検索結果 469 件
| フルテキストURL | BreastCancer_24_4_593.pdf BreastCancer_24_4_593_tbl_fig.pdf |
|---|---|
| 著者 | Yatake, Hidetoshi| Sawai, Yuka| Nishi, Toshio| Nakano, Yoshiaki| Nishimae, Ayaka| Katsuda, Toshizo| Yabunaka, Koichi| Takeda, Yoshihiro| Inaji, Hideo| |
| キーワード | Breast cancer Direct methods Mammography Mask methods Stereotactic vacuum assisted biopsy |
| 発行日 | 2017-07 |
| 出版物タイトル | Breast Cancer |
| 巻 | 24巻 |
| 号 | 4号 |
| 出版者 | Japanese Breast Cancer Society |
| 開始ページ | 593 |
| 終了ページ | 600 |
| ISSN | 1340-6868 |
| NCID | AA1103354X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | author |
| PubMed ID | 27878446 |
| DOI | 10.1007/s12282-016-0743-y |
| Web of Science KeyUT | 000404221100015 |
| 関連URL | https://doi.org/10.1007/s12282-016-0743-y |
| タイトル（別表記） | The 2016 Incentive Award of the Okayama Medical Association in Cancer Research (2016 Hayashibara Prize and Yamada Prize) |
|---|---|
| フルテキストURL | 129_89.pdf |
| 著者 | 藤田 洋史| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-08-01 |
| 巻 | 129巻 |
| 号 | 2号 |
| 開始ページ | 89 |
| 終了ページ | 91 |
| ISSN | 0030-1558 |
| 関連URL | https://doi.org/10.4044/joma.129.89 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.89 |
| NAID | 130006039368 |
| JaLCDOI | 10.18926/AMO/55210 |
|---|---|
| フルテキストURL | 71_3_259.pdf |
| 著者 | Kawana, Shinichi| Yamamoto, Hiromasa| Maki, Yuho| Sugimoto, Seiichiro| Toyooka, Shinichi| Miyoshi, Shinichiro| |
| 抄録 | Primary sternal chondrosarcoma is a rare malignant tumor that is refractory to chemotherapy and radiation. Effective therapy is radical resection of the tumor. We present two patients with primary sternal chondrosarcoma who underwent a radical resection of the lower half of the sternum and bilateral ribs, followed by reconstruction with 2 sheets of polypropylene mesh layered orthogonally. The patients have maintained almost the same pulmonary function as preoperative values, with stability of the chest wall. Although there are various ways to reconstruct the anterior chest wall, reconstruction with polypropylene mesh layered orthogonally is an easy-to-use and sufficient method. |
| キーワード | chondrosarcoma sternum reconstruction polypropylene mesh |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-06 |
| 巻 | 71巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 259 |
| 終了ページ | 262 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28655947 |
| JaLCDOI | 10.18926/AMO/55206 |
|---|---|
| フルテキストURL | 71_3_233.pdf |
| 著者 | Shimoyama, Kyoko| Osako, Tomo| Mitsuhashi, Toshiharu| Akiyama, Futoshi| Iwase, Takuji| |
| 抄録 | Ductal carcinoma in situ (DCIS) of the breast has no potential to metastasize, but over 20% of cases preoperatively diagnosed as DCIS are upstaged on final pathology. The rates of upstaging and the predictors for invasion on final pathology were evaluated. For 240 primary breast cancers, radiological findings on mammography, ultrasonography, and magnetic resonance imaging were investigated along with pathological and clinical information. Univariate and multivariate analyses were performed to identify predictors of potential invasion. Of the 240 breast cancers, 68 (28.3%) showed invasion on final pathology, and 5 (2.5%) had sentinel node metastasis. The multivariate analysis identified five independent predictors: non-mass lesions >2.4 cm on ultrasonography (odds ratio [OR] 2.84, 95% confidence interval [CI] 1.02-7.95, p=0.047), comedo-type histology (OR 6.89, 95% CI 1.89-25.08, p<0.01), solid-type histology (OR 7.97, 95% CI 2.08-30.49, p<0.01), palpable mass (OR 2.63, 95% CI 1.05-6.64, p=0.04), and bloody nipple discharge (OR 4.61, 95% CI 1.20-17.66, p=0.02). These five predictors were associated with invasion on final pathology and may help select candidates for sentinel node biopsy. |
