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ID 59973
フルテキストURL
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著者
Iwamuro, Masaya Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID researchmap
Miyahara, Koji Department of Internal Medicine, Hiroshima City Hospital
Sakaguchi, Chihiro Department of Endoscopy, National Hospital Organization Shikoku Cancer Center
Takenaka, Ryuta Department of Internal Medicine, Tsuyama Chuo Hospital
Kobayashi, Sayo Department of Internal Medicine, Fukuyama City Hospital
Mouri, Hirokazu Department of Gastroenterology and Hepatology, Kurashiki Central Hospital
Tanaka, Shigetomi Department of Gastroenterology, Kagawa Prefectural Central Hospital
Toyokawa, Tatsuya Department of Gastroenterology, Fukuyama Medical Center
Tanaka, Shouichi Department of Gastroenterology, Iwakuni Clinical Center
Nishimura, Mamoru Department of Internal Medicine, Okayama City Hospital
Yamauchi, Kenji Department of Gastroenterology, Mitoyo General Hospital
Tanaka, Takehiro Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Kaken ID
Okada, Hiroyuki Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID publons researchmap
抄録
There have been no comparative studies investigating the results of 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) in patients with gastric mesenchymal tumors, including leiomyomas, leiomyosarcomas, schwannomas, and gastrointestinal stromal tumors (GISTs). We retrospectively reviewed the data of 142 patients with pathologically diagnosed gastric mesenchymal tumors treated at 11 institutions. We analyzed the correlation between the maximum standardized uptake value (SUVmax) evaluated using fluorodeoxyglucose-positron emission tomography (FDG-PET) and the tumor size. The correlation between the SUVmax and mitotic index was also investigated in GISTs. The SUVmax (mean +/- standard deviation) was 0.5 +/- 0.6 in very low-risk GISTs (n = 42), 2.1 +/- 0.7 in low-risk GISTs (n = 26), 4.9 +/- 0.8 in intermediate-risk GISTs (n = 22), 12.3 +/- 0.8 in high-risk GISTs (n = 20), 1.0 +/- 1.0 in leiomyomas (n = 15), 6.9 +/- 1.2 in schwannomas (n = 10), and 3.5 in a leiomyosarcoma (n = 1). The SUVmax of GISTs with an undetermined risk classification was 4.2 +/- 1.3 (n = 8). Linear associations were observed between the SUVmax and tumor size in GISTs, leiomyomas, and schwannomas. The SUVmax of GISTs with a high mitotic index was significantly higher than that of GISTs with a low mitotic index (9.6 +/- 7.6 vs. 2.4 +/- 4.2). In conclusion, we observed positive correlations between the SUVmax and tumor size in GISTs, leiomyomas, and schwannomas. The SUVmax also positively correlated with the mitotic index and risk grade in GISTs. Schwannomas showed a higher FDG uptake than GISTs and leiomyomas.
キーワード
18F-fluorodeoxyglucose-positron emission tomography
mesenchymal tumor
gastric neoplasms
gastrointestinal stromal tumor
schwannoma
発行日
2020-05-01
出版物タイトル
Journal of Clinical Medicine
9巻
5号
出版者
MDPI
開始ページ
1301
ISSN
2077-0383
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
著作権者
© 2020 by the authors.
論文のバージョン
publisher
PubMed ID
DOI
Web of Science KeyUT
関連URL
isVersionOf https://doi.org/10.3390/jcm9051301
ライセンス
http://creativecommons.org/licenses/by/4.0/