ID | 58717 |
フルテキストURL | |
著者 |
Katoh, Norito
Department of Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science
Ohya, Yukihiro
Allergy Center, National Center for Child Health and Development
Ikeda, Masanori
Department of Pediatric Acute Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
Kaken ID
publons
researchmap
Ebihara, Tamotsu
Department of Dermatology, Keio University School of Medicine
Katayama, Ichiro
Department of Dermatology, Graduate School of Medicine, Osaka University
Saeki, Hidehisa
Department of Dermatology, Graduate School of Medicine, Nihon Medical School
Shimojo, Naoki
Department of Pediatrics, Graduate School of Medicine, Chiba University
Tanaka, Akio
Department of Dermatology, Hiroshima University Graduate School of Biomedical Sciences
Nakahara, Takeshi
Division of Skin Surface Sensing, Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
Nagao, Mizuho
Division of Clinical Research, National Hospital Organization Mie National Hospital
Hide, Michihiro
Department of Dermatology, Hiroshima University Graduate School of Biomedical Sciences
Fujita, Yuji
Department of Pediatrics, Graduate School of Medicine, Chiba University
Fujisawa, Takao
Division of Allergy, National Hospital Organization Mie National Hospital
Futamura, Masaki
Division of Pediatrics, National Hospital Organization Nagoya Medical Center
Masuda, Koji
Department of Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science
Murota, Hiroyuki
Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
Yamamoto-Hanada, Kiwako
Allergy Center, National Center for Child Health and Development
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抄録 | Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion, which is frequently encountered in clinical practice. Skin barrier dysfunction leads to enhanced skin irritability to non-specific stimuli and epicutaneous sensitization. In the lesion site, a further inflammation-related reduction in skin barrier function, enhanced irritability and scratching-related stimuli deteriorate eczema, leading to vicious cycle of inflammation. The current strategies to treat AD in Japan from the perspective of evidence-based medicine consist of three primary measures: (i) the use of topical corticosteroids and tacrolimus ointment as the main treatment for the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling and advice about daily life. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity-related patient outcomes with respect to several important points requiring decision-making in clinical practice.
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キーワード | Atopic dermatitis
Clinical practice guidelines
Eczema
Evidence-based medicine
Treatment
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発行日 | 2020-04-04
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出版物タイトル |
Allergology International
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巻 | 69巻
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号 | 3号
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出版者 | Elsevier
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開始ページ | 356
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終了ページ | 369
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ISSN | 13238930
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NCID | AA11091750
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2020 Japanese Society of Allergology. Production and hosting by Elsevier B.V.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
関連URL | IsVersionOf 10.1016/j.alit.2020.02.006
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ライセンス | http://creativecommons.org/licenses/by-nc-nd/4.0/
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Citation | Katoh N, Ohya Y, Ikeda M, et al. Japanese guidelines for atopic dermatitis 2020 [published online ahead of print, 2020 Apr 4]. Allergol Int. 2020;S1323-8930(20)30018-6. doi:10.1016/j.alit.2020.02.006
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オープンアクセス(出版社) |
OA
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オープンアーカイブ(出版社) |
非OpenArchive
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