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ID 65774
著者
Ono, Ryota Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Saeki, Nozomu Research Core for Interdisciplinary Sciences, Okayama University
Kojima, Keiichi Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID researchmap
Moriya, Hisao Research Core for Interdisciplinary Sciences, Okayama University ORCID Kaken ID publons researchmap
Sudo, Yuki Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID researchmap
抄録
Upon white light illumination, the growth of the budding yeast Saccharomyces cerevisiae was extremely impaired only in the presence of iodide ions, but not fluoride, chloride and bromide ions. Action spectroscopy revealed that the maximum wavelength of the light is around at 373 nm, corresponding to the UVA region. Using a genetic approach, several genes, including OPY1, HEM1, and PAU11, were identified as suppressors of this growth inhibition. This iodide-dependent UVA-triggered growth inhibition method, along with its suppressive molecules, would be beneficial for understanding cell growth processes in eukaryotes and can be utilized for medium sterilization using UVA light.
キーワード
UVA
Saccharomyces cerevisiae
Iodide
Growth inhibition
Suppressive molecule
備考
© 2023 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
This fulltext file will be available in Oct. 2024.
発行日
2023-10-15
出版物タイトル
Biochemical and Biophysical Research Communications
677巻
出版者
Elsevier BV
開始ページ
1
終了ページ
5
ISSN
0006-291X
NCID
AA00564395
資料タイプ
学術雑誌論文
言語
英語
OAI-PMH Set
岡山大学
著作権者
© 2023 Elsevier Inc.
論文のバージョン
author
PubMed ID
DOI
Web of Science KeyUT
関連URL
isVersionOf https://doi.org/10.1016/j.bbrc.2023.07.048
ライセンス
https://creativecommons.org/licenses/by-nc-nd/4.0
助成機関名
Japan Society for the Promotion of Science
助成番号
JP23H02449
JP18H02411
JP21H02446