like RCC). The International Metastatic RCC Database Consortium risk score was intermediate, and immunotherapy with nivolumab and ipilimumab (Ipi/ Nivo) was initiated. Four cycles of Ipi/Nivo and 5 cycles of nivolumab resulted in a complete response of the metastases. Hypophysitis occurred as an immune-related adverse event after four cycles of Ipi/Nivo. The prognosis of patients with FH-deficient RCC is generally poor. Few reports of FH-deficient RCC successfully treated with Ipi/Nivo have been published. Ipi/Nivo can be effective for treating FH-deficient RCC. |
| キーワード | fumarate hydratase fumarate hydratase-deficient renal cell carcinoma renal cell carcinoma ipilimumab nivolumab |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 397 |
| 終了ページ | 402 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176946 |
| Web of Science KeyUT | 000667147700017 |
| NAID | 120007089822 |
| JaLCDOI | 10.18926/AMO/62228 |
|---|---|
| フルテキストURL | 75_3_335.pdf |
| 著者 | Chikuie, Nobuyuki| Hamamoto, Takao| Ueda, Tsutomu| Taruya, Takayuki| Kono, Takashi| Furuie, Hiromi| Ishino, Takashi| Takeno, Sachio| |
| 抄録 | Recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) has a poor prognosis. Although nivolumab is approved in Japan for treating R/MHNSCC, the response rate is low. Therefore, identifying pretreatment prognostic factors is necessary. This study assessed the utility of the neutrophil-to-lymphocyte ratio (NLR) and Glasgow Prognostic Score (GPS) as biomarkers of response to nivolumab. We retrospectively collected the data of 56 R/MHNSCC patients treated with nivolumab between May 2017 and December 2019. The Kaplan–Meier method and log-rank test were used to estimate overall survival (OS) and progression-free survival (PFS), and multivariate Cox hazard regression analysis was used to identify independent predictors of survival. Patients with a low pretreatment NLR had prolonged OS, and patients with a low pretreatment GPS had increased OS and PFS. A performance score (PS) of 0-1, development of immune-related adverse events, and GPS of 0-1 were significantly associated with OS in multivariate analysis. In summary, baseline pretreatment NLR and GPS are independently associated with OS in R/MHNSCC patients treated with nivolumab. Administration of nivolumab while maintaining the PS reflects a immune status of the host and leads to a good OS. |
| キーワード | neutrophil-to-lymphocyte ratio nivolumab Glasgow Prognostic Score recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 335 |
| 終了ページ | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176937 |
| Web of Science KeyUT | 000667147700008 |
| NAID | 120007089825 |
| JaLCDOI | 10.18926/AMO/61881 |
|---|---|
| フルテキストURL | 75_2_147.pdf |
| 著者 | Xue, Haowei | Furumatsu, Takayuki| Okazaki, Yuki | Hiranaka, Takaaki | Kintaka, Keisuke | Fujii, Masataka | Zhang, Ximing| Ozaki, Toshifumi| |
| 抄録 | Medial meniscus posterior root tears (MMPRTs) have recently attracted considerable interest in orthopedics. To date, no in vivo human study has investigated suture translation changes in repaired MMPRTs with different degrees of knee flexion. This study examined suture translation at various degrees of knee flexion in 30 patients undergoing medial meniscus posterior root repair using the modified Mason-Allen suture technique between August 2016 and September 2017. Intraoperatively, sutures were provisionally fixed to an isometric positioner at the tibial site of the desired meniscal attachment, and the suture translation was measured at 0°, 30°, 60°, and 90° of knee flexion. The results showed significant increases in mean suture translation at the knee flexion positions from 0° to 30°, 30° to 60°, and 60° to 90° (p<0.01 for all). Our findings indicate that surgeons should carefully assess the degree of knee flexion at the moment when the meniscus is refixed by surgical sutures. |
| キーワード | medial meniscus posterior root tear suture translation knee flexion arthroscopic repair |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 147 |
| 終了ページ | 152 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953421 |
| NAID | 120007029902 |
| JaLCDOI | 10.18926/AMO/61878 |
|---|---|
| フルテキストURL | 75_2_125.pdf |
| 著者 | Kijima, Yasufumi| Kondo, Naoki| Okumura, Go| Endo, Naoto| |
