ID | 32774 |
JaLCDOI | |
フルテキストURL | |
著者 |
Kashihara, Eiji
Okayama University
|
抄録 | MC-induced sarcomas produced under the skin on the back between scapulas of C3H mice were transplanted successively to the mice of the same strain. Using the first and the second generation tumors, viable tumor cells were prepared and with these tumor cells C3H mice were inoculated. From these sensitized mice regional lymph nodes were taken out at certain intervals and lymph-node cells were prepared. These tumor cells were mixed with regional lymph-node cells in the ratio of 1 : 10, and the mixed cells were transplanted subcutaneously on the back of C3H mice, and the development and growth of tumors were observed at intervals. As a result it was found that the inhibitory effect of these regional lymph-node cells on the tumor growth was strong one to two weeks after the transplantation, but beyond 3, or 4 weeks no inhibition was observable. In connection with the present in vivo experiments, some comments were made on the available literature, and it has been demonstrated that even in the cancer-bearing animal destined to die of tumors, at certain stage of cancer there is seen an inhibitory effect of the host on the tumor growth by way of the lymphoid system and that such a response of the host in vivo seems to be correlated well with in vitro reaction. |
Amo Type | Article
|
出版物タイトル |
Acta Medicinae Okayama
|
発行日 | 1970-04
|
巻 | 24巻
|
号 | 2号
|
出版者 | Okayama University Medical School
|
開始ページ | 161
|
終了ページ | 173
|
NCID | AA00041342
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
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PubMed ID | |
NAID |