ID | 56122 |
フルテキストURL | |
著者 |
Eguchi , Taka
Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
publons
researchmap
Prince, Thomas
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute
Wegiel, Barbara
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School
Calderwood, Stuart K.
Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School
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抄録 | Myeloid zinc finger 1 (MZF1) belongs to the SCAN-Zinc Finger (SCAN-ZF) transcription factor family that has recently been implicated in a number of types of cancer. Although the initial studies concentrated on the role of MZF1 in myeloid differentiation and leukemia, the factor now appears to be involved in the etiology of major solid tumors such as lung, cervical, breast, and colorectal cancer. Here we discuss the regulation of MZF1 that mediated its recruitment and activation in cancer, concentrating on posttranslational modification by phosphorylation, and sumoylation, formation of promyelocytic leukemia nuclear bodies and its association with co-activators and co-repressors.
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キーワード | CANCER
FINGER-1
INVASION
MYELOID
NUCLEAR BODY
SUMO
ZINC
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発行日 | 2015-04-21
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出版物タイトル |
Journal of cellular biochemistry
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巻 | 116巻
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号 | 10号
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出版者 | Wiley
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開始ページ | 2146
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終了ページ | 2154
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ISSN | 0730-2312
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NCID | AA1052210X
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資料タイプ |
学術雑誌論文
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言語 |
日本語
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OAI-PMH Set |
岡山大学
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論文のバージョン | author
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1002/jcb.25203
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