ID | 60800 |
JaLCDOI | |
フルテキストURL | |
著者 |
Togo, Masaaki
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
Akazawa, Yuko
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
Akashi, Taro
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
Yamashita, Rika
Oral Care Center, Nagasaki University Hospital
Yoshitomi, Izumi
JCHO Isahaya General Hospital
Ohba, Kazuo
JCHO Isahaya General Hospital
Hashimoto, Satsuki
JCHO Isahaya General Hospital
Iwashita, Hiroko
JCHO Isahaya General Hospital
Kurogi, Tadafumi
Oral Care Center, Nagasaki University Hospital
Osada, Yukiko
Dental Hygienist's Office, Department of Medical Technology, Nagasaki University Hospital
Wada, Noriko
Dental Hygienist's Office, Department of Medical Technology, Nagasaki University Hospital
Imamura, Yoshifumi
Department of Respiratory Medicine, Nagasaki University Hospital
Hashiguchi, Keiichi
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
Yamaguchi, Naoyuki
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
Kondo, Hisayoshi
Biostatistics Section, Division of Scientific Data Registry, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Medicine
Nakao, Kazuhiko
Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
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抄録 | Endoscopic submucosal dissection (ESD) has become the first-line treatment for early gastric neoplasms; however, a subset of patients treated by this method develop aspiration pneumonia. We conducted a comprehensive prospective analysis of the factors contributing to post-ESD aspiration pneumonia in early gastric neoplasms in this study, with special focus on whether pre-treatment oral care can prevent aspiration pneumonia. Sixty-one patients who underwent ESD for gastric neoplasms were randomly assigned to the oral care or control groups. ESD was performed under deep sedation. Of 60 patients whose data were available for analysis, 5 (8.3%) experienced pneumonia confirmed either by chest radiography or computed tomography. Although no difference in the rate of pneumonia was found between the control and oral care groups, the post-oral care bacteria count was significantly higher in the saliva of patients who developed pneumonia compared to those without pneumonia. In addition, the presence of vascular brain diseases and the dose of meperidine were also significantly associated with the occurrence of pneumonia. These results suggest that the number of oral bacteria as well as pre-existing vascular brain diseases and high-dose narcotics can affect the incidence of post-ESD pneumonia.
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キーワード | endoscopy
oral bacteria
respiratory disease
pneumonia
sedation
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2020-10
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巻 | 74巻
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号 | 5号
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出版者 | Okayama University Medical School
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開始ページ | 407
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終了ページ | 413
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2020 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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NAID |