ID | 59948 |
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フルテキストURL | |
著者 |
Sano, Toshikazu
Department of Surgery, Division of Pediatric Cardiothoracic Surgery, University of California San Francisco
Ishigami, Shuta
Department of Surgery, Division of Pediatric Cardiothoracic Surgery, University of California San Francisco
Ito, Tatsuo
Department of Hygiene, Kawasaki Medical University
Sano, Shunji
Department of Surgery, Division of Pediatric Cardiothoracic Surgery, University of California San Francisco
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抄録 | Heart diseases are one of the major causes of morbidity and mortality worldwide. Despite major advances in drug and interventional therapies, surgical procedures, and organ transplantation, further research into new therapeutic options is still necessary. Stem cell therapy has emerged as one option for the treatment of a variety of heart diseases. Although a large number of clinical trials have shown stem cell therapy to be a promising therapeutic approach, the results obtained from these clinical studies are inconsistent, and stem cell-based improvements of heart performance and cardiac remodeling were found to be quite limited. Since the precise mechanisms underlying the therapeutic actions of stem cells are still under debate, researchers have developed a variety of strategies to improve and boost the potency of stem cells in repair. In this review, we summarize both the current therapeutic strategies using stem cells and future directions for enhancing stem cell potency.
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キーワード | heart disease
stem cell
myocardial regeneration
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Amo Type | Review
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2020-06
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巻 | 74巻
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号 | 3号
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出版者 | Okayama University Medical School
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開始ページ | 185
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終了ページ | 190
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2020 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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