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ID 54592
JaLCDOI
フルテキストURL
70_5_345.pdf 2.12 MB
著者
Maruyama, Hidehiko Department of Pediatrics, Kochi Health Sciences Center
Nakata, Yusei Department of Pediatrics, Kochi Health Sciences Center
Kanazawa, Akane Department of Pediatrics, Kochi Health Sciences Center
Kikkawa, Kiyoshi Department of Pediatrics, Kochi Health Sciences Center
抄録
We sought to clarify the survival and neurodevelopmental outcomes of very low birth weight infants (VLBWIs) and to identify risk factors for death or neurodevelopmental impairment (NDI) in VLBWIs at our hospital. The total study population was 217 infants born in 2005-2012 weighing ≤1,500 g. We compared their outcomes with those from previous reports analyzed the causes of death. Risk factors for death after discharge or NDI were evaluated by a multivariate logistic regression analysis. The incidences of death or NDI reported revealed in this study and the database of Neonatal Research Network of Japan were 25.3% and 19.6% (p=0.039), respectively. The main causes of death before discharge were intraventricular hemorrhage, sepsis, and persistent pulmonary hypertension of the newborn. The significant risk factors for death after discharge or NDI were early gestational age (weeks) and periventricular leukomalacia (adjusted odds ratio [95% confidence interval, p-value], 0.72 [0.54-0.94, 0.017] and 6.90 [1.35-38.25, 0.021], respectively). These factors must be addressed in order to improve treatment strategies for VLBWIs.
キーワード
intraventricular hemorrhage
periventricular leukomalacia
persistent pulmonary hypertension of the newborn
sepsis
very low birth weight infants
Amo Type
Original Articles
出版物タイトル
Acta Medica Okayama
発行日
2016-10
70巻
5号
出版者
Okayama University Medical School
開始ページ
345
終了ページ
352
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
英語
著作権者
CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT