検索結果 1433 件
著者 | Tamura, Hideo| |
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発行日 | 2016-01 |
出版物タイトル | Mathematical Journal of Okayama University |
巻 | 58巻 |
号 | 1号 |
資料タイプ | 学術雑誌論文 |
JaLCDOI | 10.18926/mjou/53917 |
著者 | Tamura, Hideo| |
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発行日 | 2016-01 |
出版物タイトル | Mathematical Journal of Okayama University |
巻 | 58巻 |
号 | 1号 |
資料タイプ | 学術雑誌論文 |
JaLCDOI | 10.18926/mjou/53916 |
JaLCDOI | 10.18926/AMO/53907 |
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フルテキストURL | 69_6_333.pdf |
著者 | Ito, Maiko| Shien, Tadahiko| Kaji, Mitsumasa| Mizoo, Taeko| Iwamoto, Takayuki| Nogami, Tomohiro| Motoki, Takayuki| Taira, Naruto| Doihara, Hiroyoshi| Miyoshi, Shinichiro| |
抄録 | We evaluated the usefulness of preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) examinations to predict the pathological features in primary breast cancer. In particular, we evaluated the correlation between the maximum standardized uptake values (SUVmax) obtained by 18F-FDG PET/CT and the Ki67 expression in estrogen receptor (ER)-positive invasive ductal carcinoma (IDC). Primary IDC patients operated between March 2009 and July 2013 at Okayama University Hospital were enrolled. We evaluated the correlations between the SUVmax and age, postoperative pT, histological grade, lymph vascular invasion, status of hormone receptor, human epidermal growth factor receptor 2 (HER2), Ki67 expression and node status. The Ki67 expression was classified as high (>14%) versus low (<14%). We enrolled 138 patients with IDC. Their median SUVmax was 3.85 (range:0-52.57). In a univariate analysis, the SUVmax was significantly related to age, pT, histological grade, lymphovascular invasion, hormone receptor status, HER2 status, node status and Ki67. In the 113 patients with ER-positive IDC, there was a significant correlation between Ki67 and SUVmax (p=0.0030). The preoperative 18F-FDG PET/CT results of IDC patients had significant relationships with pathological status parameters. The determination of the preoperative SUVmax might help classify Luminal A and Luminal B patients among luminal-type breast cancer patients. |
キーワード | breast cancer invasive ductal carcinoma 18F-fluorodeoxyglucose positron emission tomography/computed tomography maximum standardized uptake values clinicopathological features |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2015-12 |
巻 | 69巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 333 |
終了ページ | 338 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 26690243 |
Web of Science KeyUT | 000368434500002 |
著者 | 榊原 一郎| |
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発行日 | 2015-09-30 |
出版物タイトル | |
資料タイプ | 学位論文 |
タイトル(別表記) | A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection |
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フルテキストURL | 127_213.pdf |
著者 | 安井 和也| 楳田 祐三| 熊野 健二郎| 田端 雅弘| 大塚 文男| 八木 孝仁| 藤原 俊義| |
抄録 | A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs. |
キーワード | 異所性褐色細胞腫(ectopic pheochromocytoma) 化学療法(chemo therapy) 131I-MIBG |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2015-12-01 |
巻 | 127巻 |
号 | 3号 |
開始ページ | 213 |
終了ページ | 218 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.127.213 |
言語 | 日本語 |
著作権者 | Copyright (c) 2015 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.127.213 |
NAID | 130005116814 |
タイトル(別表記) | Non-high-output cardiac failure in patients undergoing hemodialysis through an arteriovenous shunt |
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フルテキストURL | 127_203.pdf |
著者 | 鵜川 豊世武| |
抄録 | Background: Hemodialysis-related heart failure has been considered to be associated with excessive blood flow through the arteriovenous (AV) shunt used for vascular access. However, some patients undergoing dialysis have heart failure in the absence of an increase in cardiac output (CO) related to shunt blood-flow loading because the loading cannot be compensated for by increasing CO. This condition may be challenging to manage ; thus, early diagnosis is important. Methods and Results: Twelve patients (mean age, 71 years ; 9 men) with end-stage renal disease, dialysis-related heart failure, a high brain natriuretic peptide (BNP) level, and a mean New York Heart Association (NYHA) class of II underwent AV shunt closure. Their cardiac index (CI), pre- and post-dialysis BNP levels, and several cardiac variables were assessed pre- and postoperatively. All patients achieved relief of heart failure symptoms and a reduction in NYHA class after AV closure, but six patients had a postoperative increase in CI (the "non-high-output" cardiac failure group), whereas the other six had a decrease in CI (the "high-output" cardiac failure group). The high-output patients had greater improvements in BNP levels and most cardiac variables compared to the non-high-output group ; therefore, the heart failure in the non-high-output patients was considered more serious than that in the high-output group. Conclusions: The selection of effective strategies for treating dialysis-related heart failure may depend partly on identifying which patients have non-high-output failure. Such identification requires serial measurements of BNP levels and evaluations of cardiac variables other than the ejection fraction. |
キーワード | 心拍出量(cardiac output) 心不全(heart failure) 脳性ナトリウム利尿ペプチド(brain natriuretic peptide) 非過大シャント心不全(non-high-output cardiac failure) 腎臓(kidney) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2015-12-01 |
巻 | 127巻 |
号 | 3号 |
開始ページ | 203 |
終了ページ | 207 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.127.203 |
言語 | 日本語 |
著作権者 | Copyright (c) 2015 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.127.203 |
NAID | 130005116810 |
タイトル(別表記) | Basic and clinical research regarding vascular endothelial function |
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フルテキストURL | 127_187.pdf |
著者 | 塚原 宏一| |
キーワード | アルギニン代謝 一酸化窒素 ガス生物学 血管内皮学 酸化ストレス |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2015-12-01 |
巻 | 127巻 |
号 | 3号 |
開始ページ | 187 |
終了ページ | 195 |
ISSN | 0030-1558 |
言語 | 日本語 |
著作権者 | Copyright (c) 2015 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.127.187 |
NAID | 130005116819 |
JaLCDOI | 10.18926/AMO/53672 |
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フルテキストURL | 69_5_267.pdf |
著者 | Inada, Ryo| Nagasaka, Takeshi| Kondo, Yoshitaka| Watanabe, Ayako| Toshima, Toshiaki| Kubota, Nobuhito| Kikuchi, Satoru| Ishida, Michihiro| Kuroda, Shinji| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
抄録 | The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time. |
キーワード | laparoscopic surgery total proctocolectomy open proctocolectomy ulcerative colitis case-matched study |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2015-10 |
巻 | 69巻 |
号 | 5号 |
出版者 | Okayama University Medical School |
開始ページ | 267 |
終了ページ | 273 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 26490023 |
Web of Science KeyUT | 000365519600002 |
著者 | 永井 伊作| Watanabe, Keigo| |
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発行日 | 2015-09-28 |
出版物タイトル | IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) |
資料タイプ | 会議発表論文 |
タイトル(別表記) | Successful laparoscopic resection of a cecal tumor in a 95-year-old man |
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フルテキストURL | 127_117.pdf |
著者 | 渡邉 彩子| 稲田 涼| 永坂 岳司| 八木 朝彦| 松本 聖| 戸嶋 俊明| 菊池 覚次| 黒田 新士| 近藤 喜太| 母里 淑子| 岸本 浩行| 藤原 俊義| |
抄録 | We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials (RCTs) revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients. |
キーワード | 超高齢者(extremely elderly patient) 大腸癌(colorectal cancer) 腹腔鏡手術(laparoscopic surgery) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2015-08-03 |
巻 | 127巻 |
号 | 2号 |
開始ページ | 117 |
終了ページ | 121 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.127.117 |
言語 | 日本語 |
著作権者 | Copyright (c) 2015 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.127.117 |
NAID | 130005096253 |
JaLCDOI | 10.18926/AMO/53337 |
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フルテキストURL | 69_2_87.pdf |
著者 | Murayama, Hidehiko| Nakata, Yusei| Kanazawa, Akane| Watanabe, Hirokazu| Shigemitsu, Yusuke| Iwasaki, Yuka| Tokorodani, Chiho| Miyazawa, Mari| Nishiuchi, Ritsuo| Kikkawa, Kiyoshi| |
抄録 | Ventriculoperitoneal shunts (VPSs) are used for the treatment of hydrocephalus. Here we analyzed the outcomes of VPS placements in 24 infants to determine the risk factors for shunt failure. The infants had undergone the initial VPS operation in our hospital between March 2005 and December 2013. They were observed until the end of January 2014. We obtained Kaplan-Meier curves and performed a multivariate Cox regression analysis of shunt failure. Of the 24 cases, the median (range) values for gestational age, birth weight, and birth head circumference (HC) were 37 (27-39) wks, 2,736 (686-3,788) g, and 35.3 (23.0-45.3) cm, respectively. The total number of shunt procedures was 45. Shunt failure rates were 0.51/shunt and 0.0053/shunt/year. Shunt infection rates were 0.13/shunt and 0.0014/shunt/year. The Kaplan-Meier analysis revealed an increased risk for shunt failure in infants <1 month old or in the HC >90オtile. The Cox regression analysis yielded hazard ratios (HRs) of 2.93 (95オ confidence interval (CI), 0.96-10.95, p=0.059) for age <1 month, and 4.46 (95オCI:1.20-28.91,p=0.023) for the HC >90オtile. The multivariate Cox regression analysis showed adjusted HRs of 17.56 (95オCI:2.69-202.8, p=0.001) for age <1 month, and 2.95 (95オCI:0.52-24.84, p=0.228) for the HC >90オtile. Our findings thus revealed that the risk factors for shunt failure in infants include age <1 month at the initial VPS placement. |