| キーワード | breast cancer DCIS breast needle biopsy imaging examination sentinel node biopsy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-06 |
| 巻 | 71巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 233 |
| 終了ページ | 240 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28655943 |
| フルテキストURL | K0005517_abstract_review.pdf K0005517_fulltext.pdf K0005517_summary.pdf |
|---|---|
| 著者 | 松井 美由紀| |
| 発行日 | 2017-03-24 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5517号 |
| 学位授与年月日 | 2017-03-24 |
| 学位・専攻分野 | 博士（看護学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | K0005471_abstract_review.pdf K0005471_summary.pdf K0005471_fulltext.pdf |
|---|---|
| 著者 | 三好 雄一郎| |
| 発行日 | 2017-03-24 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5471号 |
| 学位授与年月日 | 2017-03-24 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005470_abstract_review.pdf K0005470_summary.pdf K0005470_fulltext.pdf |
|---|---|
| 著者 | 原 暁生| |
| 発行日 | 2017-03-24 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5470号 |
| 学位授与年月日 | 2017-03-24 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/54978 |
|---|---|
| フルテキストURL | 71_2_105.pdf |
| 著者 | Shinya, Takayoshi| Tanaka, Takashi| Soh, Junichi| Matsushita, Toshi| Sato, Shuhei| Toyooka, Shinichi| Yoshino, Tadashi| Miyoshi, Shinichiro| Kanazawa, Susumu| |
| 抄録 | We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy. |
| キーワード | thymic epithelial neoplasm thymic carcinoma thymoma dual-time-point PET/CT chest CT |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 105 |
| 終了ページ | 112 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420891 |
| タイトル（別表記） | The 69th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery |
|---|---|
| フルテキストURL | 129_63.pdf |
| 著者 | 三好 新一郎| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-04-03 |
| 巻 | 129巻 |
| 号 | 1号 |
| 開始ページ | 63 |
| 終了ページ | 64 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.63 |
| NAID | 130005632076 |
| タイトル（別表記） | Precision Medicine |
|---|---|
| フルテキストURL | 129_59.pdf |
| 著者 | 冨田 秀太| 豊岡 伸一| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-04-03 |
| 巻 | 129巻 |
| 号 | 1号 |
| 開始ページ | 59 |
| 終了ページ | 60 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.59 |
| NAID | 130005632074 |
| 著者 | Yasuda, Yukiko| Sakai, Akiko| Ito, Sachio| Sasai, Kaori| Yamamoto, Hiromasa| Matsubara, Nagahide| Ouchida, Mamoru| Katayama, Hiroshi| Shimizu, Kenji| |
|---|---|
| 発行日 | 2017-02 |
| 出版物タイトル | Acta Medica Okayama |
| 巻 | 71巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/54826 |
| JaLCDOI | 10.18926/AMO/54816 |
|---|---|
| フルテキストURL | 70_6_507.pdf |
| 著者 | Torigoe, Hidejiro| Toyooka, Shinichi| Yamamoto, Hiromasa| Soh, Junichi| Miyoshi, Shinichiro| |
| 抄録 | We present the case of a 65-year-old Japanese man diagnosed with chronic empyema (without a bronchopleural fistula) that occurred 7 months after he underwent an extrapleural pneumonectomy for right malignant pleural mesothelioma (MPM). Following thoracic drainage and irrigation for 1 month, we performed surgery by a thoracoscopic approach, in light of his general condition. We performed debridement and removal of the Gore-Tex polytetrafluoroethylene (PTFE) patch that had been used for the reconstruction of the diaphragm and the pericardium. The empyema had not relapsed when he died from recurrence of the MPM at 4 months after the thoracoscopic surgery. This patientʼs case suggests that thoracoscopic debridement and patch removal can be a therapeutic option for not only early-stage (exudative or fibrinopurulent) empyema but also late-stage (organized and chronic) empyema without a bronchopleural fistula, particularly for patients in poor general condition. |
