| JaLCDOI | 10.18926/AMO/67869 |
|---|---|
| フルテキストURL | 78_6_439.pdf |
| 著者 | Yamashita, Mampei| Tanaka, Takayuki| Sumida, Yorihisa| Yamazaki, Shoto| Hara, Yuki| Fukuda, Akiko| Hisanaga, Makoto| Wakata, Koki| Araki, Masato| Eguchi, Susumu| |
| 抄録 | Gangrenous cholecystitis (GC) is classified as moderate acute cholecystitis according to the Tokyo Guidelines from 2018 (TG18). We evaluated the risk factors for GC and the outcomes of early cholecystectomy. A total of 136 patients who underwent emergency cholecystectomy for acute cholecystitis were retrospectively analyzed; 58 of these patients (42.6%) were diagnosed with GC (GC group) based on our retrospective pathologic diagnosis. We comparatively evaluated the patient backgrounds and surgical outcomes between the GC group and non-GC group. The GC group was significantly older and included more hypertensive patients than the non-GC group. The GC group was prescribed more antibiotics as initial treatment than the non-GC group, and they had more days between onset and surgery. The preoperative white blood cell count and C-reactive protein values were significantly higher in the GC group than in the non-GC group, and these values were predictive factors for GC. Cholecystectomy required a longer operation time and caused greater blood loss in the GC group. The GC group also had longer hospitalization times than the non-GC group; however, no significant differences were observed in terms of postoperative complications. In conclusion, gangrenous changes should be assessed when diagnosing cholecystitis, and appropriate treatment, such as surgery or drainage, should be undertaken. |
| キーワード | gangrenous cholecystitis acute cholecystitis laparoscopic cholecystectomy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-12 |
| 巻 | 78巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 439 |
| 終了ページ | 447 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39719316 |
| Web of Science KeyUT | 001397799300002 |
| JaLCDOI | 10.18926/AMO/67868 |
|---|---|
| フルテキストURL | 78_6_429.pdf |
| 著者 | Kubota, Risa| Bekku, Kensuke| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Araki, Motoo| |
| 抄録 | Although partial nephrectomy (PN) is preferred over radical nephrectomy (RN) for preserving renal function in patients with cT1 renal cancer, its impact on cardiovascular events (CVe) remains controversial. This study aimed to compare PN and RN in regard to the occurrence of CVe, including cerebrovascular events and exacerbation of hypertension (HT). We retrospectively analyzed 418 consecutive patients who underwent PN or RN for cT1 renal cancer. Propensity score-matching analysis was used to adjust for imbalances between patients who underwent PN and RN, leaving 102 patients in each group. The 5-year probability of cumulative CVe incidence was 6% in the PN group and 12% in the RN group (p=0.03), with a median follow-up of 73.5 months. The statistical significance was retained after propensity score matching for patients without preoperative proteinuria (p=0.03). For all CVe including cerebrovascular events and exacerbation of HT analyzed, PN provided a lower probability of occurrence than RN in patients with small renal cancers. |
| キーワード | chronic kidney disease hypertension nephrectomy proteinuria |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-12 |
| 巻 | 78巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 429 |
| 終了ページ | 437 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39719315 |
| Web of Science KeyUT | 001397799300001 |
| JaLCDOI | 10.18926/AMO/67667 |
|---|---|
| フルテキストURL | 78_5_423.pdf |
| 著者 | Sakamoto, Shinya| Tabuchi, Motoyasu| Yoshimatsu, Rika| Hishida, Ai| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| 抄録 | Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia, is usually observed in children and infants, although more recently adult-onset nesidioblastosis has also been described. We present a case of nesidioblastosis in a 78-year-old man that was detected by 111In-pentetreotide single photon emission computed tomography (SPECT/CT). The patient was transferred to our hospital’s emergency department in a hypoglycemic coma. Dynamic enhanced CT could detect no lesion in the pancreas, but an 111In-pentetreotide SPECT/CT scan performed after a similar episode four weeks later showed