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ID 48960
フルテキストURL
著者
Takahashi, Kazuo H. Research Core for Interdisciplinary Sciences, Okayama University
Okada, Yasukazu Graduate School of Environmental Science, Okayama University
Teramura, Kouhei Graduate School of Environmental Science, Okayama University
抄録
Developmental processes of organisms are programed to proceed in a finely regulated manner and finish within a certain period of time depending on the ambient environmental conditions. Therefore, variation in the developmental period under controlled genetic and environmental conditions indicates innate instability of the developmental process. In this study, we aimed to determine whether a molecular machinery exists that regulates the canalization of the developmental period and, if so, to test whether the same mechanism also stabilizes a morphological trait. To search for regions that influence the instability of the developmental period, we conducted genome-wide deficiency mapping with 441 isogenic deficiency strains covering 65.5% of the Drosophila melanogaster genome. We found that 11 independent deficiencies significantly increased the instability of the developmental period and 5 of these also significantly increased the fluctuating asymmetry of wing shape although there was no significant correlation between the instabilities of developmental period and wing shape in general. These results suggest that canalization processes of the developmental period and morphological traits are at least partially independent. Our findings emphasize the potential importance of temporal variation in development as an indicator of developmental stability and canalization and provide a novel perspective for understanding the regulation of phenotypic variability.
キーワード
developmental period
developmental stability
Drosophila melanogaster
wing shape
発行日
2011-08
出版物タイトル
Journal of Heredity
102巻
4号
出版者
Oxford University Press
開始ページ
448
終了ページ
457
ISSN
0022-1503
資料タイプ
学術雑誌論文
プロジェクト
異分野融合先端研究コア
オフィシャル URL
http://jhered.oxfordjournals.org/content/early/2011/04/27/jhered.esr026.short?rss=1
言語
English
著作権者
© The American Genetic Association. 2011. All rights reserved.
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