| キーワード | empyema chronic extrapleural pneumonectomy thoracoscopic debridement patch removal |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-12 |
| 巻 | 70巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 507 |
| 終了ページ | 510 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28003678 |
| 著者 | 小野 美穂| |
|---|---|
| 発行日 | 2016-09-30 |
| 資料タイプ | 学位論文 |
| 著者 | 谷口 恒平| |
|---|---|
| 発行日 | 2016-09-30 |
| 資料タイプ | 学位論文 |
| 著者 | 森田 瑞樹| 豊岡 伸一| |
|---|---|
| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 一般雑誌記事 |
| 著者 | 小橋 研太| 石井 博| 西山 加那子| 松三 雄騎| 羽田野 雅英| 藤原 雅光| 黒河 達雄| 常光 謙輔| |
|---|---|
| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 重安 邦俊| |
|---|---|
| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/54607 |
|---|---|
| フルテキストURL | 70_5_425.pdf |
| 著者 | Tamura, Tomoki| Hirata, Taizo| Tabata, Masahiro| Hinotsu, Shiro| Hamada, Akinobu| Motoki, Takayuki| Iwamoto, Takayuki| Mizoo, Taeko| Nogami, Tomohiro| Shien, Tadahiko| Taira, Naruto| Matsuoka, Junji| Doihara, Hiroyoshi| |
| 抄録 | Docetaxel is a standard treatment for patients with advanced or recurrent breast cancer. The recommended dose is 60 to 100 mg/m2. Previous study have shown that the tumor response rates of patients who received docetaxel monotherapy at doses of 60, 75, and 100 mg/m2 were 22.1% , 23.3% , and 36.0% , respectively, and there was a significant relationship between the dose and response. In Europe and the United States, docetaxel is approved at a dose of 100 mg/m2, and Japanese guidelines also recommend a dose of 100 mg/m2. However, the approved dose in Japan is up to 75 mg/m2. We have launched a phase I trial evaluating 100 mg/m2 docetaxel in patients with advanced or relapsed breast cancer. The major eligibility criteria are as follows: age ≥20 years, pathologically diagnosed breast cancer, recurrent or advanced breast cancer, a good performance status, and HER2 [human epidermal growth factor receptor 2] negative. The primary endpoint is demonstrated safety of 100 mg/m2 docetaxel. This study will clarify whether 100mg/m2 docetaxel can be administrated safely in Japanese patients with advanced or recurrent breast cancer. |
| キーワード | breast cancer phase I trial docetaxel |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-10 |
| 巻 | 70巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 425 |
| 終了ページ | 427 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27777441 |
| Web of Science KeyUT | 000388098700018 |
| JaLCDOI | 10.18926/AMO/54514 |
|---|---|
| フルテキストURL | 70_4_327.pdf |
| 著者 | Watanabe, Mototsugu| Yamamoto, Hiromasa| Eikawa, Shingo| Shien, Kazuhiko| Shien, Tadahiko| Soh, Junichi| Hotta, Katsuyuki| Wada, Jun| Hinotsu, Shiro| Fujiwara, Toshiyoshi| Kiura, Katsuyuki| Doihara, Hiroyoshi| Miyoshi, Shinichiro| Udono, Heiichiro| Toyooka, Shinichi| |
| 抄録 | A study to evaluate the effect of metformin on the immune system was commenced in July 2014. Metformin is one of the most commonly prescribed drugs for type 2 diabetes, and previous studies have reported that metformin has an anti-tumor effect. The aim of this study is to evaluate the efficacy of metformin on the immune system in human cancer patients in vivo. The primary outcome parameter will be the rate change in the population of CD8＋ T cells, which produce multiple cytokines. |
| キーワード | metformin CD8＋ T cells cancer immunology |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 327 |
| 終了ページ | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549683 |
| Web of Science KeyUT | 000384748600018 |