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ID 46938
フルテキストURL
著者
Kitamatsu, Mizuki Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Kubo, Takanori Faculty of Pharmacy, Yasuda Women’s University
Matsuzaki, Rino Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Endoh, Tamaki Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Ohtsuki, Takashi Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Sisido, Masahiko Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
抄録
A peptide nucleic acid (PNA)-cell-penetrating peptide (CPP) conjugate (carrier PNA) was used as 'bridgebuilder' to connect a CPP with an shRNA. The carrier PNA successfully formed a hybrid with an shRNA bearing complementary dangling bases and the shRNA was introduced into cells by the carrier PNA, and RNAi was induced by the shRNA.
キーワード
Peptide nucleic acid
Cell-penetrating peptide
RNA interference
発行日
2009-07-01
出版物タイトル
Bioorganic & Medicinal Chemistry Letters
19巻
13号
出版者
Elsevier Ltd.
開始ページ
3410
終了ページ
3413
ISSN
0960-894X
NCID
AA1079577X
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
著作権者
Crown Copyright © 2009 Published by Elsevier Ltd. All rights reserved.
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