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フルテキストURL APL_111_243106_2017.pdf
著者 Ishikawa, Atsushi| Hara, Shuhei| Tanaka, Takuo| Zhan, Xiang| Tsuruta, Kenji|
備考 This is an Accepted Manuscript of an article published by American Institute of Physics|
発行日 2017-12-11
出版物タイトル Applied Physics Letters
111巻
24号
出版者 American Institute of Physics
開始ページ 243106
ISSN 0003-6951
NCID AA00543431
資料タイプ 学術雑誌論文
言語 日本語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
DOI 10.1063/1.5004703
Web of Science KeyUT 000418098900036
関連URL isVersionOf https://doi.org/10.1063/1.5004703
フルテキストURL PhysRevB_95_085109.pdf
著者 Wakita, Takanori| Terashima, Kensei| Hamada, Takahiro| Fujiwara, Hirokazu| Minohara, Makoto| Kobayashi, Masaki| Horiba, Koji| Kumigashira, Hiroshi| Kutluk, Galif| Nagao, Masanori| Watauchi, Satoshi| Tanaka, Isao| Demura, Satoshi| Okazaki, Hiroyuki| Takano, Yoshihiko| Mizuguchi, Yoshikazu| Miura, Osuke| Okada, Kozo| Muraoka, Yuji| Yokoya, Takayoshi|
備考 This is an article published by American Physical Society|
発行日 2017-02
出版物タイトル Physical Review B
95巻
8号
出版者 American Physical Society
開始ページ 085109
ISSN 2469-9950
NCID AA11187113
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevB.95.085109
Web of Science KeyUT 000393501200003
関連URL isVersionOf https://doi.org/10.1103/PhysRevB.95.085109
フルテキストURL J_Cardiology_70_1_23.pdf Fig.pdf
著者 Tachibana, Motomi| Nishii, Nobuhiro| Morimoto, Yoshimasa| Kawada, Satoshi| Miyoshi, Akihito| Sugiyama, Hiroyasu| Nakagawa, Koji| Watanabe, Atsuyuki| Nakamura, Kazufumi| Morita, Hiroshi| Ito, Hiroshi|
キーワード Implantable cardioverter-defibrillator Sudden cardiac death Ventricular arrhythmia
備考 This is an Accepted Manuscript of an article published by Elsevier|
発行日 2017-07
出版物タイトル Journal of Cardiology
70巻
1号
出版者 Japanese College of Cardiology
開始ページ 23
終了ページ 28
ISSN 0914-5087
NCID AN10070473
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 28034575
DOI 10.1016/j.jjcc.2016.11.014
Web of Science KeyUT 000408601100004
関連URL isVersionOf https://doi.org/10.1016/j.jjcc.2016.11.014
フルテキストURL GGI_16_4_440.pdf fig.pdf
著者 Tokuchi, Ryo| Hishikawa, Nozomi| Matsuzono, Kosuke| Takao, Yoshiki| Wakutani, Yosuke| Sato, Kota| Kono, Syoichiro| Ohta, Yasuyuki| Deguchi, Kentaro| Yamashita, Toru| Abe, Koji|
キーワード Alzheimer's disease affective function cognitive function combination therapy galantamine
備考 This is an Accepted Manuscript of an article published by Wiley|
発行日 2016-04
出版物タイトル Geriatrics & Gerontology International
16巻
4号
出版者 Japan Geriatrics Society
開始ページ 440
終了ページ 445
ISSN 1444-1586
NCID AA1155729X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 25952367
DOI 10.1111/ggi.12488
Web of Science KeyUT 000373611800005
関連URL isVersionOf https://doi.org/10.1111/ggi.12488
フルテキストURL PhysRevB_93_094507.pdf
著者 Tanaka, Kenta K.| Ichioka, Masanori| Onari, Seiichiro|
備考 This is an article published by American Physical Society|
発行日 2016-03
出版物タイトル Physical Review B
93巻
9号
出版者 American Physical Society
開始ページ 094507
ISSN 2469-9950
NCID AA11187113
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevB.93.094507
Web of Science KeyUT 000371727300005
関連URL isVersionOf https://doi.org/10.1103/PhysRevB.93.094507
フルテキストURL PhysRevB_95_064512.pdf
著者 Ichioka, Masanori| Kogan, V. G.| Schmalian, J.|
備考 This is an article published by American Physical Society|
発行日 2017-02
出版物タイトル Physical Review B
95巻
6号
出版者 American Physical Society
開始ページ 064512
ISSN 2469-9950
NCID AA11187113
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 ©2017 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevB.95.064512
Web of Science KeyUT 000394657300012
関連URL isVersionOf https://doi.org/10.1103/PhysRevB.95.064512
タイトル(別表記) The 2016 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2016 Sunada Prize)
フルテキストURL 129_155.pdf
著者 藤井 詩子|
出版物タイトル 岡山医学会雑誌
発行日 2017-12-01
129巻
3号
開始ページ 155
終了ページ 157
