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ID 48711
フルテキストURL
著者
Kataoka, Takahiro Graduate School of Health Sciences, Okayama University
Yamaoka, Kiyonori Graduate School of Health Sciences, Okayama University
抄録
Adequate oxygen stress induced by low-dose irradiation activates biodefense system, such as induction of the synthesis of superoxide dismutase (SOD) and glutathione peroxidase. We studied the possibility for alleviation of oxidative damage, such as diabetes and nonalcoholic liver disease. Results show that low-dose γ-irradiation increases SOD activity and protects against alloxan diabetes. Prior or post-low-dose X- or γ-irradiation increases antioxidative functions in livers and inhibits ferric nitrilotriacetate and carbon tetrachloride-induced (CCl4) hepatopathy. Moreover, radon inhalation also inhibits CCl4-induced hepatopathy. It is highly possible that low-dose irradiation including radon inhalation activates the biodefence systems and, therefore, contributes to preventing or reducing reactive oxygen species-related diabetes and nonalcoholic liver disease, which are thought to involve peroxidation.
発行日
2012-02-09
出版物タイトル
ISRN Endocrinology
2012巻
出版者
Hindawi Publishing Corporation
開始ページ
11
終了ページ
11
資料タイプ
学術雑誌論文
オフィシャル URL
http://www.isrn.com/journals/endocrinology/2012/292041/
言語
English
OAI-PMH Set
岡山大学
著作権者
Copyright © 2012 T. Kataoka and K. Yamaoka
論文のバージョン
publisher
査読
有り
DOI