increased focal uptake at the head of the pancreas. The results of a selective arterial calcium injection test were negative. After careful consideration and discussion among colleagues, surgical intervention was selected, and a pancreaticoduodenectomy was performed. On histology, there were elevated numbers of Langerhans islets in the pancreatic head, and the islets themselves appeared enlarged. Hypertrophic β-cells comprised the majority, but α-cells, δ-cells and pancreatic polypeptide were also detected in the islets. Based on the histopathological results and repeated hyperinsulinemic hypoglycemic crises, the patient was finally diagnosed with adult-onset nesidioblastosis. He had no hypoglycemic symptoms during outpatient follow-up examination. Since 111In-pentetreotide SPECT/CT may be able to detect nesidioblastosis, clinicians should consider this relatively new-modality examination when encountering such cases. |
| キーワード | 111In-pentetreotide nesidioblastosis single-photon emission computed tomography hyperinsulinemic hypoglycemia |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 423 |
| 終了ページ | 428 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467661 |
| Web of Science KeyUT | 001343346400009 |
| JaLCDOI | 10.18926/AMO/67666 |
|---|---|
| フルテキストURL | 78_5_413.pdf |
| 著者 | Kashihara, Kenichi| Irisawa, Minoru| Takao, Wataru| |
| 抄録 | We investigated patients with migraine or migraine variants who exhibited focal cerebral hypoperfusion on arterial spin-labeled (ASL) magnetic resonance (MR) imaging along with neurological symptoms. Fourteen patients with migraine demonstrated focal cerebral hypoperfusion. Three other patients did not have a history of recurrent headaches but exhibited comparable cerebral hypoperfusion to migraine patients on ASL-MRI in addition to neurological symptoms. Patients with migraine may present with neurological symptoms associated with cortical spreading depression during, after, or even without a headache phase. Additionally, the isolated neurological symptoms may be caused by a pathophysiology identical to that of migraine but without presenting with recurrent headaches. |
| キーワード | arterial spin-labeled magnetic resonance imaging cortical spreading depression migraine complex migraine without headache vertigo |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 413 |
| 終了ページ | 421 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467660 |
| JaLCDOI | 10.18926/AMO/67665 |
|---|---|
| フルテキストURL | 78_5_407.pdf |
| 著者 | Shimoyama, Kyoko| Nakajima, Atsushi| Minari, Yoshimitsu| |
| 抄録 | Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but they have been known to cause immune-related adverse events (irAEs) by promoting T-cell activation. Neurological irAEs are rare (1%) but have a high fatality rate (11.5%). Here we report the first case of Bickerstaff brainstem encephalitis (BBE) induced by an ICI. A woman in her 60s with metastatic breast cancer was treated with atezolizumab plus nab-paclitaxel once intravenously. Eighteen days later, she lost consciousness with ophthalmoplegia and was diagnosed with a neurological irAE. She recovered consciousness immediately with the administration of intravenous immunoglobulin (IVIG) but suffered severe permanent peripheral neuropathy. Although it is just one case, this experience shows that BBE occurring as a neurological irAE of ICI cancer treatment may be associated with more severe outcomes than conventional BBE in metastatic cancer. Creating a system for multidisciplinary treatment is essential for ICI therapy. |
| キーワード | Bickerstaff brainstem encephalitis immune checkpoint inhibitor atezolizumab neurological immune-related adverse event breast cancer |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 407 |
| 終了ページ | 412 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467659 |
| Web of Science KeyUT | 001343346400007 |
| JaLCDOI | 10.18926/AMO/67664 |
|---|---|
| フルテキストURL | 78_5_401.pdf |
| 著者 | Toyota, Yusuke| Uda, Kazuhiro| Shirabe, Komei| Moriwake, Tadashi| |
| 抄録 | Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas. |
| キーワード | child tick-borne disease severe febrile thrombocytopenia syndrome zoonoses |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 401 |
| 終了ページ | 405 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467658 |
| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| フルテキストURL | 78_5_387.pdf |
| 著者 | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| 抄録 | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| キーワード | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 387 |
| 終了ページ | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467657 |
| Web of Science KeyUT | 001343346400005 |
| JaLCDOI | 10.18926/AMO/67662 |
|---|---|
| フルテキストURL | 78_5_377.pdf |
| 著者 | Hirano, Yuichi| Nouso, Kazuhiro| Kariyama, Kazuya| Hiraoka, Atsushi| Shiota, Shohei| Wakuta, Akiko| Yasuda, Satoshi| Toyoda, Hidenori| Tsuji, Kunihiko| Hatanaka, Takeshi| Kakizaki, Satoru| Naganuma, Atsushi| Tada, Toshifumi| Itobayashi, Ei| Ishikawa, Toru| Shimada, Noritomo| Takaguchi, Koichi| Tsutsui, Akemi| Nagano, Takuya| Imai, Michitaka| Nakamura, Shinichiro| Kumada, Takashi| Real-Life Practice Experts for HCC (RELPEC) Study Group in Japan| |
| 抄録 | We previously found that “albumin grade”, formerly called the “ALBS grade,” demonstrated significant capability for prognostic stratification in hepatocellular carcinoma (HCC) patients treated with lenvatinib. The purpose of the present study was to compare the performance of the albumin grade with that of the modified albumin-bilirubin (mALBI) grade in predicting overall survival of HCC patients with different BCLC stages and treatment types. We enrolled 7,645 Japanese patients newly diagnosed with HCC using the Akaike information criteria (AIC), likelihood ratio, and C-index in different Barcelona Clinic Liver Cancer (BCLC) stages and treatments. The albumin grade showed similar and slightly better performance than the mALBI grade for BCLC stage 0 and A and especially for patients who underwent curative surgery and ablation. In patients treated with transcatheter arterial chemoembolization, molecular targeted agents, and the best supportive care, the mALBI grade had better performance than the albumin grade. However, the differences of the indices were very small in all scenarios. Overall, the albumin grade was comparable in efficacy to the mALBI grade, showing particular benefit for patients with early-stage HCC. |
| キーワード | albumin grade hepatocellular carcinoma modified albumin-bilirubin grade |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 377 |
| 終了ページ | 386 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467656 |
| Web of Science KeyUT | 001343346400004 |
| JaLCDOI | 10.18926/AMO/67657 |
|---|---|
| フルテキストURL | 78_5_371.pdf |
| 著者 | Gotoh, Kazuyoshi| Miyoshi, Makoto| I Putu Bayu Mayura| Tsuji, Shuma| Iio, Koji| Fukushima, Shinnosuke| Matsushita, Osamu| Hagiya, Hideharu| |
| 抄録 | Spread of carbapenemase-producing Enterobacterales (CPE) is an ongoing public health issue worldwide, including in Japan. In this study, we investigated the phenotypic and genetic characteristics of CPE isolates at Okayama University Hospital over the 5 years (2013-2018) prior to the outbreak of the 2019 coronavirus pandemic. Of 24 carbapenem-resistant Enterobacterales isolated during the study period, we identified 8 CPE isolates harboring blaIMP-1 (5 isolates) and blaIMP-6 genes (3 isolates). Bacterial species and carbapenem susceptibility patterns exhibited diversity. Minimum inhibitory concentrations (MICs) of meropenem were generally higher than those of imipenem and biapenem. Results of pulsed-field gel electrophoresis demonstrated that neither clonal nor plasmid-mediated outbreaks of blaIMP-harboring CPE isolates have developed at our hospital. One Klebsiella oxytoca isolate showed a high MIC (128 μg/mL) of meropenem, which could be explained by the high plasmid copy number. Subsequent analysis of this isolate may elucidate the intricacies of carbapenem resistance profiles among CPE isolates. Collectively, our findings underscore the necessity for ongoing genetic surveillance of CPE, complemented by tailored approaches for infection prevention and control. |
| キーワード | antimicrobial resistance carbapenemase-producing enterobacterales carbapenemase-resistant enterobacterales Silent pandemic whole genome sequence |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 371 |
| 終了ページ | 376 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467655 |
| Web of Science KeyUT | 001343346400003 |
| JaLCDOI | 10.18926/AMO/67656 |
|---|---|