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.129.155 references https://doi.org/10.1165/rcmb.2016-0015OC
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.155
NAID 40021393805
タイトル(別表記) Übersetzung von Jherings Briefe(1)
フルテキストURL olj_67_2_304.pdf
著者 平田 公夫|
出版物タイトル 岡山大學法學會雜誌
発行日 2017-12-25
67巻
2号
開始ページ 304
終了ページ 279
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 120006375010
タイトル(別表記) Du droit à l’effacement des données à caractère personnel en cas d’atteinte à la vie privée et «le droit à l'oubli numérique», en analysant la décision du 31 janvier 2017 de la Cour Suprême du Japon
フルテキストURL olj_67_2_374.pdf
著者 村田 健介|
出版物タイトル 岡山大學法學會雜誌
発行日 2017-12-25
67巻
2号
開始ページ 374
終了ページ 336
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 120006375006
フルテキストURL olj_67_2_contents.pdf
著者 岡山大学法学会|
出版物タイトル 岡山大學法學會雜誌
発行日 2017-12-25
67巻
2号
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
JaLCDOI 10.18926/AMO/55591
フルテキストURL 71_6_531.pdf
著者 Ooi, Mayu| Yanamoto, Fujio| Sato, Hitoaki| Takao, Yumiko| Okada, Masako| Egi, Moritoki| Mizobuchi, Satoshi|
抄録 Although spinal cord stimulation (SCS) is a useful treatment for chronic intractable pain, the optimal method of stimulation has not yet been established. In this prospective, crossover study, we compared the efficacy of using a constant current (CC) system with that of a constant voltage (CV) system for temporal SCS. Twenty patients were enrolled and divided into two groups. For 10 patients, a CV system was applied on Days 1-5, followed by the use of a CC system on Days 6-10. For the other 10 patients, a CC system was applied for the first five days, followed by a CV system for the subsequent five days. We evaluated the alteration of pain intensity using a visual analogue scale (VAS), the area of stimulation, the stability of effect, and patient satisfaction regarding treatment. The pain scores decreased significantly after the start of the SCS. There was no significant difference in the change in VAS between the two systems. The stimulation method used for temporal SCS did not affect the reduction of pain intensity. Patients felt a wider stimulation area by the CC system compared to the CV system.
キーワード spinal cord stimulation constant current system constant voltage system chronic intractable pain pain score
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-12
71巻
6号
出版者 Okayama University Medical School
開始ページ 531
終了ページ 537
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29276227
JaLCDOI 10.18926/AMO/55588
フルテキストURL 71_6_513.pdf
著者 Sawada, Shigeki| Sugimoto, Ryujiro| Ueno, Tsuyoshi| Yamashita, Motohiro|
抄録 We evaluated the feasibility of maintenance treatment using UFT (a combination of tegafur and uracil) after adjuvant platinum-based chemotherapy in patients with resected lung cancer. A prospective feasibility trial was conducted. Between 2010 and 2014, UFT was administered for 2 years sequentially after platinum-based adjuvant chemotherapy in 24 patients with resected Stage IIA-IIIA non-small cell lung cancer. The safety of UFT and the rate of treatment completion were then evaluated. The prior platinum-based chemotherapy regimens consisted of cisplatin+vinorelbine in 16 patients, carboplatin+paclitaxel in 5 and carboplatin+S-1 in one. During the subsequent UFT administration, a total of 3 patients required a dose reduction because of Grade 1 blood-stained sputum, Grade 2 numbness, and Grade 2 constipation, in one patient each. Eleven patients underwent the planned 2-year UFT administration, but 12 patients could not because of the recurrence of lung cancer in 5 patients, metachronous malignancy in one, and toxicities in 6. The completion rate for UFT administration was 64.7% (11/17). The most common type of toxicity was gastrointestinal toxicities. All of the toxicities were grade 1 or 2, and no severe toxicities were observed. UFT treatment after platinum-based chemotherapy was revealed to be feasible.