| 抄録 | Rheumatoid arthritis (RA) affects the hip joints. The microarchitecture of the cancellous bone in RA-affected hip joints has been unclear. Here we investigated the bone metabolism changes in the subcapital cancellous bone of destructive hips of RA patients (n=26 patients; 28 hip joints) which were classified by Larsen grade on X-ray into the groups: destructive hip (Des) (Larsen grade IV, n=18) and neck fracture (Fx) (Larsen grade 0 or 1, n=10). The femoral heads of the Des-group showed significantly higher trabecular thickness versus those of the Fx-group (179±30.8 vs. 151±23.5 μm, p=0.02). The Des-group had significantly higher osteoid volume/tissue volume (OV/TV) and osteoid volume/bone volume (OV/BV) ratios than the Fx-group (OV/TV: 0.72±0.70% vs. 0.27±0.32%, p=0.028; OV/BV: 2.96±2.85% vs. 1.24±1.31%, p=0.039). The osteoblast and osteoclast surface areas of the Des-group were remarkably higher than those of the Fx-group (9.80±10.9 vs. 0.15±0.15%, p=0.0005; 0.34±0.48 vs. 0.06±0.06%, p=0.0285, respectively). The T-scores of hip (femoral neck) bone mineral density (BMD) of the Fx-group were significantly lower versus those of the Des-group (−3.1±0.76 vs. −1.6±1.17, p<0.01). Increased osteoid and resorption parameters and higher femoral neck BMD demonstrate a high bone-turnover state in response to destructive changes in the hips of RA patients. |
| キーワード | bone histomorphometry rheumatoid arthritis destructive hip femoral neck fracture bone turnover |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 125 |
| 終了ページ | 131 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953418 |
| NAID | 120007029905 |
| フルテキストURL | fulltext20210428_1.pdf |
|---|---|
| 著者 | Hagiwara, Yuuki| Yoshida, Kenta| Yoneda, Akira| Torimoto, Junji| Yamamoto, Junji| |
| キーワード | Finite element method Inclusions Laser heating Raman spectroscopy |
| 発行日 | 2021-01-05 |
| 出版物タイトル | Chemical Geology |
| 巻 | 559巻 |
| 出版者 | Elsevier |
| 開始ページ | 119928 |
| ISSN | 00092541 |
| NCID | AA0060201X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 The Authors. |
| 論文のバージョン | publisher |
| NAID | 120007029907 |
| DOI | 10.1016/j.chemgeo.2020.119928 |
| Web of Science KeyUT | 000600546500016 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.chemgeo.2020.119928 |
| フルテキストURL | fulltext20210519_1.pdf |
|---|---|
| 著者 | Takagi, Kosei| Kimenai, Hendrikus J.A.N.| Terkivatan, Turkan| Tran, Khe T.C.| Ijzermans, Jan N.M.| Minnee, Robert C.| |
| キーワード | Kidney transplantation Learning curve Hand-assisted laparoscopy Laparoscopy Living donors Nephrectomy Teaching Robotic surgical procedures |
| 発行日 | 2021-02-28 |
| 出版物タイトル | International Journal of Surgery |
| 巻 | 86巻 |
| 出版者 | Elsevier |
| 開始ページ | 7 |
| 終了ページ | 12 |
| ISSN | 17439191 |
| NCID | AA12063080 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 33429077 |
| DOI | 10.1016/j.ijsu.2020.12.011 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.ijsu.2020.12.011 |
| フルテキストURL | fulltext20210525_1.pdf |
|---|---|
| 著者 | Laukhtina, Ekaterina| Abufaraj, Mohammad| Al-Ani, Abdallah| Ali, Mustafa Rami| Mori, Keiichiro| Moschini, Marco| Quhal, Fahad| Sari Motlagh, Reza| Pradere, Benjamin| Schuettfort, Victor M.| Mostafaei, Hadi| Katayama, Satoshi| Grossmann, Nico C.| Fajkovic, Harun| Soria, Francesco| Enikeev, Dmitry| Shariat, Shahrokh F.| |
| キーワード | Non–muscle-invasive bladder cancer Bladder cancer Intermediate risk Intravesical therapy Network meta-analysis |
| 発行日 | 2021-03-21 |
| 出版物タイトル | European Urology Focus |
| 出版者 | Elsevier |
| ISSN | 24054569 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 33762203 |
| NAID | 120007039929 |
| DOI | 10.1016/j.euf.2021.03.016 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.euf.2021.03.016 |
| フルテキストURL | fulltext20210530_1.pdf |
|---|---|
| 著者 | Laukhtina, Ekaterina| Pradere, Benjamin| Mori, Keiichiro| Schuettfort, Victor M.| Quhal, Fahad| Mostafaei, Hadi| Sari Motlangh, Reza| Katayama, Satoshi| Grossmann, Nico C.| Moschini, Marco| Enikeev, Dmitry| Shariat, Shahrokh F.| |
| キーワード | Biomarkers UCB bladder cancer Neoadjuvant systemic therapy NAC systematic review |
| 発行日 | 2021-03-31 |
| 出版物タイトル | Urologic Oncology: Seminars and Original Investigations |
| 巻 | 39巻 |
| 号 | 3号 |
| 出版者 | Elsevier |
| 開始ページ | 180 |
| 終了ページ | 190 |
| ISSN | 10781439 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 33423937 |
| DOI | 10.1016/j.urolonc.2020.12.019 |
| Web of Science KeyUT | 000620260700027 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.urolonc.2020.12.019 |
| フルテキストURL | fulltext20210527_1.pdf |
|---|---|
| 著者 | Bi, Zhuoyue| Zhang, Qian| Fu, Yao| Seno, Akimasa| Wadgaonkar, Priya| Qiu, Yiran| Almutairy, Bandar| Xu, Liping| Zhang, Wenxuan| Thakur, Chitra| Chen, Fei| |
| キーワード | Arsenic NRF2 MDIG Cancer stem cells Carcinogenesis |
| 発行日 | 2021-04-03 |
| 出版物タイトル | Seminars in Cancer Biology |
| 出版者 | Elsevier |
| ISSN | 1044579X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 33823236 |
| DOI | 10.1016/j.semcancer.2021.03.030 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.semcancer.2021.03.030 |