| フルテキストURL | 78_5_363.pdf |
| 著者 | Takanaga, Satoe| Matsumoto, Naomi| Kadowaki, Tomoka| Takao, Soshi| Yorifuji, Takashi| |
| 抄録 | Kawasaki disease (KD) is a pediatric disease of unknown etiology that commonly affects infants in East Asia. Infants born small for gestational age (SGA) have weaker immune systems and are more susceptible to infection. Using data from a nationwide Japanese birth cohort study conducted in 2010 (n=34,579), we investigated whether SGA increases the risk of KD. SGA was defined as birth weight below the 10th percentile for gestational age. The outcome was hospitalization for KD between 6 and 30 months of age. The association between SGA and hospitalization for KD, adjusted for child and maternal factors, was examined using logistic regression. Of the 231 children hospitalized for KD, 9.5% were SGA. Further statistical analysis showed that SGA did not increase the odds ratio (OR) of hospitalization for KD (adjusted OR 1.12, 95% confidence interval 0.71-1.75). This result was not changed with stratification by early daycare attendance and preterm status. Reasons for the lack of association may include the multifactorial pathogenesis of KD; in addition, the types of infections to which SGA infants are predisposed may differ from those triggering KD. Overall, our large nationwide study found no association between SGA and KD. |
| キーワード | Kawasaki disease (KD) small for gestational age (SGA) cohort epidemiology |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 363 |
| 終了ページ | 370 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467654 |
| JaLCDOI | 10.18926/AMO/67655 |
|---|---|
| フルテキストURL | 78_5_357.pdf |
| 著者 | Yamawaki, Ryoko| Oda, Yoshiaki| Yamane, Shuhei| Uotani, Koji| Misawa, Haruo| Katayama, Yoshimi| Hamada, Masanori| Ozaki, Toshifumi| |
| 抄録 | Research on postural control in patients with adolescent idiopathic scoliosis (AIS) has focused on static postural control, with few studies assessing dynamic postural control. We aimed to identify factors affecting index of postural stability (IPS), a dynamic postural control parameter, in patients with AIS. The participants comprised 50 female patients with AIS. We measured the IPS using stabilometry to evaluate dynamic postural control ability. We investigated age of the participants, major curve position (thoracic or thoracolumbar/lumbar), Cobb angle, and coronal balance. We then assessed the relationships between stabilometry parameters and other variables. IPS was analyzed with a linear regression model. Coronal balance, major curve position, and age each correlated with dynamic postural control ability. The Cobb angle showed no correlation with any of the parameters. Our results offer new insights into the assessment of postural control in patients with AIS. |
| キーワード | adolescent idiopathic scoliosis postural control coronal balance index of postural stability stabilometry |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 357 |
| 終了ページ | 362 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467653 |
| Web of Science KeyUT | 001343346400001 |
| JaLCDOI | 10.18926/AMO/67554 |
|---|---|
| フルテキストURL | 78_4_349.pdf |
| 著者 | Tominaga, Yuichiro| Sugaya, Akiko| Kariya, Shin| Shimizu, Aiko| Kataoka, Yuko| Ando, Mizuo| |
| 抄録 | Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment. |
| キーワード | middle-ear salivary gland choristoma middle-ear morphological abnormalities newborn hearing screening unilateral hearing loss surgical resection |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 349 |
| 終了ページ | 355 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198990 |
| Web of Science KeyUT | 001310557400004 |
| JaLCDOI | 10.18926/AMO/67553 |
|---|---|
| フルテキストURL | 78_4_345.pdf |
| 著者 | Kato, Gentaro| Narumiya, Yuto| Okuyama, Michihiro| Shimizu, Shuji| Sangawa, Kenji| Yamamoto, Shu| |
| 抄録 | The presence of an intraperitoneal source of infection, e.g., a liver abscess, can be an obstacle to performing an abdominal aortic surgery with a midline laparotomy because graft infection is one of the most critical complications of aortic surgery. We report the successful Y-grafting of a pararenal abdominal aortic aneurysm through a retroperitoneal approach in a 67-year-old male undergoing liver abscess drainage. The retroperitoneal approach to the abdominal aorta may be useful for abdominal aortic surgery in patients with a localized intraperitoneal infection. |