キーワード UFT adjuvant chemotherapy lung cancer resection
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-12
71巻
6号
出版者 Okayama University Medical School
開始ページ 513
終了ページ 518
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29276224
JaLCDOI 10.18926/AMO/55587
フルテキストURL 71_6_505.pdf
著者 Honda, Yoshihiro| Takigawa, Nagio| Ichihara, Eiki| Ninomiya, Takashi| Kubo, Toshio| Ochi, Nobuaki| Yasugi, Masayuki| Murakami, Toshi| Yamane, Hiromichi| Tanimoto, Mitsune| Kiura, Katsuyuki|
抄録 (−)-Epigallocatechin-3-gallate (EGCG) has been shown to bind to several receptors including epidermal growth factor receptor (EGFR). EGFR tyrosine kinase inhibitors and anaplastic lymphoma kinase (ALK) inhibitors are effective for non-small cell lung cancers harboring activating EGFR mutations and ALK or c-ros oncogene 1 (ROS1) fusion genes, respectively. We investigated the effects of EGCG on EGFR- or fusion gene-driven lung cancer cells such as PC-9, RPC-9, H1975, H2228 and HCC78. The five cell lines had similar sensitivity to EGCG. Phosphorylated (p)EGFR, pAkt and pErk in PC-9, RPC-9 and H1975 cells were suppressed by EGCG (50 or 100 μM). EGCG also inhibited pALK in H2228, pROS1 in HCC78, and pErk and pAkt in both cell lines. All the xenograft tumors established using the 5 cell lines in EGCG-treated groups were significantly smaller than the tumors in the vehicle-treated groups. The numbers of tumor blood vessels of xenograft tissues in EGCG-treated mice were significantly lower than those in vehicle-treated mice. In conclusion, EGCG may be effective for EGFR-driven lung tumors irrespective of the presence of T790M, and for ALK or ROS1 fusion gene-driven lung tumors.
キーワード epigallocatechin-3-gallate lung cancer EGFR ALK ROS1
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-12
71巻
6号
出版者 Okayama University Medical School
開始ページ 505
終了ページ 512
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29276223
JaLCDOI 10.18926/AMO/55586
フルテキストURL 71_6_493.pdf
著者 Aoe, Michinori| Ueno-Iio, Tomoe| Shibakura, Misako| Shinohata, Ryoko| Usui, Shinichi| Arao, Yujiro| Ikeda, Satoru| Miyahara, Nobuaki| Tanimoto, Mitsune| Kataoka, Mikio|
抄録 Lavender essential oil (Lvn) has anti-inflammatory effects in an ovalbumin-sensitized murine model of asthma, and inhibits inflammatory cell infiltration into the lungs. The anti-inflammatory effects of Lvn on cell adhesion molecules are not clear. Here we evaluated the effects of Lvn and its main constituents, linalyl acetate (LA) and linalool (LO), on the expression of tumor necrosis factor-alpha (TNF-α)-induced cell adhesion molecules in murine brain endothelial bEnd.3 cells and human umbilical vein endothelial cells (HUVECs). The bEnd.3 cells were treated with Lvn, LA, or LO and subsequently stimulated with TNF-α. The mRNA expression levels of cell adhesion molecules were detected using RT-PCR. E-selectin and P-selectin protein and phosphorylated-NF-κB p65 were detected by western blotting. The effects of Lvn on HUVECs were measured by RT-PCR. In bEnd.3 cells, Lvn and LA suppressed TNF-α-induced E-selectin, P-selectin, vascular cell adhesion molecule-1, intercellular adhesion molecule-1, and phosphorylated-NF-κB p65 in the nucleus; LO did not suppress P-selectin or phosphorylated-NF-κB p65. Lvn inhibited TNF-α-induced E-selectin mRNA in HUVECs. These results indicate that Lvn and LA inhibit TNF-α-induced cell adhesion molecules in endothelial cells through the suppression of NF-κB activation. Consequently, Lvn or other essential oils including LA may be useful as alternative anti-inflammatory medicines.
