このエントリーをはてなブックマークに追加
ID 48974
フルテキストURL
著者
Hyakutake, Toru Graduate School of Natural Science and Technology, Okayama University
Hashimoto, Yuki Graduate School of Natural Science and Technology, Okayama University
Yanase, Shinichiro Graduate School of Natural Science and Technology, Okayama University
Matsuura, Koji Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Naruse, Keiji Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
抄録
This paper describes a study in which numerical simulations were applied to improve the separation efficiency of a microfluidic-based sperm sorter. Initially, the motion of 31 sperm were modeled as a sinusoidal wave. The modeled sperm were expected to move while vibrating in the fluid within the microchannel. In this analysis, the number of sperm extracted at the outlet channel and the rate of movement of the highly motile sperm were obtained for a wide range of flow velocities within the microchannel. By varying the channel height, and the width and the position of the sperm-inlet channel, we confirmed that the separation efficiency was highly dependent on the fluid velocity within the channel. These results will be valuable for improving the device configuration, and might help to realize further improvements in efficiency in the future.
キーワード
Human reproduction
Microfluid
Numerical simulation
Separation efficiency
Sperm sorter
発行日
2009-02
出版物タイトル
Biomedical Microdevices
11巻
1号
出版者
Springer US
開始ページ
25
終了ページ
33
ISSN
1387-2176
資料タイプ
学術雑誌論文
プロジェクト
異分野融合先端研究コア
オフィシャル URL
http://link.springer.com/article/10.1007%2Fs10544-008-9207-2
言語
English
著作権者
© Springer Science+Business Media, LLC 2008
論文のバージョン
author
査読
有り
DOI
PubMed ID
Web of Sience KeyUT