| キーワード | blunt liver trauma liver abscess abdominal aortic aneurysm Y-grafting retroperitoneal approach |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 345 |
| 終了ページ | 347 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198989 |
| Web of Science KeyUT | 001310557400003 |
| JaLCDOI | 10.18926/AMO/67550 |
|---|---|
| フルテキストURL | 78_4_337.pdf |
| 著者 | Makihara, Seiichiro| Otani, Yoshihiro| Uraguchi, Kensuke| Ono, Sawako| Shimizu, Aiko| Ikemachi, Ryosuke| Okazaki, Yosuke| Ota, Tomoyuki| Matsumoto, Hiroshi| Miyamoto, Shotaro| Tsumura, Munechika| Hayashi, Seiya| Umakoshi, Michiari| Hirashita, Koji| Ando, Mizuo| |
| 抄録 | Here, we describe the unique case of a pneumocephalus originating from an inverted papilloma (IP) in the frontoethmoidal sinus. A 71-year-old man with diabetes presented with headaches and altered consciousness. Imaging revealed the pneumocephalus together with bone destruction in the left frontal sinus. He underwent simultaneous endoscopic endonasal and transcranial surgery using an ORBEYE exoscope. Pathological diagnosis of the tumor confirmed IP. Post-surgery, the pneumocephalus was significantly resolved and the squamous cell carcinoma antigen level, which had been elevated, decreased. This case underscores the importance of a multidisciplinary approach and innovative surgical methods in treating complex sinonasal pathologies. |
| キーワード | pneumocephalus inverted papilloma frontoethmoidal sinus endoscopic endonasal and transcranial surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 337 |
| 終了ページ | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198988 |
| Web of Science KeyUT | 001310557400002 |
| JaLCDOI | 10.18926/AMO/67549 |
|---|---|
| フルテキストURL | 78_4_331.pdf |
| 著者 | Furukawa, Chieko| Tachibana, Tomoyasu| Nobuhisa, Tetsuji| Kanie, Yuichiro| Wani, Yoji| Matsumoto, Jun-Ya| Kariya, Akifumi| Sato, Asuka| Ishikawa, Iichiro| Naoi, Yuto| Ando, Mizuo| |
| 抄録 | No previous study has published magnetic resonance imaging (MRI) findings for a subglottic pleomorphic adenoma. Here, we describe the case of a 62-year-old man with a subglottic pleomorphic adenoma. Endoscopic findings revealed a smooth-surfaced tumor arising from the subglottic posterior wall. MRI revealed the lesion as an isointense region on T1-weighted images, which was homogeneously enhanced. This lesion showed a heterogeneously hyperintense region on T2-weighted images. Diffusion-weighted imaging (DWI) showed slightly high intensity in the same area, with a normal or only slightly high apparent diffusion coefficient (ADC). Laryngomicrosurgery was performed for transoral excision of the subglottic tumor, resulting in a postsurgical diagnosis of pleomorphic adenoma. |
| キーワード | subglottis pleomorphic adenoma MRI transoral surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 331 |
| 終了ページ | 335 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198987 |
| Web of Science KeyUT | 001310557400001 |
| JaLCDOI | 10.18926/AMO/67548 |
|---|---|
| フルテキストURL | 78_4_323.pdf |
| 著者 | Katayama, Akira| Kimura, Satoshi| Matsusaki, Takashi| Morimatsu, Hiroshi| |
| 抄録 | It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications. |
| キーワード | pediatric liver transplantation postoperative severe complications Graft-to-Recipient Weight Ratio |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 323 |
| 終了ページ | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198986 |
| Web of Science KeyUT | 001310576400003 |
| JaLCDOI | 10.18926/AMO/67547 |
|---|---|
| フルテキストURL | 78_4_313.pdf |
| 著者 | Eto, Eriko| Maki, Jota| Yamashita, Noriyuki| Hasegawa, Toru| Suemori, Ayano| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Kirino, Satoe| Ohira, Akiko| Masuyama, Hisashi| |
| 抄録 | During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku–Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable. |
| キーワード | remote simulator education perinatal simulator information and communication technology high-flexibility education |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 313 |
| 終了ページ | 322 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198985 |
| Web of Science KeyUT | 001310576400002 |
| JaLCDOI | 10.18926/AMO/67546 |
|---|---|
| フルテキストURL | 78_4_307.pdf |
