ID | 58737 |
フルテキストURL | |
著者 |
Takao, Miyuki
Division of Infection Control and Prevention, Osaka University Hospital
Yoshioka, Nori
Division of Infection Control and Prevention, Osaka University Hospital
Hagiya, Hideharu
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
researchmap
Deguchi, Matsuo
Division of Infection Control and Prevention, Osaka University Hospital
Kagita, Masanori
Division of Infection Control and Prevention, Osaka University Hospital
Tsukamoto, Hiroko
Laboratory for Clinical Investigation, Osaka University Hospital
Hidaka, Yoh
Laboratory for Clinical Investigation, Osaka University Hospital
Tomono, Kazunori
Division of Infection Control and Prevention, Osaka University Hospital
Tobe, Toru
Department of Biomedical Informatics, Osaka University Graduate School of Medicine
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抄録 | Background
Cytomegalovirus (CMV) are ubiquitously distributed worldwide, causing a wide range of clinical manifestations from congenital infection to a life-threatening disease in immunocompromised individuals. CMV can be transmitted via human-to-human contact through body fluids; however, the risk of CMV infection among healthcare workers (HCWs) has not been fully evaluated.
Aim
This study aimed to assess the risk of CMV infection among HCWs through daily medical practices.
Methods
Serum samples from HCWs at Osaka University Hospital (Japan) were analysed. Initially, we compared CMV IgG seropositivity among HCWs (medical doctors, nurses, and others) in 2017, which was examined after 1 year to evaluate seroconversion rates among those with seronegative results. Then, we examined CMV seroconversion rates in HCWs who were exposed to blood and body fluids.
Findings
We analysed 1153 samples of HCWs (386 medical doctors, 468 nurses, and 299 others), of which CMV seropositivity rates were not significantly different (68.9%, 70.3%, and 70.9%, respectively). Of these, 63.9% (221/346) of CMV seronegative HCWs were followed after 1 year, with CMV seroconversion rates of 3.2% (7/221). Among 72 HCWs who tested negative for CMV IgG when exposed to blood and body fluids, the CMV seroconversion rate was 2.8% (2/72). The CMV seroconversion rates between the two situations were not significantly different.
Conclusion
Our study indicated that CMV infection through daily patient care seems quite rare. Further well-designed studies with a large sample size are warranted to verify our finding.
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キーワード | Blood and body fluid exposure
Cytomegalovirus
Healthcare workers
Occupational infection
Seroconversion
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発行日 | 2020-03-10
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出版物タイトル |
Journal of Infection and Chemotherapy
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巻 | 26巻
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号 | 7号
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出版者 | Elsevier
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開始ページ | 681
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終了ページ | 684
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ISSN | 1341-321X
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NCID | AA11057978
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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論文のバージョン | author
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1016/j.jiac.2020.02.011
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ライセンス | https://creativecommons.org/licenses/by-nc-nd/4.0/
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