ID | 31093 |
JaLCDOI | |
フルテキストURL | |
著者 |
Masuda, Shusaku
Kochi Medical School
Watanabe, Hironobu
Kochi Medical School
Morioka, Masaaki
Kochi Medical School
Fujita, Yukitoshi
Kochi Medical School
Ageta, Tomiko
Kochi Medical School
Kodama, Hiroyuki
Kochi Medical School
|
抄録 | Both prolidase and prolinase from the human prostate were separated into two peaks by TSK DEAE-5PW chromatography. These peaks of prolidase isozymes I and II differed from each other in their responses to preincubation with Mn2+, their substrate specificity, optimal pH, and heat stability. The molecular weights of prolidases I and II were estimated to be 110,000 and 165,000, respectively, by gel filtration. Substrate specificity of prolinase peaks I and II was almost the same, but they differed in optimal pH and heat stability. The molecular weights of prolinases I and II were about 85,000 and 63,000, respectively. These results indicate that two isozymes of prolidase and of prolinase, which differ in various characteristics, are present in the human prostate. |
キーワード | human prostate
prolidase
prolinase
|
Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1994-08
|
巻 | 48巻
|
号 | 4号
|
出版者 | Okayama University Medical School
|
開始ページ | 173
|
終了ページ | 179
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
|
PubMed ID | |
Web of Science KeyUT |