| 著者 | Sugihara, Naoya| Hashine, Katsuyoshi| Yamashita, Natsumi| Sakamoto, Miki| Terashita, Masato| Funaki, Keisuke| Saiki, Kaori| Sawada, Takatora| Kakuda, Toshio| Nishimura, Kenichi| Fukumoto, Tetsuya| Miura, Noriyosi| Miyauchi, Yuki| Kikugawa, Tadahiko| Saika, Takashi| |
| 抄録 | The Briganti nomogram (cut-off value 5%) is commonly used to determine the indications for pelvic lymph node dissection (PLND) in patients with prostate cancer. We retrospectively analyzed the potential oncological benefit of PLND based on the 5% cut-off value on the Briganti nomogram. We obtained the data from the Medical Investigation Cancer Network (MICAN) Study, which included 3,463 patients who underwent a radical prostatectomy (RP) at nine institutions in Japan between 2010 and 2020. We included patients with Briganti scores ≥ 5% and a follow-up period ≥6 months and excluded patients categorized in the very high-risk group (based on NCCN categories); a final total of the cases of 1,068 patients were analyzed. The biochemical recurrence (BCR)-free survival was significantly worse in the patients who underwent PLND compared to those who did not (p=0.019). A multivariate analysis showed that high prostate-specific antigen (PSA) levels (p<0.001) and an advanced T-stage (p=0.018) were significant prognostic factors for BCR, whereas PLND had no effect on BCR (p=0.059). Thus, PLND in patients with prostate cancer whose Briganti score was 5% did not provide any oncological benefit. Further research is necessary to determine the indication criteria for conducting PLND. |
| キーワード | Briganti nomogram pelvic lymph node dissection prostate cancer radical prostatectomy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-08 |
| 巻 | 78巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 307 |
| 終了ページ | 312 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39198984 |
| Web of Science KeyUT | 001310576400001 |
| JaLCDOI | 10.18926/AMO/67207 |
|---|---|
| フルテキストURL | 78_3_301.pdf |
| 著者 | Nakazaki, Kiyoshi| Hirai, Satoshi| Hishikawa, Tomohito| |
| 抄録 | We report a case of a large vestibular schwannoma in an 80-year-old female patient that shrank after palliative Gamma Knife radiosurgery (GKS). Neurological symptoms included hearing deterioration and facial palsy. The tumor volume was 21.9 mL. Craniotomy was considered high-risk, and conventional GKS was risky, owing to the risk of transient enlargement. Therefore, GKS was performed on only a portion of the tumor. The marginal dose (12 Gy) volume was 3.8 mL (17.4%). The tumor began to shrink after transient enlargement. Sixty months later, the tumor volume was only 3.1 mL, and the patient was able to maintain independent activities of daily living without salvage treatment. |
| キーワード | vestibular schwannoma Gamma Knife radiosurgery large volume palliative elderly patient |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-06 |
| 巻 | 78巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 301 |
| 終了ページ | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38902220 |
| Web of Science KeyUT | 001267340600001 |
| JaLCDOI | 10.18926/AMO/67206 |
|---|---|
| フルテキストURL | 78_3_295.pdf |
| 著者 | Okamoto, Sara| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Kanzaki, Yuki| Kindo, Hiroya| Morita, Tetsuro| Tsuji, Akihiro| Takahashi, Kosuke| Morizane, Yuki| |
| 抄録 | A Japanese woman in her 70s was referred to our hospital for the evaluation and treatment of high intraocular pressure (IOP) in her right eye. She had undergone bilateral cataract surgeries and the insertion of hydrophilic acrylic intraocular lenses (IOLs). We performed trabeculotomy and trabeculectomy to lower her right IOP; thereafter, a circular opacity was observed on the right eye’s IOL surface. We removed the right IOL because that eye’s vision had decreased due to IOL opacification. The analysis of the removed IOL revealed that the main opacity component was calcium phosphate. This is the first post-glaucoma-surgery IOL calcification case report. |
| キーワード | intraocular lens IOL IOL calcification hydrophilic acrylic IOL glaucoma surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-06 |
| 巻 | 78巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 295 |
| 終了ページ | 300 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38902219 |
| Web of Science KeyUT | 001267339400001 |