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ID 63090
フルテキストURL
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著者
Tamura, Kazuya Department of Pathophysiology‑Periodontal Science, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Tokuzen-Tai, Masako Department of Periodontics and Endodontics, Okayama University Hospital
Siddiqui, Yasir Dilshad Department of Pathophysiology‑Periodontal Science, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Tamura-Naito, Hitomi Department of Periodontics and Endodontics, Okayama University Hospital
Nagahara, Yoshiharu Nagahara Animal Hospital
Hatanaka-Takeuchi, Kazu Department of Periodontics and Endodontics, Okayama University Hospital
Yamamoto, Tadashi Department of Pathophysiology‑Periodontal Science, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID publons researchmap
Takashiba, Shogo Department of Pathophysiology‑Periodontal Science, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences ORCID Kaken ID publons researchmap
抄録
Background
Periodontal disease is the most common dental disease in dogs. Although the systemic effects of periodontal disease have not been clarified in veterinary science, it is necessary to evaluate the effects of periodontal disease in clinical trials in the future. There have been a few clinical attempts made, however, to assess the severity of periodontal inflammation and its impact on the systemic health of dogs. Meanwhile, in the field of dentistry for humans, the periodontal inflamed surface area (PISA) and periodontal epithelial surface area (PESA) have been used to quantitatively assess the degree of periodontal disease affecting a single tooth as well as the overall extent of periodontitis. Recent studies have also suggested the use of these assessments to examine the relationship between periodontal inflammation and systemic health.

Results
The estimation formula for a dog's periodontal pocket surface area (PPSA), an alternative to PISA and PESA in humans, was established using body weight and periodontal pocket depth. Actual values were measured using extracted teeth from various dog breeds and sizes (2.3-25.0 kg of body weight) to obtain universal regression equations for PPSA. Altogether, 625 teeth from 73 dogs of 16 breeds were extracted and subsequently analyzed for morphological information. PPSA was measured in 61 dogs of 10 breeds with periodontal disease using the established estimation formulas, and the correlation between PPSA and preoperative blood chemistry data was analyzed accordingly. A strong correlation was found between PPSA and serum globulin (r = 0.71) while moderate correlations were found for C-reactive protein (r = 0.54) and serum albumin (r = -0.51).

Conclusions
Estimation formulas using body weight and the 6-point probing depth were established for determining PPSA. Direct correlations between PPSA and several blood test results were observed in the study sample. Taken together, these results suggest that PPSA could be useful for evaluating the effects of periodontitis on systemic conditions in dogs.
キーワード
Dog
Periodontitis
Periodontal pocket surface area
Estimation method
Periodontology
発行日
2022-01-03
出版物タイトル
BMC Veterinary Research
18巻
1号
出版者
BMC
開始ページ
13
ISSN
1746-6148
資料タイプ
学術雑誌論文
言語
英語
OAI-PMH Set
岡山大学
著作権者
© The Author(s) 2021.
論文のバージョン
publisher
PubMed ID
DOI
Web of Science KeyUT
関連URL
isVersionOf https://doi.org/10.1186/s12917-021-03116-0
ライセンス
http://creativecommons.org/licenses/by/4.0/.
Citation
Tamura, K., Tokuzen-Tai, M., Siddiqui, Y.D. et al. Estimation of periodontal pocket surface area in small to medium dogs: a proof-of-concept study. BMC Vet Res 18, 13 (2022). https://doi.org/10.1186/s12917-021-03116-0