キーワード lavender essential oil linalyl acetate inflammation cell adhesion molecule NF-κB
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-12
71巻
6号
出版者 Okayama University Medical School
開始ページ 493
終了ページ 503
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29276222
JaLCDOI 10.18926/AMO/55585
フルテキストURL 71_6_485.pdf
著者 Okano, Ayaka| Masuhara, Shun| Ota, Sonoka| Motegi, Chie| Takabayashi, Noriko| Ogino, Tetsuya|
抄録 We examined postprandial body positions’ effects on gastrointestinal motility, the autonomic nervous system and subjective comfort, i.e., whether lowering the head after a meal is beneficial for gastrointestinal motility and the prevention of pressure ulcer. We examined 10 healthy subjects and compared 3 body positions: (1) Seated upright. (2) Lying on a bed with the head at 60° and knees up by 20° (60° position). (3) Identical to (2) until post-meal; the head was then lowered to 30° (60°-30° position). Gastrointestinal motility was assessed as gastrointestinal sounds measured by sound-editing software. Digital plethysmography assessed autonomic nerve function as heart rate variability. The pressure ulcer risk was estimated as subjective comfort/discomfort using a visual analog scale. Gastrointestinal sounds increased post-meal. The 60°-30° position showed the highest number of sounds and longest cumulative sound duration. Post-meal, sympathetic activation was suggested in the 60° position, whereas vagal activity was relatively preserved in the 60°-30° position. The 60°-30° position was the most comfortable, and the 60° position was least comfortable. Lowering the head after a meal is beneficial to augment gastrointestinal motility and decrease the pressure ulcer risk. The 60° head-up position increases the pressure ulcer risk.
キーワード gastrointestinal sound body position autonomic nerve pressure ulcer patient care
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-12
71巻
6号
出版者 Okayama University Medical School
開始ページ 485
終了ページ 491
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29276221
JaLCDOI 10.18926/AMO/55582
フルテキストURL 71_6_459.pdf
著者 Sakaguchi, Masakiyo| Kinoshita, Rie| Endy Widya Putranto| I Made Winarsa Ruma| I Wayan Sumardika| Youyi, Chen| Tomonobu, Naoko| Yamamoto, Ken-ichi| Murata, Hitoshi|
抄録 The receptor for advanced glycation end products (RAGE) is involved in inflammatory pathogenesis. It functions as a receptor to multiple ligands such as AGEs, HMGB1 and S100 proteins, activating multiple intracellular signaling pathways with each ligand binding. The molecular events by which ligand-activated RAGE controls diverse signaling are not well understood, but some progress was made recently. Accumulating evidence revealed that RAGE has multiple binding partners within the cytoplasm and on the plasma membrane. It was first pointed out in 2008 that RAGE’s cytoplasmic tail is able to recruit Diaphanous-1 (Dia-1), resulting in the acquisition of increased cellular motility through Rac1/Cdc42 activation. We also observed that within the cytosol, RAGE’s cytoplasmic tail behaves similarly to a Toll-like receptor (TLR4)-TIR domain, interacting with TIRAP and MyD88 adaptor molecules that in turn activate multiple downstream signals. Subsequent studies demonstrated the presence of an alternative adaptor molecule, DAP10, on the plasma membrane. The coupling of RAGE with DAP10 is critical for enhancing the RAGE-mediated survival signal. Interestingly, RAGE interaction on the membrane was not restricted to DAP10 alone. The chemotactic G-protein-coupled receptors (GPCRs) formyl peptide receptors1 and 2 (FPR1 and FPR2) also interacted with RAGE on the plasma membrane. Binding interaction between leukotriene B4 receptor 1 (BLT1) and RAGE was also demonstrated. All of the interactions affected the RAGE signal polarity. These findings indicate that functional interactions between RAGE and various molecules within the cytoplasmic area or on the membrane area coordinately regulate multiple ligand-mediated RAGE responses, leading to typical cellular phenotypes in several pathological settings. Here we review RAGE’s signaling diversity, to contribute to the understanding of the elaborate functions of RAGE in physiological and pathological contexts.
キーワード receptor for advanced glycation end products RAGE adaptor protein signal transduction inflammatory pathogenesis
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2017-12
71巻
6号
出版者 Okayama University Medical School
開始ページ 459
終了ページ 465
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29276218
JaLCDOI 10.18926/okadai-bun-kiyou/55579
タイトル(別表記) Die Brautbriefe von Sigmund Freud und Martha Bernays (4): Freuds persönliches Liebesleben als Grundlage der Psychoanalyse
フルテキストURL jfl_068_(001)_(015).pdf
著者 金関 猛|
出版物タイトル 岡山大学文学部紀要
発行日 2017-12-22
68巻
開始ページ (1)
終了ページ (15)
ISSN 0285-4864
関連URL http://ousar.lib.okayama-u.ac.jp/55224
言語 日本語
論文のバージョン publisher
JaLCDOI 10.18926/okadai-bun-kiyou/55572
タイトル(別表記) A Post-Skinnerian Perspective in Psychology (26): Old Age as a Radical Behaviorist
フルテキストURL jfl_068_001_017.pdf
著者 長谷川 芳典|
抄録  本稿は、行動分析学の視点から、高齢者のライフスタイルの構築と終末に関する有用な知見を提供することを目的とする。このテーマは、 (1)スキナーの幸福観の概要と高齢者への適用 (2)選択機会と高齢者の行動的QOL (3)複数の行動のまとまりから構成される「活動」概念に基づいて、より巨視的な観点から高齢者のライフスタイルの構築を考える (4)終末期における不安や恐怖への対処 という4つの観点から総合的に検討する必要があると考えるが、本稿では紙幅の制限により、(2)についてはすでに長谷川(2012, 2013)で論じているのでここでは省略し、また(1)と(4)は概略を述べるにとどめ、新しい概念を取り入れた(3)について重点的に取り上げていくことにしたい。
出版物タイトル 岡山大学文学部紀要
発行日 2017-12-22
68巻
開始ページ 1
終了ページ 17
ISSN 0285-4864
関連URL http://ousar.lib.okayama-u.ac.jp/55220
言語 日本語
論文のバージョン publisher
NAID 120006370700
フルテキストURL jfl_068_contents.pdf
著者 岡山大学文学部|
出版物タイトル 岡山大学文学部紀要
発行日 2017-12-22
68巻
ISSN 0285-4864
言語 日本語
論文のバージョン publisher
フルテキストURL K0005592_other1.pdf
著者 Hinamoto, Norikazu| Maeshima, Yohei| Yamasaki, Hiroko| Nasu, Tatsuyo| Saito, Daisuke| Watatani, Hiroyuki| Ujike, Haruyo| Tanabe, Katsuyuki| Masuda, Kana| Arata, Yuka| Sugiyama, Hitoshi| Sato, Yasufumi| Makino, Hirofumi|
備考 学位審査副論文|
発行日 2014-09-25
出版物タイトル Plos One
9巻
9号
出版者 Public Library of Science
開始ページ e107934
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/
論文のバージョン publisher
PubMed ID 25255225
DOI 10.1371/journal.pone.0107934
Web of Science KeyUT 000344862300045
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0107934 isPartOf http://ousar.lib.okayama-u.ac.jp/55517