ID | 56868 |
JaLCDOI | |
フルテキストURL | |
著者 |
Yoshio, Kotaro
Department of Radiology, Kagawa Prefectural Central Hospital
Wakita, Akihisa
Division of Medical Physics, Euro MediTech Co. Ltd
Mitsuhashi, Toshiharu
Center for Innovative Clinical Medicine, Okayama University Hospital
Kitayama, Takahiro
Department of Radiology, Kagawa Prefectural Central Hospital
Hisazumi, Kento
Department of Radiology, Kagawa Prefectural Central Hospital
Inoue, Daisaku
Department of Radiology, Kagawa Prefectural Central Hospital
Tajiri, Nobuhisa
Department of Radiology, Kagawa Prefectural Central Hospital
Shiode, Tsuyoki
Department of Radiology, Kagawa Prefectural Central Hospital
Akaki, Shiro
Department of Radiology, Kagawa Prefectural Central Hospital
Kanazawa, Susumu
Department of Radiology, Okayama University Hospital
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抄録 | We investigated the feasibility of simultaneous integrated boost (SIB) volumetric modulated arc therapy (VMAT) using elective nodal irradiation (ENI) for middle or lower esophageal cancer and compared it with three-dimensional conformal radiotherapy (3D-CRT). The study included 15 patients. The prescribed doses included a standard dose (50.4 Gy) and a high dose (60 Gy) for the planning target volume (PTV) of the involved lesions. The objective of the whole lung volume receiving ≥ 20 Gy (V20Gy) was < 30%, and the mean lung dose (MLD) was < 20 Gy. The volumes of the lung receiving 5 Gy (V5Gy) and the heart receiving 30-50 Gy (V30-50Gy) were kept as low as reasonably achievable. As a result, SIB-VMAT showed superior dose conformity for the PTV (p<0.001). Although the lung V5Gy was significantly increased (p<0.001), the V20Gy and MLD showed no significant increase. The heart V30-50Gy showed a > 20% reduction in the mean against 3D-CRTs. Our results demonstrate the feasibility of SIB-VMAT for the treatment of middle or lower esophageal cancer with ENI. Although attention should be paid to the low-dose area of the lungs, SIB-VMAT would be a promising treatment option with improved outcomes for esophageal cancer.
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キーワード | esophageal cancer
middle and lower thoracic
volumetric modulated arc therapy,
3D-CRT
elective nodal irradiation
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2019-06
|
巻 | 73巻
|
号 | 3号
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出版者 | Okayama University Medical School
|
開始ページ | 247
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終了ページ | 257
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2019 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID |