ID | 48711 |
フルテキストURL | |
著者 |
Kataoka, Takahiro
Graduate School of Health Sciences, Okayama University
ORCID
Kaken ID
publons
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Yamaoka, Kiyonori
Graduate School of Health Sciences, Okayama University
Kaken ID
publons
researchmap
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抄録 | Adequate oxygen stress induced by low-dose irradiation activates biodefense system, such as induction of the synthesis of superoxide dismutase (SOD) and glutathione peroxidase. We studied the possibility for alleviation of oxidative damage, such as diabetes and nonalcoholic liver disease. Results show that low-dose γ-irradiation increases SOD activity and protects against alloxan diabetes. Prior or post-low-dose X- or γ-irradiation increases antioxidative functions in livers and inhibits ferric nitrilotriacetate and carbon tetrachloride-induced (CCl4) hepatopathy. Moreover, radon inhalation also inhibits CCl4-induced hepatopathy. It is highly possible that low-dose irradiation including radon inhalation activates the biodefence systems and, therefore, contributes to preventing or reducing reactive oxygen species-related diabetes and nonalcoholic liver disease, which are thought to involve peroxidation.
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発行日 | 2012-02-09
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出版物タイトル |
ISRN Endocrinology
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巻 | 2012巻
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出版者 | Hindawi Publishing Corporation
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開始ページ | 11
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終了ページ | 11
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資料タイプ |
学術雑誌論文
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オフィシャル URL | http://www.isrn.com/journals/endocrinology/2012/292041/
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言語 |
英語
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著作権者 | Copyright © 2012 T. Kataoka and K. Yamaoka
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論文のバージョン | publisher
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査読 |
有り
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DOI |