ID | 31098 |
JaLCDOI | |
フルテキストURL | |
著者 |
Takahashi, Michiko
Okayama University
Yamada, Gotaro
Okayama University
Doi, Toshihiko
Okayama Univeristy
Takatani, Masahiro
Okayama University
Kishi, Fumitoshi
Okayama University
Miyamoto, Rieko
Okayama University
Yoshizawa, Hiroshi
Hiroshima University
Okamoto, Hiroaki
Jichi Medical School
Tsuji, Takao
Jichi Medical School
|
抄録 | Hepatitis C virus (HCV)-RNA in the blood was measured by polymerase chain reaction (PCR) in 37 subjects from eight families in which 2 or more persons tested seropositive for antibodies against C100-3 or CP9. HCV-RNA was positive in 17 of 37 subjects. Two or more HCV-RNA-positive subjects were observed in six of the families. Intrafamilial HCV infection was studied by determining the HCV-RNA type (I, II, III or IV) by PCR using type-specific primers. In two families, all of the subjects showed type III infection, and in three other families, all of the subjects showed type II infection, with different types of HCV infections being observed in only one family. The HCV type was uniform in all but one. These findings suggest a possibility of intrafamilial infection between husbands and wives and between members of the same household. |
キーワード | HCV
intrafamilial transmission
HCV-RNA genotype
|
Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1994-12
|
巻 | 48巻
|
号 | 6号
|
出版者 | Okayama University Medical School
|
開始ページ | 293
|
終了ページ | 297
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
|
PubMed ID | |
Web of Science KeyUT |