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ID 50687
フルテキストURL
著者
Asagi, Akinori Shikoku Canc Ctr, Dept Gastroenterol
Ohta, Koji Shikoku Canc Ctr, Dept Surg Gastroenterol
Nasu, Junichirou Shikoku Canc Ctr, Dept Gastroenterol
Tanada, Minoru Shikoku Canc Ctr, Dept Surg Gastroenterol
Nadano, Seijin Shikoku Canc Ctr, Dept Gastroenterol
Nishimura, Rieko Shikoku Canc Ctr, Dept Pathol
Teramoto, Norihiro Shikoku Canc Ctr, Dept Pathol
Yamamoto, Kazuhide Okayama Univ, Grad Sch Med, Dept Gastroenterol & Hepatol
Inoue, Takeshi Shikoku Canc Ctr, Dept Diagnost Radiol
Iguchi, Haruo Shikoku Canc Ctr, Dept Gastroenterol
抄録
Objectives: Fluorodeoxyglucose (FDG)-positron emission tomography/contrast-enhanced computed tomography (PET/CE-CT) involving whole-body scanning first by non-CE-CT and FDG-PET followed by CE-CT has been used for detailed examination of pancreatic lesions. We evaluated PET/CE-CT images with regard to differential diagnosis, staging, treatment response, and postoperative recurrence in pancreatic cancer. Methods: Positron emission tomography/CE-CT was conducted in 108 patients with pancreatic cancer and in 41 patients with other pancreatic tumor diseases. Results: The maximum standardized uptake value (SUVmax) overlapped in benign and malignant cases, suggesting that differential diagnosis of pancreatic tumors based on the SUVmax is difficult. In the evaluation of staging in 31 resectable pancreatic cancer by PET/CE-CT, the diagnostic accuracy rate was more than 80% for most factors concerning local invasion and 94% for distant metastasis but only 42% for lymph node metastasis. Significant positive correlations were found between the SUVmax and tumor size/markers, suggesting that SUVmax may be a useful indicator for the treatment response. Regarding the diagnosis of the postoperative recurrence, PET/CE-CT correctly detected local recurrence in all the 11 cases of recurrence, whereas abdominal CE-CT detected only 7 of 11 cases, suggesting that PET/CE-CT is superior in this context. Conclusions: Positron emission tomography/CE-CT is useful for the clinical management of pancreatic cancer.
キーワード
contrast-enhanced PET/CT
differential diagnosis
clinical management
pancreatic cancer
発行日
2013-01
出版物タイトル
Pancreas
42巻
1号
出版者
Lippincott Williams & Wilkins
開始ページ
11
終了ページ
19
ISSN
0885-3177
資料タイプ
学術雑誌論文
オフィシャル URL
http://dx.doi.org/10.1097/MPA.0b013e3182550d77
関連URL
http://ousar.lib.okayama-u.ac.jp/metadata/50660
言語
English
論文のバージョン
author
査読
有り
DOI
Web of Sience KeyUT