ID | 32466 |
JaLCDOI | |
フルテキストURL | |
著者 |
Hiraki, Kiyoshi
Okayama University
Kimura, Ikuro
Okayama University
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抄録 | Eleven cases of malignant lymphomas were treated with a fibroblast-inhibiting agent, chloroquine, and of these, one case of lymphosarcoma, two of acute and chronic lymphocytic leukemia, respectively, and two of giant follicle lymphoma showed regression of the enlarged lymph nodes and also of the enlarged spleen in some of the splenomegalic patients. In contrast, the drug proved ineffective in two cases of reticulum cell sarcoma and Hodgkin's disease, respectively. The side effects of the drug were minimal, and three of the 11 cases complained of nausea, anorexia or palpebral ptosis, which disappeared by decreasing the drug dosage or combining ATP preparation. The tissue culture study of biopsied lymph nodes from lymphocytic leukemia showed inhibition of the growth zone in a medium containing chloroquine indicating a possibility of the drug action not only upon the stromal tissue but also upon the parenchymal tumor cell. |
Amo Type | Article
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出版物タイトル |
Acta Medicinae Okayama
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発行日 | 1964-04
|
巻 | 18巻
|
号 | 2号
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出版者 | Okayama University Medical School
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開始ページ | 87
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終了ページ | 92
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NCID | AA00041342
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資料タイプ |
学術雑誌論文
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言語 |
英語
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
NAID |