キーワード | head circumference shunt failure shunt infection ventriculoperitoneal shunt |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2015-04 |
巻 | 69巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 87 |
終了ページ | 93 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 25899630 |
Web of Science KeyUT | 000353181700003 |
タイトル(別表記) | Cholelithiasis with a cholecystoduodenal fistula complicated with paroxysmal nocturnal hemoglobinuria |
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フルテキストURL | 127_35.pdf |
著者 | 加藤 卓也| 松川 啓義| 塩崎 滋弘| 藤 智和| 藤原 康宏| 二宮 基樹| |
抄録 | In cases of paroxysmal nocturnal hemoglobinuria (PNH), attention must be paid to potential complications such as thrombosis and hemolysis due to perioperative stress and infection from complement activation. Here we present the case of a 61-year-old Japanese woman with PNH. We made the diagnosis of PNH when she was 28 years old, and we administered repeated steroid medication and erythrocyte transfusion. The patient's cholecystocholedocholithiasis with a cholecystoduodenal fistula was diagnosed based on a survey of the right hypochondriac pain. We performed endoscopic nasobiliary drainage (ENBD) for the prophylaxis of perioperative infection, plus a cholecystectomy and fistulectomy. There were no complications, including hemolysis attack, infection, thrombosis with irrigation erythrocyte transfusion, steroid cover, or the need for heparin administration during the perioperative period. The reduction of the complement activation is necessary in the perioperative management of PNH patients. The prevention of the development of acidosis and hypoxemia, the selection of washed red blood cells, steroid use, appropriate infection measures and thrombosis prophylaxis are all important for the prevention of complications. |
キーワード | 発作性夜間血色素尿症(PNH)(paroxysmal nocturnal hemoglobinuria (PNH)) 胆嚢十二指腸瘻(cholecystoduodenal fistula) 溶血発作(hemolysis) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2015-04-01 |
巻 | 127巻 |
号 | 1号 |
開始ページ | 35 |
終了ページ | 39 |
ISSN | 0030-1558 |
関連URL | http://www.okayama-u.ac.jp/user/oma/ |
言語 | 日本語 |
著作権者 | Copyright (c) 2015 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.127.35 |
NAID | 130005068351 |
タイトル(別表記) | Surgically treated Zenker’s diverticulum: Diverticulectomy and cricopharyngeal myotomy |
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フルテキストURL | 127_19.pdf |
著者 | 二宮 卓之| 金谷 信彦| 勝田 浩| 田中屋 宏爾| 青木 秀樹| 竹内 仁司| |
抄録 | Zenker's diverticulum is a very rare disease among gastorointestinal diverticulum. We report a case of Zenker's diverticulum successfully treated with diverticulectomy and cricophalyngial myotomy. A 71-year-old male complained of aspirating water for two years. He was diagnosed as Zenker's diverticulum. Due to his severe symptoms, the operation was performed in an open-neck approach. The left recurrent laryngeal nerve was identified and preserved. An incision was made in the diverticulum wall, and the internal diameter of normal cervical esophagus was measured. The diverticulum was then excised with an automatic suture device in the minor axis direction of the esophagus. A cricopharyngeal myotomy was conducted, because this muscle was fibrotic and stiffened. The patient's symptoms disappeared after the operation. Diverticulectomy and cricopharyngeal myotomy through an open-neck approach is a safe and reliable method that follows, direct access to the diverticulum and recurrent laryngeal nerve. |
キーワード | Zenker憩室(Zenker’s diverticulum) 輪状咽頭筋切開術(cricopharyngeal myotomy) 頚部アプローチ(open-neck approach) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2015-04-01 |
巻 | 127巻 |
号 | 1号 |
開始ページ | 19 |
終了ページ | 23 |
ISSN | 0030-1558 |
言語 | 日本語 |
著作権者 | Copyright (c) 2015 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.127.19 |
NAID | 130005068344 |
JaLCDOI | 10.18926/ESR/53194 |
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タイトル(別表記) | Aerosol observation at Okayama with Skyradiometer and LIDAR |
