ID | 62847 |
フルテキストURL | |
著者 |
Tokumasu, Kazuki
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
publons
researchmap
Ochi, Kanako
Center for Education in Medicine and Health Sciences, Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Otsuka, Fumio
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
publons
researchmap
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抄録 | A 42-year-old man who had suffered from severe fatigue for 5 years was diagnosed as having chronic fatigue syndrome (CFS) and fibromyalgia. Endocrinological workup using combined anterior pituitary function tests showed that the patient had adrenocorticotropin hormone (ACTH) deficiency, with a normal pituitary MRI. Treatment with a physiologic dose of oral hydrocortisone replacement physically ameliorated his general fatigue. A secondary workup using a growth hormone-releasing peptide-2 test revealed that he also had growth hormone (GH) deficiency, and GH replacement therapy was started. His muscle pain and depression were improved by the therapy. Here, we present a rare case of combined deficiency of ACTH and GH in a middle-aged man with severe general fatigue. This case report aims to raise awareness of combined deficiency of ACTH and GH as a differential diagnosis of CFS and its mimics.
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備考 | This article has been accepted for publication in BMJ Case Reports, 2021 following peer review, and the Version of Record can be accessed online at https://doi.org/10.1136/bcr-2021-244861
This is an Accepted Manuscript of an article published by BMJ
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発行日 | 2021-10
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出版物タイトル |
BMJ Case Reports
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巻 | 14巻
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号 | 10号
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出版者 | BMJ
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開始ページ | e244861
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ISSN | 1757-790X
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NCID | AA12533286
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | © BMJ Publishing Group Ltd ( for assignments of BMJ Case Reports)
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論文のバージョン | author
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PubMed ID | |
DOI | |
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関連URL | isVersionOf https://doi.org/10.1136/bcr-2021-244861
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Citation | Tokumasu K, Ochi K, Otsuka FIdiopathic combined adrenocorticotropin and growth hormone deficiency mimicking chronic fatigue syndromeBMJ Case Reports CP 2021;14:e244861.
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