フルテキストURL Chemistry_22_6_1979.pdf
著者 Takamura, Hiroyoshi| Fujiwara, Takayuki| Kawakubo, Yohei| Kadota, Isao| Uemura, Daisuke|
抄録 Stereoselective and streamlined synthesis of the proposed C79-C104 fragment 2 of symbiodinolide (1), a polyol marine natural product with a molecular weight of 2860, was achieved. In the synthetic route, the proposed C79-C104 fragment 2 was synthesized by utilizing a Julia-Kocienski olefination and subsequent Sharpless asymmetric dihydroxylation as key transformations in a convergent manner. Detailed comparison of the 13 C NMR chemical shifts between the natural product and the synthetic C79-C104 fragment 2 revealed that the stereostructure at the C91-C99 carbon chain moiety of symbiodinolide (1) should be reinvestigated.
キーワード macrocycles natural products polyols stereoselective synthesis structure elucidation
備考 This is an article published by Wiley-VCH We appreciate JGC-S Scholarship Foundation, The Naito Foundation, The Sumitomo Foundation, and The Uehara Memorial Foundation for their financial supports. This research was supported by a Grant-in Aid for Scientific Research (No. 24710250) from the Japan Society for the Promotion of Science (JSPS)
発行日 2016-02
出版物タイトル Chemistry - A European Journal
22巻
6号
出版者 Wiley-VCH
開始ページ 1979
終了ページ 1983
ISSN 0947-6539
NCID AA11076269
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 26661715
DOI 10.1002/chem.201503880
Web of Sience KeyUT 000368925200015
関連URL isVersionOf https://doi.org/10.1002/chem.201503880