フルテキストURL | esr_021_1_013_021.pdf |
著者 | 永松 慎平| 江川 大貴| 塚本 修| |
抄録 | Aerosol is one of the controlling parameter for the global climate and also effects on local health hazards. The measurement of the aerosol was originally carried out as in-situ sampling and mass weight measurement including chemical analysis. Recently, remote sensing method is applied as satellite remote sensing and surface based remote sensing. Skyradiometer and LIDAR are surface based remote sensing system. Skyradiometer measures solar radiation as direct and scattered solar radiation affected by aerosols. LIDAR emit laser beam upward and it is backscattered by overlying aerosols. The backscattered light is received by a telescope and vertical distributions of the aerosols are obtained. These measurements require atmospheric radiation physics. A Skyradiometer and a LIDAR were operated continuously at Okayama University campus and aerosol parameters were obtained from both of the system. Seasonal variations of the AOT (Aerosol Optical Thickness) and Angstrom parameter (α) are evaluated. During some dust events (e.g. yellow sand and PM2.5), time variations of these parameters were identified from both of the measurement system. |
キーワード | Aerosol Skyradiometer LIDAR Aerosol Optical Thickness (AOT) |
出版物タイトル | Okayama University Earth Science Report |
発行日 | 2014-12-27 |
巻 | 21巻 |
号 | 1号 |
開始ページ | 13 |
終了ページ | 21 |
ISSN | 1340-7414 |
言語 | 日本語 |
著作権者 | © 2014 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
論文のバージョン | publisher |
NAID | 120005567873 |
著者 | 安場 健一郎| |
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発行日 | 2015-02-01 |
出版物タイトル | 岡山大学農学部学術報告 |
巻 | 104巻 |
資料タイプ | 紀要論文 |
著者 | 上村 一雄| 長田 臨| 菊本 愛生| Sharmin, Sultana| 若井 暁| 金尾 忠芳| |
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発行日 | 2015-02-01 |
出版物タイトル | 岡山大学農学部学術報告 |
巻 | 104巻 |
資料タイプ | 紀要論文 |
著者 | Kondo, Yoshitaka| Nagasaka, Takeshi| Kobayashi, Satoru| Kobayashi, Naoya| Fujiwara, Toshiyoshi| |
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発行日 | 2014-03 |
出版物タイトル | Hepato-Gastroenterology |
巻 | 61巻 |
号 | 130号 |
資料タイプ | 学術雑誌論文 |
著者 | Yamada, Eiji| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Sakuma, Leon| Takaoka, Munenori| Yamada, Takako| Noma, Kazuhiro| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Tanabe, Shunsuke| Nagasaka, Takeshi| Fujiwara, Toshiyoshi| Naomoto, Yoshio| |
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発行日 | 2012-12 |
出版物タイトル | Journal of Surgical Research |
巻 | 178巻 |
号 | 2号 |
資料タイプ | 学術雑誌論文 |
タイトル(別表記) | Giant rectal gastrointestinal stromal tumor successfully resected by abdominoperineal resection combined with posterior vaginal wall resection |
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フルテキストURL | 126_217.pdf |
著者 | 岩川 和秀| 西江 学| 徳永 尚之| 宮宗 秀明| 岩垣 博巳| |
抄録 | We report a case of giant rectal gastrointestinal stromal tumor (GIST) successfully resected by abdominoperineal resection combined with posterior vaginal wall resection. Our patient was a 79-year-old woman had been diagnosed as having von Recklinghausen disease at the age of 30 years. In 2006, a computed tomography (CT) scan revealed a tumor originating from the posterior wall of the rectum. In June 2010, she was admitted to our hospital with the chief complaint of bloody stool. A CT scan revealed a giant tumor that had increased to 9cm in size. Colonoscopy demonstrated a submucosal tumor, which was subsequently diagnosed by biopsy as a GIST. Due to the patient's continuous bleeding and abdominal pain, an emergent abdominoperineal resection was performed at that time. The tumor, which measured 8×9cm, was immunohistochemically positive for c-kit and CD34. Concomitant resection of the posterior wall of the vagina via the perineal approach provided a wide area to expose the tumor for a safe operation. The patient has been well with no sign of recurrence since the operation. This procedure is recommended as a useful approach for giant rectal GISTs or rectal cancer with invasion of the posterior pelvic wall. |
キーワード | 巨大直腸GIST(giant rectal GIST) 腹会陰式直腸切断術(abdominoperineal resection) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2014-12-01 |
巻 | 126巻 |
号 | 3号 |
開始ページ | 217 |
終了ページ | 221 |
ISSN | 0030-1558 |
言語 | 日本語 |
著作権者 | Copyright (c) 2014 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.126.217 |
NAID | 130004903245 |
著者 | 箕輪 弘嗣| 宗澤 良臣| 鈴木 和彦| |
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発行日 | 2012-10-15 |
出版物タイトル | 安全工学 |
巻 | 51巻 |
号 | 5号 |
資料タイプ | 学術雑誌論文 |